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[Antibiotic prophylaxis in multiple trauma patients].

Infection prophylaxis in multiple trauma patients includes prophylaxis of infections due to surgery, which is the true one as well as the pr … atment of haemorrhagic shock. Other preventive measures, such as early enteral nutrition, selective decontamination of the digestive tract and immunotherapy, still need to prove their efficacy.

Acute Iron Poisoning: A Case of Fulminant Hepatic Failure.

Acute iron poisoning is an exceedingly rare occurrence, mainly when resulting from intentional ingestion in adults. It can lead to multi-organ toxicity and, in severe cases, may evolve into acute liver failure and cardiovascular collapse, which are the main causes of death. The clinical outcome is largely dependent on the amount of elemental iron ingested and the readiness of treatment, which includes support, early intestinal decontamination and deferoxamine. Despite timely intervention, acute liver failure can be life-threatening, with liver transplantation being the only potentially life-sa…

[THE USE OF PROBIOTICS IN PATIENTS WITH RHEUMATOID ARTHRITIS].

The results of biological research of colon microbiota of patients with rheumatoid arthritis (RA) is in article presented. The signs of III … terium spp., Bacteroides spp., Lactobacillus spp., typical E. coli, Enterococcus spp. and selective decontamination of Enterococcus (Hly+), Klebsiella spp., Proteus spp., Staphylococcus spp., lactosonegative and E.coli (Hly+) confirmed after using of this eubiotics.

[Acinetobacter].

Acinetobacter spp. are increasingly important nosocomial pathogens and are capable of rapid adaptation to the hospital environment. National … ates has been identified in Japan and other countries. Hand-washing policy and practices with daily decontamination of medical-devices or hand-contact environment should control nosocomial infection by Acinetobacter.

Болезнь сумасшедшей коровы - связь с операционной.

Болезнь Креуцфельдта-Якоба (CJD) — одна из трансмиссивных губчатых энцефалопатий, группа смертельных нейродегенеративных расстройств, затрагивающих как людей, так и животных. Побудительный агент - это прион, который все еще изучается и является спорным. В 1980-х годах говядина, говядина, привлекла много внимания средств массовой информации к этим заболеваниям. Энцефалопатия говяжьей губки является результатом неправильной промышленной практики, производящей корм скотоводов, загрязненных прионами. В 1990-х годах в Великобритании появился новый вариант CJD (т.е. nvCJD). Исследователи считают, чт

Совпадение в аннотации оригинала
Creutzfeldt-Jakob disease (CJD) is one of the transmissible spongiform encephalopathies, a group of fatal, neurodegenerative disorders affec … ory, causative agent, mode of transmission, clinical features and course, diagnosis, treatment, and decontamination and sterilization guidelines for this baffling disease.

Acute intravaginal misoprostol toxicity with fetal demise.

We report a case of an overdose with fetal demise from the intravaginal administration of misoprostol. A 25-yr-old gravid female self-admini … ered by emergent cesarean section. Treatment of the mother was supportive and included intravaginal decontamination and endotracheal intubation with neuroparalytic therapy to control agitation and hyperthermia. Recovery was complete within 15 h of drug administration.

Clinical demonstration of isolation of Nocardia asteroides on buffered charcoal-yeast extract media.

Nocardia asteroides was isolated only from sputum samples, obtained from three patients with pulmonary nocardiosis, that had been cultured onto buffered charcoal-yeast extract (BCYE) and selective BCYE media as part of laboratory workups for Legionella species. A decontamination procedure with low-pH pretreatment (KCl-HCl solution) had been performed on the sputa prior to culture onto the BCYE media because direct cultures on the media were overgrown with commensal microflora. Chalky white colonies, 0.5 to 1.0 mm in diameter, that were subsequently identified as N. asteroides grew well on the …

Acute Cade Oil Poisoning in Children: Report of Two Cases.

Cade oil, widely used in traditional Moroccan medicine for its perceived therapeutic properties, can lead to severe toxicity when ingested or applied extensively to the skin, particularly in infants and young children. We report two cases of toddlers who developed altered consciousness following widespread topical application. Laboratory findings revealed mild hepatic cytolysis and inflammatory markers, though imaging and cerebrospinal fluid analysis were normal. Both patients responded well to supportive care, including thorough decontamination and close clinical monitoring, and made a full r…

Carbapenems in the management of valproic acid overdose.

Severe valproic acid (VPA) overdose is characterized by coma (sometimes with cerebral oedema), respiratory depression, hypotension and metabolic abnormalities. Traditional management of VPA poisoning has been limited to gastrointestinal decontamination, L-carnitine supplementation and, in severe cases, haemodialysis. Recently, interest has developed in the use of carbapenem antibiotics as an adjunctive therapy in patients with severe VPA poisoning. Carbapenems inhibit acylpeptide hydrolase, the enzyme responsible for reconstituting VPA from VPA-glucuronide, and transiently promote distribution…

Advances in the treatment of portal hypertension in cirrhosis.

Non-selective beta-blockers and handling of esophageal varices has been key elements in the treatment of portal hypertension in recent decad … s of portal hypertension has revealed promising areas of treatment modalities, targeting intestinal decontamination, angiogenesis, inflammation and oxidative stress. Future studies may reveal if these initiatives lead to developments of new drugs for treatment of portal hypertension.

