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Building on Self-Determination Theory to Unravel the Motivational Drivers of Nurses and Rehabilitation Therapists in a Moroccan University Hospital: A Qualitative Study.

Background: Nurses' motivation is essential for ensuring the quality of care and workforce retention. Understanding the underlying psycholog … sed to select 26 participants, including nurse managers (n = 7), rehabilitation therapists (n = 5), pharmacy technicians (n = 4), nurses at the Hematology Department (n = 4), nurses at the Emergency Department (n = 4), and nurses in the outpatient consultation unit of the Otorhinolaryngology Department (n = 2). Data collection was conducted from March to June 2023, fo …

Facilitators and barriers to adherence to severe malaria treatment guidelines in children at Mbale Regional Referral Hospital, Uganda: a health workers' perspective.

BACKGROUND: Malaria is a significant public health concern, particularly in sub-Saharan Africa, where it causes considerable morbidity and mortality. Severe malaria is a major cause of mortality among children under five, contributing to Uganda's high malaria mortality burden. Effective case management of severe malaria is crucial which should be guided by the Uganda clinical guidelines adopted from the World Health Organization. This study explored the barriers and facilitators to healthcare providers' adherence to severe malaria treatment guidelines in children at Mbale Regional Referral hos

Implementation of a large-scale hypertension program in primary health centres in the Federal Capital Territory, Nigeria: an explanatory, sequential mixed-methods study.

INTRODUCTION: To optimise hypertension care cascade, the multilevel Hypertension Treatment in Nigeria (HTN) Program, adapted from the WHO HE … focus group discussions in a subset of PHCs with patients (n=17), community health workers (n=35), pharmacy technicians (n=18) and PHC directors (n=5). Eighteen sites were purposively selected based on facility performance, targeting sites in the top and bottom 12% of blood pressure (BP) control at the end of the HTN Program. Qualitative data were coded, and subtheme …

Developing a mHealth intervention to redesign the current journey for people living with HIV: A qualitative study.

OBJECTIVE: People living with human immunodeficiency virus could particularly benefit from mobile health (mHealth). The objective of the study was to  contribute to the design and development of a new standard of care for people  living with human immunodeficiency virus and the mHealth app needed to  support it by 1) exploring the view of people living with human  immunodeficiency virus and healthcare professionals on the possibilities of  mHealth tools on HIV care, and 2) implementing their feedback into the new  app and into the new journey of people living with human immunodeficiency  virus

Barriers and Consequences of Prior Authorization for Neurologic Medications: A Scoping Review.

IMPORTANCE: Prior authorization (PA) is widely used by insurers to control health care costs and promote high-value care, but it can create significant barriers to accessing medications. This is particularly concerning in neurology, where timely treatment is critical to avoid disease progression and optimize patient outcomes. OBJECTIVE: To assess the consequences, barriers, and facilitators of PA policies affecting access to pharmacologic treatment in 6 common neurologic conditions-Alzheimer disease, Parkinson disease, multiple sclerosis, migraine, cerebrovascular disease, and epilepsy-with f

The response to COVID-19 among drug retail outlets in Indonesia: A cross-sectional survey of knowledge, attitudes, and practices.

BACKGROUND: Pharmacists have been at the frontline of the COVID-19 response in Indonesia, providing medicines, advice, and referral services often in areas with limited healthcare access. This study aimed to explore their knowledge, attitudes, and practices during the pandemic, so that we can be better prepared for future emergencies. METHODS: A cross-sectional online survey of community pharmacists and pharmacy technicians in Indonesia was conducted between July and August 2020. The dataset was analysed descriptively, and logistic regression was used to explore willingness to participate in …

Consensus Guideline for Care of Patients in the Prehospital and Aerospace Settings with Exposures to Hydrazine and Hydrazine Derivatives.

OBJECTIVES: Hydrazine (HZ) and Hydrazine Derivative (HZ-D) exposures pose health risks to people in industrial and aerospace settings. Several recent systematic reviews and case series have highlighted common clinical presentations and management strategies. Given the low frequency at which HZ and HZ-D exposures occur, a strong evidence base on which to develop an evidence-based guideline does not exist at this time. Therefore, the aim of this project is to establish a consensus guideline for prehospital care of patients with exposures to HZ and HZ-Ds. METHODS: A modified Delphi technique was

Health facility assessment of small and sick newborn care in low- and middle-income countries: systematic tool development and operationalisation with NEST360 and UNICEF.

