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Is a single calibration for the TloadDback cognitive fatigue induction task reliable?

TloadDback task was introduced as a novel task for inducing cognitive fatigue by accounting for the cognitive capacity of each individual's processing time needs stimulus time duration (STD). The task is carried out on different days with calibration occurring on 1 day and fatigue induction occurring on another. The aim of this within subjects study is to assess the reliabilityThe of a single calibration. Fifty-one healthy participants (age = 32.2 +/- 13.45; sex F = 41) completed the TloadDback calibration phase on three different days at three different moments of the day (counterbalanced for…

The Rheological and Fatigue Properties of Waste Acetate Fiber-Modified Bitumen.

The rheological properties of fiber-reinforced binders are remarkable. The research on acetate fibers as reinforcing agents is scant. Acetate fibers exhibit more environmental benefits than lignocellulose and other fibers. In this study, acetate fibers were pretreated with anhydrous ethanol as the extractant to disperse the fibers uniformly in the bitumen and the high/medium-temperature fatigue properties of waste acetate fibers blended with binders were investigated. Infrared spectroscopy (FT-IR) tests showed that pretreatment was effective in removing plasticizers from CBs so that the fibers…

Vocal Fatigue in Mandarin-Speaking Teachers: Characteristics of Phonation and Resonance.

OBJECTIVE: To investigate phonatory and resonatory characteristics in Mandarin-speaking female teachers with vocal fatigue (VF). METHODS: A case-control study was conducted among teachers in Shanghai, China. Participants included 18 vocal-fatigued teachers (VF), 17 non-vocal-fatigued teachers (NVF), and 16 nonoccupational voice users (NOVU). Subjective assessment included the Vocal Fatigue Index (VFI), Voice Handicap Index-10 (VHI-10), and GRBAS scale. Objective assessments included maximum phonation time (MPT), dysphonia severity index (DSI), fundamental frequency (F0), cepstral peak promine…

FES-Induced and Voluntary-Induced Fatigue in a Rehabilitation-Like Task.

In the context of FES-based rehabilitation and assistance tasks, there is a growing interest in managing the induced fatigue, which is an obvious limiting factor in training duration. However, it is unclear whether and how fatigue may develop in tasks commonly used in stroke rehabilitation. This work explored the effect of FES- or volition- induced movements on EMG-based effort and M-wave metrics that characterise fatigue, during a continuous wrist target-tracking task completed by 22 unimpaired participants. We found no significant changes in the mechanical and electrical responses of the mus…

The Dual Role of Myokines in Fatigue Associated with Inflammatory Joint Diseases.

Fatigue is a prevalent and debilitating symptom in rheumatic diseases such as rheumatoid arthritis and psoriatic arthritis. Despite advances in reducing inflammation through treatments, fatigue often persists, underscoring its multifactorial etiology. A possible link between the persistent inflammation observed in rheumatic diseases and the onset of fatigue has been suggested. The discovery that skeletal muscles also secrete cytokines and myokines, has opened new avenues for research. This narrative review explores current mechanistic insights and evidence on the dural role of myokines in exac…

Exploration of Intersections and Divergences of Long COVID and Chronic Fatigue Syndrome.

BACKGROUND: Fatigue is the most common symptom of Long COVID (LC), defined by persistent or newly emerging symptoms that develop at least three months after an initial SARS-CoV-2 infection, in the absence of other identifiable cause. This study investigates the prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) as a potential comorbidity of LC. METHODS: The study enrolled 37 adult controls with no documented SARS-CoV-2 infection and 32 individuals with a history of infection, categorized as LC-yes (with LC symptoms) and LC-no (without LC symptoms). ME/CFS diagnosis was …

The effects of hip abductor fatigue on gait instability in older adults.

Fatigue is a critical factor governing muscle force responsiveness and, thereby, capacity to respond to balance challenges. Mediolateral stability is crucial for older adults to safely navigate their daily environments and disproportionally requires active control; the hip abductors are the key muscles in regulating lateral foot placement and mediolateral stability. Our study aimed to characterize the effects of hip abductor fatigue on gait instability in a cohort of older adults. We hypothesized that fatigue, as induced by continuous lateral stepping, would compromise mediolateral walking bal…

Listen to Patient's Gut: A Case Report of a Woman With Fatigue and Bruising.

