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Safety, effectiveness and predictors for early reoperation in therapeutic and prophylactic vertebroplasty: short-term results of a prospective case series of patients with osteoporotic vertebral fractures.

INTRODUCTION: Vertebroplasty (VP) is a cost-efficient alternative to kyphoplasty; however, regarding safety and vertebral body (VB) height restoration, it is considered inferior. We assessed the safety and efficacy of VP in alleviating pain, improving quality of life (QoL) and restoring alignment. METHODS: In a prospective monocenter case series from May 2007 until July 2008, there were 1,408 vertebroplasties performed during 319 interventions in 306 patients with traumatic, lytic and osteoporotic fractures. The 249 interventions in 233 patients performed because of osteoporotic vertebral fra…

Vertebral compression fracture risk after stereotactic body radiotherapy for spinal metastases.

OBJECT: The aim of this study was to identify potential risk factors for and determine the rate of vertebral compression fracture (VCF) afte … rogressions), and sarcoma (9 VBs, 2 fractures, 2 tumor progressions). Fifteen VBs were treated with kyphoplasty or vertebroplasty after SBRT, with 5 procedures done for preexisting VCFs. Tumor progression was noted in 32 locations (26%) with 5 months' median time to progression. At the time of noted fracture progression there was a trend toward higher average …

CyberKnife radiosurgery for malignant spinal tumors: characterization of well-suited patients.

STUDY DESIGN: A prospective interventional case-series study. OBJECTIVE: To provide clinical results of CyberKnife fiducial-free spinal rad … red in one, and another developed spinal instability. These and 2 other patients were stabilized by kyphoplasty. Neurotoxicity or myelopathy was not observed. Local tumor control 15 months after CKRS was 98% (95% CI: 89-99%). Tumor-associated pain was observed in 52 (51%) patients. In these patients the median pretreatment pain score of VAS = 7 (95% CI: 6-7) …

Robotic-Assisted Removal of Intracardiac Cement After Percutaneous Vertebroplasty.

Percutaneous vertebroplasty (PVP) is an increasingly common intervention, and complications resulting from embolization are increasingly observed. We report a case of polymethyl methacrylate (PMMA) embolization resulting in cardiac complications in a frail patient, which was managed with endoscopic robotic-assisted removal of the embolized material.

[Osteoporotic vertebral body fractures of the thoracolumbar spine. Diagnostics and therapeutic strategies].

In cases of severe osteoporosis vertebral body fractures of the thoracolumbar spine can occur without any relevant trauma. Initially, a standardized diagnostic algorithm is recommended to detect acute vertebral body fractures and to be able to interpret the individual fracture stability. Aim of the therapy is to assure a relatively pain-free mobilization while maintaining vertebral spine alignment. A conservative therapy concept is initiated in patients with stable fractures. In cases of persistent pain, reduced mobility or increased kyphotic misalignment minimally invasive cement augmented th

[Assessment of Reduction Abilities of an Expandable Stent in Treating Osteoporosis-Related Fractures of Th/L (Thoracolumbar) Spine].

PURPOSE OF THE STUDY The method of stabilising the osteoporosis-related spinal fractures using an expandable stent (vertebral body stent - V … . DISCUSSION All the authors agree that the method brings immediate analgesic effect, comparable to kyphoplasty or vertebroplasty. In our cohort, good reduction ability of the implant in the middle part of the vertebral body was confirmed. This has been confirmed also by other authors. Nonetheless, at a longer time interval the loss of correction was observed …

Which spinal fixation technique achieves which degree of stability after thoracolumbar trauma? A systematic quantitative review.

BACKGROUND CONTEXT: Unstable traumatic spinal injuries require surgical fixation to restore biomechanical stability. PURPOSE: The purpose o … dy replacement with additional instrumentation, and augmentation techniques, eg, vertebroplasty and kyphoplasty. Minor injuries were generally treated with less invasive surgical methods such as augmentative and posterior approaches. Bisegmental posterior pedicle screw fixation led to stabilization of minor compression injuries, whereas in more severe injurie …

[Effectiveness of long segment fixation combined with vertebroplasty for severe osteoporotic thoracolumbar compressive fractures].

OBJECTIVE: To study the effectiveness of long segment fixation combined with vertebroplasty (LSF-VP) for severe osteoporotic thoracolumbar compressive fractures with kyphosis deformity. METHODS: Between March 2006 and May 2012, a retrospective analysis was made on the clinical data of 48 cases of severe osteoporotic thoracolumbar compressive fractures with more than 50% collapse of the anterior vertebral body or more than 400 of sagittal angulation, which were treated by LSF-VP in 27 cases (LSF-VP group) or percutaneous kyphoplasty (PKP) in 21 cases (PKP group). All patients suffered from sin…

Elective Spinal Transpedicular Ablation of the Basivertebral Nerve of the Vertebral Segment in Adult Spinal Deformity Patients.