BACKGROUND: Each year an estimated 2.3 million newborns die in the first 28 days of life. Most of these deaths are preventable, and high-quality neonatal care is fundamental for surviving and thriving. Service readiness is used to assess the capacity of hospitals to provide care, but current health facility assessment (HFA) tools do not fully evaluate inpatient small and sick newborn care (SSNC). METHODS: Health systems ingredients for SSNC were identified from international guidelines, notably World Health Organization (WHO), and other standards for SSNC. Existing global and national service

Nurse-driven protocols for febrile pediatric oncology patients.

INTRODUCTION: Infection is a frequent complication experienced by many children with cancer, with potentially life-threatening consequences that may result in hospitalization, prolonged length of stay, and increased mortality. The need for prompt assessment and early intervention for infection is widely recognized by ED staff as best practice; however, the average length of time to antibiotic administration varies widely in published studies. METHODS: An interdisciplinary quality improvement initiative including physician, nursing, and pharmacy leaders was created to streamline the identifica

Easing the burden: exploring the role of long-acting testosterone formulations in gender-affirming care.

INTRODUCTION: Long-acting testosterone formulations are essential but infrequently used for gender affirmation. Although not FDA approved in the United States for gender dysphoria, testosterone undecanoate is a long-acting testosterone formulation administered every 10 weeks. Similarly, Testopel is an FDA-approved testosterone pellet implanted subcutaneously every three to six months, which slowly releases testosterone for a long-acting androgenic effect. METHODS: A retrospective review was conducted between January 2020 and June 2024. Data was collected through the electronic health record u

SARS-CoV-2 Antibody Prevalence Across Unvaccinated Health Care Workers During the COVID-19 Pandemic in Yemen: Cross-Sectional Study.

BACKGROUND: The COVID-19 pandemic presented significant challenges to health care centers across Yemen. The lack of access to COVID-19 vaccines and limited availability of personal protective equipment greatly increased the risk of SARS-CoV-2 exposure among health care workers (HCWs). Only a few studies have examined the seroprevalence and burden of SARS-CoV-2 among Yemeni HCWs. OBJECTIVE: This study aimed to assess the seroprevalence of SARS-CoV-2 and associated risk factors among a cohort of unvaccinated HCWs in Ibb City, the capital of Ibb Governorate, located in the highlands of southwest

Human resources for cancer control in uttar pradesh, India: a case study for low and middle income countries.

For addressing the growing burden of cancer in low and middle income countries, an important first step is to estimate the human resources required for cancer control in a country, province, or city. However, few guidelines are available to decision makers in that regard. Here, we propose a methodology for estimating the human and other resources needed in the state of Uttar Pradesh (UP), India as a case study. Information about the population of UP and its cities was obtained from http://citypopulation.de/. The number of new cancer cases annually for the commonest cancers was estimated from G

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… An oncology ward is a 24-bed in-patient unit for only oncology patients that should be staffed by 15 oncology nurses, 4 oncopharmacists, and 6 pharmacy technicians. … technicians) needed and available. …

An Integrated Health-System Specialty Pharmacy Model for Coordinating Transitions of Care: Specialty Medication Challenges and Specialty Pharmacist Opportunities.

Adherence and persistence to specialty medications are necessary to achieve successful outcomes of costly therapies. The increasing use of specialty medications has exposed several unique barriers to certain specialty treatments' continuation. Integrated specialty pharmacy teams facilitate transitions in sites of care, between different provider types, among prescribed specialty medications, and during financial coverage changes. We review obstacles encountered within these types of transitions and the role of the specialty pharmacist in overcoming these obstacles. Case examples for each type

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… When patients incur a lapse in coverage or an insurance rejection for their medication, pharmacists and pharmacy technicians can efficiently navigate the process of ensuring medication access and affordability. … Acknowledgments The authors would like to acknowledge the pharmacists, pharmacy technicians, and support staff at Vanderbilt Specialty Pharmacy and providers and clinic staff of Vanderbilt University Medical Center for their work in providing exceptional patient care during care transitions. …

Abstracts 12th PCNE working conference 'Partnering for better patient outcomes: challenges and opportunities 3-6 February 2021, University of Basel, Switzerland (was held online).

