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Occupational manganese exposure, reproductive hormones, and semen quality in male workers: A cross-sectional study.

It has been found that exposure to manganese (Mn) could induce reproductive dysfunction, but its occupational risk in male workers is unclear. This study aims to assess the association of occupational Mn exposure with reproductive hormones and semen quality in a cross-sectional study. Urinary Mn, semen quality, and reproductive hormones were explored in 84 male workers occupationally exposed to Mn and 92 referents. Multiple linear regression analyses were used to assess the relationship. Urinary Mn levels in Mn-exposed workers ranged from 0.56 to 34.25 µg/L, and the average level was 15.92 ± 8

Eosinophilic meningitis epidemiological data from a national database in Thailand's Department of Disease Control: a pragmatic, retrospective analytical study.

BACKGROUND: Eosinophilic meningitis (EOM) is a rare neurological disease that can be misdiagnosed or underdiagnosed. Based on reported cases in the literature, there have been 2,827 cases worldwide since 1945. There are limited data on the prevalence and trends of EOM in a real-world setting, even in Thailand, the country with the highest prevalence of EOM. Therefore, this study aimed to evaluate the prevalence of EOM and EOM epidemiological data in a real-world setting. METHODS: This was a pragmatic, retrospective analytical study using a national database. We retrieved EOM epidemiological d

Position Paper on Asbestos of the Italian Society of Occupational Medicine.

The Position Paper (PP) on asbestos of the Italian Society of Occupational Medicine (SIML) aims at providing a tool to the occupational physician to address current diagnostic criteria and results of epidemiological studies, and their consequences in terms of preventive and evaluation actions for insurance, compensation and litigation. The PP was based on an extensive review of the scientific literature and was compiled by a Working Group comprising researchers who have contributed to the international literature on asbestos-related diseases, as well as occupational physicians with extensive e

Seroprevalence of Q fever among high-risk occupations in the Ilam province, the west of Iran.

BACKGROUND: Q fever is a zoonotic disease of great public health importance in Iran. This disease is presented with high phase I antibody development in chronic and high phase II antibody in the acute form of illness. This study was conducted to evaluate the seroprevalence of Q fever among high-risk occupations in the Ilam province in Western Iran. METHODS AND FINDINGS: In this cross-sectional study, 367 sera samples were collected from five groups comprised of animal husbandry workers, farmers, butchers, slaughterhouse workers, and park rangers. The collected sera were tested for IgG antibod

Cumulative trauma disorders in betel pepper leaf-cullers visiting a rehabilitation clinic: experience in Taitung.

BACKGROUND: Betel pepper (Piper betle L.) cultivation is an important agricultural industry in Taitung, Taiwan, and culling leaves is very labor-intensive. This case study compares the proportion of cumulative trauma disorders (CTDs) between cullers and those with other occupations. METHODS: Patients with musculoskeletal disorders in the rehabilitation clinic of a local hospital in Taitung were enrolled. This all female cohort was divided into a culler group (betel pepper cullers, n = 20), and a non-culler group (other occupations, n = 47). Three cullers were interviewed, and were also record

Fathers' occupational contacts and risk of childhood leukemia and non-hodgkin lymphoma.

BACKGROUND: There is evidence to suggest that childhood leukemia and non-Hodgkin lymphoma have an infective etiology. We investigated the risk of childhood leukemia and non-Hodgkin lymphoma in relation to paternal occupational contact with other individuals, a surrogate for potential exposure to infection. METHODS: We carried out a case-control study using 792 cases from the Northern Region Young Persons' Malignant Disease Registry, United Kingdom, 1968-1997, and 2 large population-based control groups. Paternal occupations at birth were classified as having standard, high, or very high level

Hand workload and the metacarpal cortical index. a study of middle-aged teachers and dentists.

We studied load-related predictors (handedness, occupation and workload history) of cortical bone mass as estimated by the metacarpal cortic … ach other, when we controlled for potential confounders. The MCI decreased similarly by age in both occupational groups. Among the dentists, workload history was inversely associated with the MCI in multivariate analyses by age group. Computer use was a positive predictor for MCI among dentists aged 55-63 years. Occupational factors seem to have contradictory effects …

Sigma-1 and dopamine D2/D3 receptor occupancy of pridopidine in healthy volunteers and patients with Huntington disease: a [18F] fluspidine and [18F] fallypride PET study.