BackgroundAblation of the basivertebral nerve (BVNA) innervating the vertebral endplate has become a standard treatment of vertebrogenic chr … f the BVNA, and 1 was an S2 sacral fracture. These VCF patients were treated with vertebroplasty or kyphoplasty and continued preventive care with added teriparatide. At LFU, the VCF subgroup had a modest 6 cm improvement in VAS to 4 cm and continued to have significant severe to moderate disability (Oswestry Disability Index average of 38 points).ConclusionC …

Interventional techniques: evidence-based practice guidelines in the management of chronic spinal pain.

BACKGROUND: The evidence-based practice guidelines for the management of chronic spinal pain with interventional techniques were developed t … nology. For vertebral augmentation procedures, the evidence is moderate for both vertebroplasty and kyphoplasty. The evidence for spinal cord stimulation in failed back surgery syndrome and complex regional pain syndrome is strong for short-term relief and moderate for long-term relief. The evidence for implantable intrathecal infusion systems is strong for s …

Do Hounsfield Units From Intraoperative CT Scans Correlate With Preoperative Values?

BACKGROUND: There is increasing interest in forecasting postoperative complications using bone density metrics. Vertebral Hounsfield unit me … T scans but the studies were not accessible for Hounsfield unit measurement, and 0.7% (2) had prior kyphoplasty wherein the cement prevented Hounsfield unit measurement. Finally, an additional 19% (53) of patients were excluded because the preoperative CT and intraoperative CT were obtained at different peak voltages, which can influence Hounsfield unit measu …

Use of O-arm with neuronavigation in percutaneous vertebroplasty reduces the surgeon's exposure to intraoperative radiation.

IntroductionPercutaneous vertebroplasty is commonly used to treat spinal fractures. The authors compare radiation exposure as potential risk for the surgical team during vertebroplasty guided by O-arm combined with neuronavigation versus vertebroplasty guided by C-arm fluoroscopy.Material and methodsThe clinical material consisted of a group of 29 patients (44 vertebrae) with fractures of the thoracolumbar spine treated with percutaneous vertebroplasty guided by O-arm with neuronavigation. In this new method, the operating room staff leaves the operating room for the duration of the 3D scan of

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… The only available research describes differences between fluoroscopically assisted kyphoplasty and O-arm guided kyphoplasty [ 23 , 24 ]. … Patients were divided into 2 groups: a group of 29 subject to computer navigated kyphoplasty and a control group treated by means of a conventional C-arm controlled kyphoplasty procedure. …

Efficacy and safety of vertebral augmentation techniques in patients with osteoporotic vertebral compression fractures: A single center, retrospective, observational study.

BACKGROUND: Back pain secondary to osteoporotic vertebral compression fractures (OVCF) is a common global health problem that is frequently overlooked. For some patients, conservative management (CM) is inadequate to treat the pain associated with OVCF. This subset of patients are often candidates for interventional vertebral augmentation techniques (VAT). Multiple studies have shown significant pain reduction, height restoration, reduction in hospitalization time, morbidity and mortality in patients treated with VAT as compared with those patients treated with CM. This study examines if the p

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… A comparative study of percutaneous kyphoplasty and conservative therapy on vertebral osteoporotic compression fractures in elderly patients. Int J Clin Exp Med. 2017;10(5):8139–8145. 7. Jin C., Xu G., Weng D., Xie M., Qian Y. … Clinical study with comparisons to kyphoplasty. Technol Health Care. 2017 Aug 9;25(4):739–747. doi: 10.3233/THC-160714. 22. Ould-Slimane M., Petit A., Gille O., et al. …

Osteoporotic vertebral fractures: an update.

INTRODUCTION: Osteoporotic vertebral fractures (OVFs) are the most common type of fragility fractures. They have a significant and usually detrimental impact on the patient's functional status and mortality rate, constituting a substantial burden for the patients, their families, and the healthcare system. This narrative review aims to summarize the current knowledge of osteoporotic vertebral fractures and secondary fracture prevention. METHODS: A comprehensive literature search was conducted across major medical databases, including PubMed, Scopus, and Web of Science. Relevant studies, guide

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… Kyphoplasty and vertebroplasty have been compared in multiple studies. The effects of kyphoplasty and vertebroplasty have been compared in three RCTs [ 45 – 47 ]. Their characteristics are summarized in Table 3 . … Table 3 Summary of randomized studies comparing vertebroplasty to kyphoplasty. …

Long Term Survival of Pathological Thoracolumbar Fractures Treated with Vertebroplasty: Analysis Using a Nationwide Insurance Claim Database.

BACKGROUND: There are still debates on the long-term outcome of treating pathological thoracolumbar fractures, including osteoporosis and oncologic problems, using vertebroplasty. METHODS: We collected 8625 patients with pathological thoracolumbar fractures (ICD-9-CM codes 733.13 combined with 805.2 or 805.4) between the years of 2003 to 2013, from the two million random samples from the National Health Insurance Research Database in Taiwan. Survival analysis was conducted to estimate the mortality risks of different treatments, including vertebroplasty (n = 1389), conventional open surgery (

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… Some researchers have explored the long-term mortality and survival for the osteoporotic vertebral compression fractures treated with vertebroplasty or kyphoplasty compared with conservative treatment, and most found kyphoplasty had better survival than vertebroplasty, and both kyphoplasty and vertebroplasty … Although some research showed both vertebroplasty and kyphoplasty were better than conservative treatment or sham procedures without cement, and kyphoplasty may be better than vertebroplasty in restoring the vertebral height [ 39 ] and possibly giving better survival [ 3 ], other studies [ 40 , 41 ] …

Clinical efficacy analysis of extrapedicular unilateral percutaneous vertebroplasty via the upper edge of the transverse process for lumbar osteoporotic vertebral compression fractures.

