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Surgical procedures in glaucoma: A preferred practice pattern report by the Latin American Glaucoma Society.

PURPOSE: To evaluate the preferred surgical practice patterns for glaucoma among members of the Latin American Glaucoma Society. METHODS: A … had more than 20 yr of professional experience. For the surgical management of open-angle glaucoma, trabeculectomy was the most preferred procedure (48 physicians), followed closely by glaucoma drainage devices (47 physicians) and minimally invasive glaucoma surgery (29 physicians). Across the 10 clinical scenarios, glaucoma drainage devices were selected most f …

Effectiveness of glaucoma surgery in preserving corneal transparency in patients with primary open-angle glaucoma.

AIM: Our study's aim was to examine possible changes in Scheimpflug corneal densitometry among patients with primary open-angle glaucoma (POAG) 12 months after trabeculectomy compared with healthy controls. METHODS: A total of 35 eyes from 35 patients diagnosed with POAG and 34 eyes from 34 age-matched healthy controls were included. Corneal densitometry with Scheimpflug Pentacam HR corneal topography was evaluated in three corneal regions (i.e., 0-2, 2-6, and 6-10 mm) and four quadrants (i.e., upper, lower, temporal, and nasal) in patients before and 12 months after trabeculectomy and compar…

Surgical Management of Primary Congenital Glaucoma: Results of a Nationwide Descriptive Study in France (CONGLAU).

PURPOSE: Childhood glaucoma is rare but severe, with no recognized standard surgical procedure. We conducted a retrospective, observational, … were included. The most common surgeries were trabeculotomy (31.0%) and trabeculotomy combined with trabeculectomy (20.7%). A further 11 other types of surgery were performed for <10% of eyes. Median IOP was reduced in each surgical group at 1 month (the largest median reduction being for combined trabeculotomy/non-perforating deep sclerectomy [-60%]) and at 1-y …

Real-world Surgical Outcomes of Primary Angle-closure Glaucoma.

PURPOSE: To evaluate surgical outcomes of the four common procedures utilized for primary angle-closure glaucoma (PACG). METHODS: A retrospective study of survival rate in surgical management of PACG was conducted in a referral eye center. One hundred and ninety-nine eyes from 173 PACG patients were collected for chart review. The procedures used were phacoemulsification (PE), combined PE with goniosynechialysis (PE-GSL), combined PE with trabeculectomy (PE-Trab), and trabeculectomy alone. Failure was defined as postoperative IOP >21 mmHg in patients who needed second surgical intervention or…

The role of LOX and LOXL2 in scar formation after glaucoma surgery.

PURPOSE: The aim of this study was to elucidate the role of lysyl oxidase (LOX) and lysyl oxidase like (LOXL) 2 in pathologic wound healing after glaucoma surgery. We therefore investigated the expression of LOX and LOXL2 and evaluated the therapeutic potential of anti-LOX (GS-639556, formerly M64) and anti-LOXL2 (GS-607601, formerly AB0023) antibodies in a rabbit model of glaucoma trabeculectomy. METHODS: Ocular expression of LOX and LOXL2 was investigated by immunohistologic staining at different time points after trabeculectomy. Treatment with GS-639556 or GS-607601 was initiated in rabbit…

Effect of beta radiation on success of glaucoma drainage surgery in South Africa: randomised controlled trial.

OBJECTIVE: To evaluate whether beta radiation may offer a practical method of improving surgical success for glaucoma drainage surgery in South Africa. DESIGN: Double blind, randomised controlled trial. SETTING: Three public hospitals in South Africa. PARTICIPANTS: 450 black Africans with primary glaucoma. INTERVENTIONS: Trabeculectomy with 1000 cGy beta radiation or standard trabeculectomy without beta radiation (placebo). MAIN OUTCOME MEASURES: Primary outcome measure was surgical failure within 12 months (intraocular pressure > 21 mm Hg while receiving no treatment for ocular hypotensi…

Risk Factors for Severe Bleeding Complications in Glaucoma Surgery and the Role of Antiplatelet or Anticoagulant Agents.

PURPOSE: To evaluate the influences and risk factors for severe bleeding complications during glaucoma surgery, and to investigate the role of antiplatelet (AP) and anticoagulant (AC) agents. METHODS: This prospective study enrolled patients undergoing trabeculectomy, trabeculotomy (with Trabectome® or Kahook Dual Blade®), viscocanaloplasty and Ahmed or Baerveldt implants. Bleeding severity was graded on an ordinal scale ranging from 0 to 5. Immediately after surgery and one day later, the incidence and severity of bleeding events was documented on a standardized form. A grade ≥3 was defined …

Scleral free auto-implant plug with mitomycin as limitation of trepanosclerectomy flow in glaucoma filtering surgery.