A 65-year-old female patient with dermatomyositis and lipodystrophy presented with fatigue and severe anemia. Abdominal auscultation revealed a loud hum in the epigastrium, consistent with a Cruveilhier-Baumgarten murmur, typically associated with portal hypertension. Magnetic resonance imaging showed signs of portal hypertension, including recanalization of paraumbilical vein. Liver biopsy demonstrated sinusoidal dilation without cirrhosis, leading to a diagnosis of portosinusoidal vascular disease. Upper endoscopy confirmed portal hypertensive gastropathy as the cause of anemia. This case hi…

Psychological Distress and Fatigue in Polycystic Ovarian Syndrome: A Pilot Study.

BACKGROUND: Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder affecting both physical and psychological health in women of reproductive age. While its metabolic and reproductive symptoms are well-documented, fatigue remains an underrecognised yet significant concern. Psychological distress, including anxiety, depression and stress, may contribute to fatigue in women with PCOS, either directly or by influencing sleep disturbances. While insomnia is commonly reported in this population, this study primarily focuses on fatigue and its association with psychological distress, with…

Factors Associated with Sleep Disruption and Fatigue in Thyroid Cancer Survivors.

Thyroid cancer survivors often experience worse quality of life than other cancer survivors, with fatigue and sleep disturbance being common contributors. In this prospective cohort from the ICaRe2 cancer registry, survivors completed the Brief Fatigue Inventory (BFI) and Pittsburgh Sleep Quality Index (PSQI) at enrollment and follow-up, with univariate and multivariable analyses identifying factors associated with fatigue and sleep quality. Among 249 survivors (83% female, median age 42), 205 completed the BFI and 224 the PSQI. Most were low (57%) or intermediate (34%) risk or recurrence at d…

Managing fatigue in Parkinson's disease: Preparing for a randomized controlled trial.

BackgroundFatigue in Parkinson's disease (PD) is a common, debilitating symptom often overlooked in research and clinical practice. Effective interventions are needed to mitigate its impact on people with PD.ObjectiveThis pilot study evaluated the feasibility of the individual videoconference version of the Packer Managing Fatigue program for people with PD and explored its preliminary effectiveness versus usual care to inform the design of a definitive trial. Here we report on the second objective.MethodsA two-arm, assessor-masked, randomized controlled pilot study recruited participants with…

Усталость при множественном склерозе: обзор сферы охвата фармакологических и нефармакологических мероприятий.

ВВЕДЕНИЕ: Усталость является весьма распространенным симптомом у людей с множественным склерозом. Он требует тщательной оценки и оперативного вмешательства в целях повышения качества их жизни и общего бремени болезней. Цель этого аналитического обзора состоит в том, чтобы обеспечить всеобъемлющее обобщение и обновление имеющихся данных об эффективности различных фармацевтических и нефармакологических мероприятий в связи с множественным склерозом (МС) усталости. МЕТОДЫ: Для обеспечения транспарентности и качества статей, выбранных для этого аналитического обзора, использовались предпочтительные

Совпадение в аннотации оригинала
INTRODUCTION: Fatigue is a highly prevalent symptom in people with multiple sclerosis. It demands careful assessment and prompt intervention to improve their quality of life and overall burden of disease. This scoping review aims to provide a comprehensive synthesis and update of the existing evidence on the effectiveness of different pharmacological and non…

Усталость и связанное со здоровьем качество жизни пациентов с множественным склерозом.

Множественный склероз - это изнурительное хроническое неврологическое заболевание с различными симптомами. Одной из главных причин этого является усталость, которая оказывает негативное воздействие на физическое функционирование, производительность, общее благосостояние и качество жизни, связанное со здоровьем (HRQOL). AIM: Разоблачение взаимосвязи между усталостью и HRQOL в этой клинической группе населения в Саудовской Аравии, поддержка разработки всеобъемлющих режимов ухода за больными. В трех городах Саудовской Аравии (130 женщин, 71 мужчина) пациенты были приняты на работу в амбулаторные

Совпадение в аннотации оригинала
BACKGROUND: Multiple sclerosis is a debilitating, chronic neurological disease with diverse symptoms. Fatigue is a major aspect of this, impacting negatively on physical functioning, productivity, general well-being and health-related quality of life (HRQoL). AIM: To expose the relationship between fatigue and HRQoL in this clinical population in Saudi Arab…

[Association of inflammation and chronic fatigue syndrome in patients with Parkinson's disease].