Evaluation of new antibiotic cocktails against contaminating bacteria found in allograft tissues.

Contamination of retrieved tissues is a major problem for allograft safety. Consequently, tissue banks have implemented decontamination protocols to eliminate microorganisms from tissues. Despite the widespread adoption of these protocols, few comprehensive studies validating such methods have been published. In this manuscript we compare the bactericidal activity of different antibiotic cocktails at different temperatures against a panel of bacterial species frequently isolated in allograft tissues collected at the Treviso Tissue Bank Foundation, a reference organization of the Veneto Region …

Creutzfeldt-Jakob disease: recommendations for disinfection and sterilization.

Prion diseases constitute a unique infection control problem because prions exhibit unusual resistance to conventional chemical and physical decontamination methods. Recommendations to prevent cross-transmission of infection from medical devices contaminated by Creutzfeldt-Jakob disease (CJD) have been based primarily on prion inactivation studies. The recommendations in this article consider inactivation data but also use epidemiological studies of prion transmission, infectivity of human tissues, and efficacy of removing microbes by cleaning. On the basis of the scientific data, only critica…

Investigation and control of a cluster of cases of Legionnaires disease in western Sydney.

Three cases of Legionella pneumophila infection were identified in Sydney's west in November 1998. Epidemiological investigations identified … entially linked to disease with counts of LP1 below the current protocol requirements for immediate decontamination.

Pseudomonas aeruginosa orbital phlegmon in a patient treated for myelodysplastic syndrome with concomitant Sjögren's syndrome.

Pseudomonas aeruginosa orbital infections have been described very rarely in patients with neutropenia after chemotherapy. We report the case of a woman with the unusual association of Sjögren's disease and myelodysplasia, who suffered from a Pseudomonas aeruginosa orbital phlegmon after chemotherapy for her myelodysplastic syndrome. Partial intestinal antibiotic decontamination with ciprofloxacine did not prevent the infection. She was treated successfully with intravenous ceftazidime, netilmicin and granulocyte-colony stimulating factor (G-CSF). The normalization of the granulocyte count see…

Rapid Determination of Cocaine and Its Metabolite Benzoylecgonine in Hair by LC-MS/MS.

OBJECTIVES: To establish a rapid determination method with LC-MS/MS for cocaine and its metabolite benzoylecgonine in hair. METHODS: Deuterated internal standards （cocaine-D₃ and benzoylecgonine-D₈） were added to the decontaminated hair. After the extraction by ultrasonication with methanol, the compounds were separated by the Restek Allure PFP propyl column, and cocaine and benzoylecgonine were simultaneously analysed in multiple reaction monitoring mode. RESULTS: The cocaine and benzoylecgonine in hair showed a good linearity in the range of mass fraction between 0.02 and 10.00 ng/mg with

Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report.

Medication-related osteonecrosis of the jaws is a delayed healing condition commonly recognized as a serious adverse effect of antiresorptive therapy and is particularly associated with aminobisphosphonate treatment. In the present report, a 62-year-old osteoporotic female patient treated with intramuscular injections of clodronate for 3 years exhibited clinical signs of exposed necrotic bone and inflamed mucosa 4 months after tooth extractions in the mandibular interforaminal region. The treatment consisted of sequestrectomy, open-flap debridement, and adjunctive use of antimicrobial photodyn

Use of a diode laser in an excisional biopsy of two spoonlike neoformations on the tongue tip.

The 810 nm diode laser, due to its high affinity with haemoglobin (elective chromatophore) revealed, by itself, as elective instrument for surgical excision of the tongue, an organ highly vascularized and sensitive to the laser cutting action. The advantages for its use, with respect to the traditional cold blade surgery, are its haemostatic effect (which avoids to close wounds by stitches) and, not less important, the decontaminant effect of the laser ray, due to either the thermal raising created on cutting line and/or the specific selective action exerted on the bacterial membrane by its wa

Urinary catheter-related infection: an education programme for users.

While infection control has increased in profile both clinically and politically, it has also become embedded in clinical governance frameworks of NHS Trusts. Over the last few years the Department of Health has produced a number of documents in an attempt to highlight the increasing risk of healthcare associated infection. Today, the need for education as a key component in health care has been recognized as well as the need for patients and carers to receive information and be trained in, for example, technique of hand decontamination and catheter management following discharge from hospital…

The mechanics of endoscope disinfection.

The decontamination of flexible fibreoptic endoscopes has considerably improved in recent years. This is mainly due to the introduction of instruments with more accessible channels, the use of automated washer disinfectors and a greater awareness of the problems associated with disinfection. Unfortunately the most widely used and effective disinfectant is 2% glutaraldehyde and this is toxic, irritant and sensitizing. With the implementation of Control of Substances Hazardous to Health legislation, strict environmental controls are required to reduce skin contact and vapour inhalation. Alcohol …

Sanitation of medical cannabis flowers (Cannabis sativa L., flos): comparing current technologies and non-thermal plasma novelties from safety and quality perspectives.

The use of cannabis in medicine has rich historical roots spanning thousands of years before stigmatism surrounding the narcotic use of this … ist on the plant and the efficacy of sanitation methods currently used in the food industry for the decontamination of cannabis. Specifically, irradiation methods such as gamma irradiation and electron beams have been applied to effectively lower the microbial load on cannabis. However, these irradiation methods face pushbacks due to cost barriers, regulatory iss …