ObjectiveTo investigate the clinical effect of vertebroplasty through unilateral upper edge of transverse process in the treatment of lumbar osteoporotic vertebral compression fracture (OVCF), and to explore the surgical indications and operation points of this technique.MethodsNinety patients with osteoporotic vertebral compression fractures of the lumbar spine treated in our hospital from June 2020 to June 2021 were retrospectively analyzed and divided into the experimental group and the control group for vertebroplasty according to the principle of randomization; the experimental group was

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… Bilateral percutaneous kyphoplasty achieves more satisfactory outcomes compared to unilateral percutaneous kyphoplasty in osteoporotic vertebral compression fractures: A comprehensive comparative study. J Back Musculoskelet. 2023;36(1):97–105. 10.3233/BMR-210225 35938239 13. … Percutaneous Kyphoplasty: Is Bilateral Approach Necessary? Spine. 2018;43(14):977–83. 29280933 10.1097/BRS.0000000000002531 23. …

Advancements in metastatic spinal cord compression treatment: a narrative review of innovations, challenges, and future directions.

ObjectiveTo synthesize recent advancements in metastatic spinal cord compression (MSCC) treatment, evaluating their efficacy in improving neurological function, pain relief, survival, and quality of life.BackgroundMSCC is an oncologic emergency caused by the progression of cancer to the spine and is prevalent in approximately 3-5% of all cancer patients, with a relatively higher incidence of breast, prostate, and lung cancers. MSCC can lead to irreversible paralysis due to loss of vital sensory and motor functions, thus requiring an immediate diagnosis and treatment.MethodsA systematic PubMed

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… Anselmetti et al 2010 [ 34 ] | The interventions in this study are vertebroplasty and kyphoplasty | Vertebroplasty is the preferred intervention in the majority of cases. However, kyphoplasty is recommended in certain conditions like large vertebral defects and spinal tumors. … Lieberman et al [ 46 ] | Lieberman et al evaluated kyphoplasty for treating painful osteoporotic vertebral compression fractures. …

Percutaneous vertebral augmentation-pearls and pitfalls.

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… Based on this, guidelines initially did not recommend the use of vertebroplasty and kyphoplasty as an option for the management of painful osteoporotic compression fractures ( 6 ). … Spinal subarachnoid hemorrhage after percutaneous kyphoplasty: a case report and literature review. J Spine Surg 2022;8:491-6. 10.21037/jss-22-60 22. Yuan W, Meng X, Cao W, et al. …

VERTEBROPLASTY IN THE TREATMENT OF VERTEBRAL FRACTURES CAUSED BY PLASMACYTOMA.

The aim of this study was to compare and evaluate clinical results before and after vertebroplasty in the treatment of myeloma-induced vertebral fractures. Success of the surgery was defined by increased or reduced pain intensity before and after the treatment, as assessed using the visual analog scale (VAS). The study was designed as a retrospective-prospective study. The study included 26 patients, 14 women and 12 men. Data on patients treated for myeloma-induced vertebral fractures were collected at the Department of Orthopedics, Osijek University Hospital Centre. The following data were an

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… At present, there is an obvious lack of studies that would draw comparisons between kyphoplasty and other interventions, both invasive and noninvasive. … Current results indicate that kyphoplasty and vertebroplasty provide similar reduction of pain intensity, but that kyphoplasty is also linked to a lower rate of cement leakage, as evident in other studies ( 10 , 16 - 18 ). …

Oncological and functional results of the surgical treatment of vertebral metastases in patients with multiple myeloma".

BACKGROUND: In nearly 30% of patients with myeloma, pathological fractures are found to occur in the spine. If the patients are not treated promptly and satisfactorily, the quality of their lives diminishes. Currently, the standard treatment for metastatic lesions of the spine is radiotherapy, but surgical intervention is becoming more frequent. It is very important to quickly identify metastases and implement surgical treatment before any fracture/s occur. METHODS: Over the period of 2010-2014 in our department, a total of 129 patients were treated for metastatic spinal myeloma. 73 patients

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… Kyphoplasty in the treatment of osteolytic vertebral compression fractures as a result of multiple myeloma. J Clin Oncol. 2002;20:2382–2387. doi: 10.1200/JCO.2002.09.097. 11. Atalay B, Caner H, Gokce C, Altinors N. Kyphoplasty: two years of experience in a neurosurgery department. … Acute versus chronic vertebral compression fractures treated with kyphoplasty: early results. Spine J. 2004;4:418–424. doi: 10.1016/j.spinee.2004.01.003. 26. Lieberman I, Reinhardt MK. Vertebroplasty and kyphoplasty for osteolytic vertebral collapse. …