OBJECTIVE: To study the prevalence of chronic fatigue syndrome (CFS) and association of CFS with other clinical and neuropsychological manifestations of Parkinson's disease (PD) as well as with serum inflammatory markers and genetic polymorphisms. MATERIAL AND METHODS: The study included 533 patients with PD. All patients underwent clinical, neurological examination and neuropsychological testing using validated questionnaires: MoCA test, HADS, BDI-II, the Fatigue Severity Scale (FSS). Serum concentrations of inflammatory markers (slCAM-1, sVCAM-1, NCAM, CCL5, PAI-1 and MPO) were assessed in …

Effect of propofol and sevoflurane on postoperative fatigue after laparoscopic hysterectomy.

BACKGROUND: Postoperative fatigue syndrome (POFS) is an important factor in postoperative recovery. However, the effect of anesthetic drugs on postoperative fatigue in female patients has been rarely studied. This study compared the effects of maintaining general anesthesia with propofol or sevoflurane on the incidence of POFS in patients undergoing laparoscopic hysterectomy. METHODS: This prospective, single-blind, randomized controlled trial enrolled patients scheduled for laparoscopic hysterectomy. Eligible patients were randomized into the propofol and sevoflurane groups. The primary outc…

Engagement of mental effort in response to mental fatigue: A psychophysiological analysis.

Acute mental fatigue, characterized by a transient decline in cognitive efficiency during or following prolonged cognitive tasks, can be managed through adaptive effort deployment. In response to mental fatigue, individuals can employ two main behavioral patterns: engaging a compensatory effort to limit performance decrements, or disengaging effort, leading to performance deterioration. This study investigated the behavioral pattern used by participants in mental fatigue conditions. Fifty participants underwent a sequential-task protocol with counterbalanced sessions who took place in two sepa…

Vitamin D and Its Role on the Fatigue Mitigation: A Narrative Review.

Vitamin D has historically been associated with bone metabolism. However, over the years, a growing body of evidence has emerged indicating its involvement in various physiological processes that may influence the onset of numerous pathologies (cardiovascular and neurodegenerative diseases, rheumatological diseases, fertility, cancer, diabetes, or a condition of fatigue). This narrative review investigates the current knowledge of the pathophysiological mechanisms underlying fatigue and the ways in which vitamin D is implicated in these processes. Scientific studies in the databases of PubMed,…

Association between cytokines and fatigue in patients with type 1 narcolepsy.

BACKGROUND: Fatigue is a frequent complaint among patients with narcolepsy. Studies have shown that inflammatory cytokines are associated with fatigue in neurological disorders; however, this association has not been identified in patients with type 1 narcolepsy. The purpose of this study was to investigate the potential relationship between cytokines and fatigue in patients with type 1 narcolepsy. METHODS: We investigated the association between 12 inflammatory cytokines and fatigue in 49 patients with type 1 narcolepsy. The Multidimensional Fatigue Inventory-20 was used to assess the fatigu…

Health-Related Quality of Life and Fatigue in Children with Pompe Disease.

OBJECTIVE: Pompe disease is an inheritable metabolic myopathy caused by the deficiency of the lysosomal enzyme acid-⍺-glucosidase. The aim of this study was to investigate self-reported and parent-reported health related quality of life (HR-QOL) and fatigue in children with Pompe disease. STUDY DESIGN: In this cross-sectional study, the validated Child Health Questionnaire and PedsQL Multidimensional Fatigue Scale were used to respectively measure (both self-reported and parent-reported) HR-QOL and fatigue in children with Pompe disease. RESULTS: In total, of 24 patients with Pompe disease (…

A Guided Comparative Analysis of Fatigue Frameworks in Australasian Ambulance Services.

OBJECTIVE: Paramedics work in a complex, unpredictable environment, subject to many external stressors including critically unwell patients, dangerous driving conditions, and prolonged shift work. Paramedic fatigue from these and other occupational demands is well documented. Ambulance services attempt to safeguard paramedics from fatigue using internal policies or procedures - a type of Fatigue Risk Management Systems (FRMSs). This study reviews ambulance service fatigue frameworks to understand the current situation in fatigue management in paramedicine, and to identify fatigue monitoring to…