PURPOSE: Pridopidine is an investigational drug for Huntington disease (HD). Pridopidine was originally thought to act as a dopamine stabilizer. However, pridopidine shows highest affinity to the sigma-1 receptor (S1R) and enhances neuroprotection via the S1R in preclinical studies. Using [18F] fluspidine and [18F] fallypride PET, the purpose of this study was to assess in vivo target engagement/receptor occupancy of pridopidine to the S1R and dopamine D2/D3 receptor (D2/D3R) at clinical relevant doses in healthy volunteers (HVs) and as proof-of-concept in a small number of patients with HD.

The effect of energy conservation strategies on fatigue, function, and quality of life in adults with motor neuron disease: Randomized controlled trial.

Background: Fatigue is one of the most frequent complaints in patients with motor neuron diseases (MNDs), with a significant impact on the quality of life (QOL). There is lack of enough evidence for current pharmacological or non-pharmacological treatments of fatigue in this population to be applied in clinical setting. Energy conservation strategies are one of the key interventions for fatigue management in chronic diseases. We aimed to investigate the effect of applying these techniques in the fatigue management of patients with MND. Methods: This randomized controlled trial (RCT) study was

[BK 2118: knee osteoarthritis in professional football : Expert assessment of occupational exposure, sports injury, and competing causes].

BACKGROUND: German occupational disease no. 2118 covers knee osteoarthritis in female and male professional football players after at least 13 years of exposure. The disease phenotype corresponds to that of occupational disease no. 2112; exposure and individual causation are distinct. OBJECTIVES: To develop a practical pathway separating cumulative professional football exposure from the consequences of specific ligament, meniscal, or cartilage injuries and other competing causes. MATERIALS AND METHODS: The statutory definition, scientific recommendation, explanatory materials, guidance for

Coal Workers' Pneumoconiosis-Associated Deaths - United States, 2020-2023.

Coal workers' pneumoconiosis (CWP) is a preventable, progressive occupational lung disease caused by inhaling respirable coal mine dust, a complex mixture commonly containing coal, crystalline silica, and other silicate minerals. Early pneumoconiosis can be asymptomatic, but advanced disease often leads to disability and premature death. To describe CWP-associated mortality among U.S. residents aged ≥15 years by industry and occupation, CDC conducted an exploratory analysis of National Vital Statistics System multiple cause-of-death data for 2020-2023, the most recent years that include inform

Факторы, связанные с саморегистрацией способностей к труду у людей с множественным склерозом в Швеции.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Индекс способностей к труду (ИПТ) является инструментом, измеряющим способность к труду при проведении обследований на рабочем месте и медицинских обследований в области гигиены труда и исследований. Он используется в различных группах населения. Но исследования ограничены среди людей с множественным склерозом (PwMS). ЦЕЛЬ: Определение факторов, связанных с производственными способностями, среди ПТМС в Швеции. МЕТОДЫ: В анализ было включено в общей сложности 4103 ПВМС, которые ответили на вопросы обследования на базе Интернета. Способность к труду оценивалась с использов

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… Work ability score by occupation Across occupational groups, WAS showed that, on average, managers reported (mean = 7.9, standard deviation (SD) = 1.9) statistically significantly higher score than workers with office jobs (mean = 7.4, SD = 2.3), manual jobs (mean = 7.1, SD = 1.9), and those with no …

Listening to Video Game Voices: A Call for Action for Research into the Vocal Health of Video Game Voice Actors.

Video game voice actors (VGVAs) are a professional voice user (PVU) population whose occupation relies on their ability to reliably deliver extremes in vocal performance. In their work VGVAs are required to perform solo for extended durations, producing highly complex character performances that not only include extremes of vocal parameters and qualities but also highly demanding vocal acts (ie, screaming, singing) within those voice archetypes. Based on the vocal demands of their work and current understandings of occupational voice disorder, it is reasonable to consider that VGVAs may be at

Assessment of air pollution and its effects on the health status of the workers in beam rolling mills factory (Iran National Steel Industrial Group) from Ahvaz-Iran.