UNLABELLED: The purpose of this study is to evaluate the effect of trephination with free scleral auto-implant plug exposed to Mitomycin-C out of the eye, in surgical treatment of primary open-angle glaucoma (POAG), in comparison with efficacy of trabeculectomy with MMC (32 eyes with POAG of patients, younger than 55 years-group 1). Trephination with scleral auto-implant plug with MMC was done on 35 eyes of patients, younger than 55 years, with POAG (group 2). The postoperative follow-up was 28.52 +/- 8.78 months. SURGICAL PROCEDURE: A limbal 1.0 mm diameter trephination is made beneath the l…

Связанный с кровью эндофтальмит во время эпидемии вирусного кератоконъюнктивита.

Годовая эпидемия вирусного конъюнктивита происходит в начале сезона муссонов в Северной Индии. Это сказывается на большом населении, при этом у многих пациентов возникают окулярные симптомы, а затем они становятся лучше без какого-либо лечения, поскольку не существует специальной терапии для аденовальных инфекций. Однако это создает опасную ситуацию для пациентов с операционной трабекулектомией с фильтрующим кровотечением, поскольку конъюнктивит может привести к блебиту и блебному эндофтальмиту с супердостаточными бактериальными/фенгальными инфекциями. В то время как вирусная инфекция является

Совпадение в аннотации оригинала
There is an annual epidemic of viral conjunctivitis at the onset of the monsoon (rainy) season in North India. This affects a large populati … y for adenoviral infections. However, this creates a dangerous situation for patients with operated trabeculectomy with a filtering bleb as conjunctivitis can lead to blebitis and bleb-related endophthalmitis with super-added bacterial/fungal infections. While the viral infection is self-limiting and most patients get well without treatment, urgent medical atten …

LARGE RETINAL PIGMENT EPITHELIAL RIP ASSOCIATED WITH BULLOUS RETINAL AND CHOROIDAL DETACHMENT.

PURPOSE: To report a giant retinal pigment epithelium rip in a patient with a bullous retinal and choroidal detachment. METHODS: Case report with widefield imaging, fundus autofluorescence, and optical coherence tomography of the retina. RESULTS: This 62-year-old patient had a history of advanced glaucoma, trabeculectomy, blebitis, and endophthalmitis. He had cataract surgery 6 weeks before presentation. He was found to have a large bullous retinal and choroidal detachment with a large retinal pigment epithelium tear at the limit of the choroidal detachment. After vitrectomy for retinal deta…

LARGE RETINAL PIGMENT EPITHELIAL RIP ASSOCIATED WITH BULLOUS RETINAL AND CHOROIDAL DETACHMENT.

PURPOSE: To report a giant retinal pigment epithelium rip in a patient with a bullous retinal and choroidal detachment. METHODS: Case report with widefield imaging, fundus autofluorescence, and optical coherence tomography of the retina. RESULTS: This 62-year-old patient had a history of advanced glaucoma, trabeculectomy, blebitis, and endophthalmitis. He had cataract surgery 6 weeks before presentation. He was found to have a large bullous retinal and choroidal detachment with a large retinal pigment epithelium tear at the limit of the choroidal detachment. After vitrectomy for retinal deta…

Use of indocyanine green during excision of an overhanging filtering bleb.

BACKGROUND: We report the use of an indocyanine green (ICG) injection during the safe removal of an overhanging filtering bleb after trabeculectomy. CASE: A 63-year-old man with a history of trabeculectomy 5 years previously in his left eye complained of foreign body sensation in this eye and decreased vision from induced astigmatism. Slit-lamp examination revealed an expanding overhanging filtering bleb on the cornea. OBSERVATIONS: With a 30-G needle, 0.25% ICG was injected into the overhanging bleb. Use of ICG visualization of the inner space of the overhanging filtering bleb provided visu…

Results of filtering surgery in young patients with aniridia.

To evaluate whether filtering surgery is effective in controlling the intraocular pressure of young aniridic patients with glaucoma, we retrospectively reviewed the charts of aniridic patients with glaucoma under the age of 40 years. We defined a good intraocular pressure control period as the time from surgery until IOP exceeded 20 mm Hg, with or without glaucoma medication. Twenty filtering surgeries (17 trabeculectomies and 3 trabeculectomies with mitomycin C) were performed on 10 eyes in 6 patients for more than 20 years. The mean good intraocular pressure control period after the filterin

Intraoperative prediction of intraocular pressure for the first postoperative day following glaucoma filtration surgery.