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… of Pharmacy Technicians, 3 Association of Danish Pharmacies. … This is the first study carried out to specifically analyse how pharmacy technicians contribute to counselling. …

Lecanemab-Monoclonal Antibodies for the Treatment of Early Alzheimer's Disease.

OBJECTIVE: Review the pharmacology, efficacy, and safety of lecanemab, a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody, for the treatment of early Alzheimer's disease (AD). DATA SOURCES: Comprehensive search of Embase, PubMed, International Pharmaceutical Abstracts, Cochrane CENTRAL, Scopus, Web of Science, and Google Scholar were conducted from inception through December 2025. STUDY SELECTION AND DATA EXTRACTION: Phase I-III clinical trials, systematic reviews, and meta-analyses evaluating lecanemab pharmacology, pharmacokinetics, efficacy, and safety were included. Product la

Evaluation of Chromium Picolinate Supplementation and Insulin Requirements in Critically Ill Adults With Type 2 Diabetes Mellitus.

BACKGROUND: Chromium picolinate has been studied as an adjunct to improve glycemic indices in ambulatory type 2 diabetes mellitus, but its role in critically ill patients is unknown. OBJECTIVE: To evaluate whether chromium picolinate supplementation was associated with reduced insulin requirements without worsening glycemic control in critically ill adults with type 2 diabetes mellitus. METHODS: We conducted a single-center retrospective pre-post cohort study of adult intensive care unit patients with type 2 diabetes mellitus or hemoglobin A1c ≥6.5% who received insulin and at least 4 consec

Stevens-Johnson Syndrome And Toxic Epidermal Necrolysis Possibly Related to Daptomycin And Ceftaroline in a Patient With Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia: A Case Report and Brief Review.

Objective: We report a unique case of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) possibly related to administering daptomycin and ceftaroline for persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. We describe treatment strategies and challenges of determining drug causality when multiple antimicrobials are administered. Case: A 78-year-old male developed SJS/TEN during week 6 of daptomycin and ceftaroline therapy. Other antimicrobials administered within the previous 8 weeks included vancomycin, meropenem, piperacillin/tazobactam, levofloxacin, a

Anticholinergic Adverse Effects Associated With Skeletal Muscle Relaxants in the Intensive Care Unit.

Background: Pain is prevalent among critically ill patients and is frequently underrecognized due to sedation and mechanical ventilation. Opioids remain the primary analgesic therapy in the intensive care unit (ICU); however, opioid-related adverse effects have prompted increased adoption of multimodal analgesia strategies. Centrally acting skeletal muscle relaxants, including cyclobenzaprine and methocarbamol, are commonly used as adjuncts, yet data evaluating their anticholinergic adverse effects in critically ill populations are limited. Methods: The primary objective of this study is to de

A Retrospective Chart Review Comparing Long-Term Opioid Prescribing Practices Between Care in the Community and Veterans Affairs Providers.

BACKGROUND: Using Veterans Affairs (VA) clinical practice guidelines as a reference, this study compared long-term opioid prescribing practices and risk mitigation strategies in veterans receiving care at the Greater Los Angeles VA compared with veterans receiving Care in the Community (CITC). A retrospective chart review was performed on 46 CITC patients and a random sample of 50 VA patients who received 90 days or more of an opioid prescription between July 1, 2018, and June 30, 2019, and were followed for 1 year. RESULTS: The 2 populations were prescribed similar opioid treatments, and alt

Tradipitant for Motion Sickness: Expanding the Therapeutic Landscape of NK₁ Receptor Antagonists.

OBJECTIVE: To review the efficacy, safety, and tolerability of tradipitant for the prevention of vomiting induced by motion. DATA SOURCES: A literature search was conducted through PubMed using the following terms: tradipitant, motion sickness, Nereus, and neurokinin-1 (NK-1) receptor antagonist. STUDY SELECTION AND DATA EXTRACTION: Articles describing the pharmacology, pharmacokinetics, efficacy, safety, and/or tolerability of tradipitant were included in this review. DATA SYNTHESIS: Tradipitant is a NK-1 receptor antagonist shown to reduce vomiting due to motion. Clinical trials have demo