BACKGROUND: Air pollutants of iron- and steel-making operations have historically been an environmental and health hazard. These pollutants include gaseous substances such as sulfur oxide, nitrogen dioxide, and carbon monoxide. The Iran National Steel Industrial Group beam rolling mills factory has two production lines viz. line 630 and line 650, with different beam production capabilities and is capable of producing different types of beams. MATERIALS AND METHODS: A retrospective cross-sectional study on 400 workers in different exposure levels to environmental pollution was performed during

Cork workers' occupational asthma: lack of association with allergic sensitisation to fungi of the work environment.

OBJECTIVES: To evaluate allergic sensitisation to Chrysonilia sitophila, Penicillium glabrum, and Trichoderma longibrachiatum in cork workers with asthma. METHODS: Skin prick tests with a battery of common allergens and with the three fungi were performed on ten cork workers with asthma and eight non-exposed asthmatics. Based on serial peak expiratory flow measurements, five were classified as having occupational asthma (AO) and five as having non-occupational asthma (NOA). In exposed patients, specific antibodies for the three fungi were also studied by immunoblotting RESULTS: Two out of te

[An analysis of industrial accidents in the working field with a particular emphasis on repeated accidents].

The present study is based on an analysis of routinely submitted reports of occupational accidents experienced by the workers of industrial enterprises under the jurisdiction of Kagoshima Labor Standard Office during a 5-year period 1983 to 1987. Officially notified injuries serious enough to keep employees away from their job for work at least 4 days were utilized in this study. Data was classified so as to give an observed frequency distribution for workers having any specified number of accidents. Also, the accident rate which is an indicator of the risk of accident was compared among diffe

Evaluation of lung cancer early detection offered by the German Social Accident Insurance for formerly asbestos-exposed employees using low-dose computed tomography - setting and study design.

BACKGROUND: Clinical trials have shown the benefits of lung cancer screening (LCS) in certain high-risk groups using low-dose high-resolution computed tomography (LDCT). Risk groups are usually defined by age and tobacco use. Exposure to asbestos dust is an important occupational risk factor for lung cancer. Since 2014, the German Social Accident Insurance (DGUV) has introduced annual LCS for high-risk groups (EVA-LCS). In addition to occupational asbestos dust exposure, the population at risk is defined by age (≥ 55 years) and tobacco consumption (≥ 30 pack-years). The health services researc

[A case-control study of occupational noise exposure induced high-frequency hearing loss and the risk of hypertension].

Objective: To investigate the relationship between high frequency hearing loss caused by occupational noise and the risk of hypertension. Methods: In March 2020, a case-control study was conducted. All noise exposed workers who participated in occupational health examination in Wuxi City in 2019 were selected as the study subjects (95432 cases in total) . The hypertension group was defined as the case group, and the normotensive group was defined as the control group. According to the hearing threshold, they were divided into the non high frequency hearing loss group (<40 dB) and the high freq

[Expression and functional SNP loci screen of ATM from coal worker's pneumoconiosis].

Objective: To detect of gene expression and genotype of the ataxia telangiectasia mutated (ATM) from coal workers' pneumoconiosis (CWP) , It is explored whether CWP is related to ATM gene. Methods: In October 2020, the relevant information of 264 subjects who received physical examination or medical treatment in the Department of occupational diseases of Guiyang public health treatment center from January 2019 to September 2020 was collected. Through the occupational health examination, 67 healthy people with no history of exposure to occupational hazards were selected as the healthy control g

Infrared radiation and cataract.

The study was undertaken to determine if occupational exposure to infrared (IR) radiation increases the risk of developing cataract. The study includes epidemiologic investigations of two groups of workers exposed to IR radiation and two groups of non IR-exposed controls. The first investigation included 208 iron and steel workers and 208 controls. For each of the workers, the lifetime IR-exposure was calculated with the help of occupational interviews and measurements of the IR-exposure to their eyes in their jobs. Eye examinations including a detailed slit lamp examination of the lens were m