The goal of glaucoma filtering surgery is to achieve adequate control of intraocular pressure (IOP). This prospective study evaluates the authors' accuracy in predicting IOP for the first postoperative day (POD 1) through digital palpation of the globe and evaluation of the achieved leakage at the end of trabeculectomy. Fifty patients underwent trabeculectomy with or without the use of an antimetabolite. At the conclusion of the procedure, an IOP prediction for POD 1 was given by the surgeon. The recorded IOP readings on POD 1 were compared with this prediction. The results were evaluated by l…

Our Experience of Deep Sclerectomy at a Tertiary Center in the United Kingdom Over 14 Years.

Background Deep sclerectomy (DS) is a non-penetrating surgical procedure for glaucoma, reducing the resistance to aqueous outflow and loweri … 5%), goniosynechiolysis (1.25%), and autologous blood injection (1.25%). Two eyes were converted to trabeculectomy peri-operatively, with seven overall (8.75%) requiring trabeculectomy over the course of follow-up. 3.75% underwent glaucoma drainage device implantation, and 3.75% underwent cyclodiode laser. Conclusion We have found DS to be a safe, effective proc …

Management of postoperative inflammation after cataract and complex ocular surgeries: a systematic review and Delphi survey.

Prevention and management of postoperative ocular inflammation with corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs) have … gery; ketorolac was effective (1/1) after vitrectomy, but triamcinolone was ineffective (0/1) after trabeculectomy. A two-round Delphi survey asked 28 international experts to rate both the inflammatory potential of different eye surgeries and their agreement with different treatment protocols. They rated trabeculectomy, RD surgery and combined phacovitrectomy a …

Safety and efficacy of collagen matrix implantation in infantile glaucoma.

PURPOSE: To evaluate the preliminary results of biodegradable collagen matrix implant (Ologen) designed to improve outcome in patients with infantile glaucoma undergoing combined trabeculotomy and trabeculectomy. METHODS: A biodegradable collagen matrix (OculusGen) was placed in the subconjunctival space, partially over the scleral flap and the sclera in 20 eyes of 11 patients with infantile glaucoma who underwent combined trabeculotomy and trabeculectomy. Patients were examined preoperatively and on the first postoperative day with multiple postoperative follow-up visits within 12 months aft…

Impact of trastuzumab on wound healing in experimental glaucoma surgery.

BACKGROUND: To investigate the effects of subconjunctivally administered trastuzumab on wound healing in experimental glaucoma filtration surgery. DESIGN: Comparative, experimental study. SAMPLES: Twenty eight eyes. METHODS: Twenty-eight male New Zealand white rabbits were randomly assigned to four groups, each including seven rabbits: The rabbits in the control group were not operated on and did not receive any treatment. The rabbits in the sham group underwent trabeculectomy and had one drop of saline instilled four times a day for 14 days. The rabbits in the mitomycin-C group underwent t…

Mitomycin-C needle bleb revision in congenital glaucoma.

UNLABELLED: PURPOSE AND SETTINGS: This study was designed to evaluate the efficacy and safety of mitomycin-C (MMC) augmented needling procedure in the management of failed bleb after trabeculectomy in congenital glaucoma. This study was carried out at Ain Shams University Hospital. PATIENTS AND METHODS: A retrospective study was carried on 30 eyes of 25 patients with congenital glaucoma with bleb failure after trabeculectomy. The mean age of the subjects was 7.3 ± 3.4 years (range, 1-12 years). Under general anesthesia, needling procedure was performed with adjunctive use of a mixture of 0.1 …

Effects of postoperative cyclosporine ophthalmic emulsion 0.05% (Restasis) following glaucoma surgery.

PURPOSE: To determine if postoperative topical cyclosporine 0.05% has any beneficial effect following trabeculectomy. METHODS: This was an interventional, randomized, prospective, double-masked clinical trial of 44 consecutive patients with uncontrolled glaucoma requiring filtration surgery. Ocular surface disease index questionnaire and comprehensive ocular exam, including Schirmer's tear test 1, were performed. Patients underwent routine trabeculectomy, with or without phacoemulsification. The study group (n = 22) received cyclosporine 0.05%, and the control group (n = 22) received artifici…