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A case of Escherichia coli native mitral valve endocarditis complicated by annular abscess and central retinal artery occlusion.

Infective endocarditis (IE) is most frequently caused by gram-positive organisms such as Staphylococci, Streptococci, and Enterococci. IE du … ated with a large annular abscess, which ultimately led to septic emboli causing stroke and central retinal artery occlusion (CRAO), an extremely rare sequela of IE. Definitive diagnosis and mitral valve replacement were delayed by a low initial suspicion for IE, as well as complications including pulmonary decompensation and incidental discovery of a mycotic an …

Ocular massage in central retinal artery occlusion: Monitoring vascular recovery with optical coherence tomography angiography - A case series.

PURPOSE: Central Retinal Artery Occlusion (CRAO) is an ophthalmic emergency with a generally poor visual prognosis. Currently, no universally effective, evidence-based treatment exists, and therapeutic options remain limited. Ocular massage (OM) has been proposed as a potential intervention aimed at dislodging emboli and improving retinal perfusion. Optical Coherence Tomography Angiography (OCTA) is emerging as a valuable imaging tool for assessing retinal microvascular changes in real-time. This study evaluates the role of OM in CRAO management and highlights the utility of OCTA in monitoring…

Central Retinal Artery Occlusion in a 6-Year-Old Child with an Acute Chickenpox Infection: A Case Report.

Background: Central retinal artery occlusion (CRAO) is an ophthalmic emergency attributed to a vessel occlusion with an embolus or a thrombus and may occur during the hypercoagulable state, inflammation, or vasculitis. CRAO may occur in children; however its incidence is very rare. Most pediatric cases have detectable etiologies. Case Presentation: We describe the case of an otherwise-healthy six-year-old female, who presented with the sudden and complete vision loss of the left eye lasting over twelve hours after a six-day chickenpox exanthema, followed by a high fever. All the ophthalmologic…

[Thrombolysis treatment and multi- disciplinary management of central retinal artery occlusion in comparison with traditional ophthalmological treatment options].

BACKGROUND AND PURPOSE: <p>The management of central retinal artery occlusion (CRAO) has long been conservative therapy with limited efficacy carried out in ophthalmology departments together with etiolo&shy;gi&shy;cal investigations lacking a standardised protocol. However, CRAO is analogous to ischemic central nervous system stroke and is associated with increased stroke risk, thus, systemic thrombolysis treatment and multidisciplinary management can be beneficial. Since May 2022, at Semmelweis University CRAO patients diagnosed within 4.5 hours are given intravenous thrombolysis therapy and…

Henle fiber layer hemorrhage associated with combined central retinal vein occlusion and cilioretinal artery occlusion: a case report.

BACKGROUND: The purpose of this study is to describe a patient who experienced simultaneous central retinal vein and cilioretinal artery occlusions, as well as perifoveal hemorrhage in the Henle fiber. CASE PRESENTATION: A 67-year-old Iranian woman presented with a 3-day history of reduced vision in her left eye. Venous tortuosity and retinal hemorrhage were observed in the retina, together with whitened regions around the fovea, consistent with the diagnosis of central retinal vein occlusion in conjunction with cilioretinal artery occlusion. In structural and en face optical coherence tomogr…

Outcomes of hyperbaric oxygen treatment for central and branch retinal artery occlusion at a major Australian referral hospital.

INTRODUCTION: This study analysed the treatment outcomes of patients that received hyperbaric oxygen treatment (HBOT) for retinal artery occlusion (RAO) at the Royal Brisbane and Women's Hospital in Brisbane, Australia between 2015 and 2021. METHODS: Retrospective study from patient records including 22 eyes from 22 patients that received HBOT for either central RAO (17 patients) or branch RAO (five patients). Patients received the Royal Brisbane and Women's Hospital RAO protocol for their HBOT. Analysis included best corrected visual acuity pre- and post-treatment, subjective improvements, s…

Monitoring Delayed Toxoplasmosis-Related Branch Retinal Artery Occlusion Using Widefield en face Optical Coherence Tomography and Multimodal Imaging.

Ocular toxoplasmosis has a known, rare association with acute retinal artery occlusion (RAO). We describe a 21-year-old male who presented with acute focal toxoplasmosis chorioretinitis in the right eye treated with intravitreal clindamycin, intravitreal dexamethasone, and adjunct oral therapy for vision-threatening retinitis with subsequent quiescence. Nine months from his initial presentation, the patient presented with a branch RAO adjacent to an inactive retinal scar in the right eye. Widefield en face structural swept-source optical coherence tomography (SS-OCT) centered on the middle ret…

Retinal vascular morphology and blood flow characteristics of patients with various degrees of intracranial internal carotid artery stenosis.

PURPOSE: To explore the retinal vascular morphology and blood flow characteristics of patients with varying degrees of intracranial internal carotid artery (IICA) stenosis. MATERIALS AND METHODS: A total of 280 eligible patients were divided into non-stenosis (n=39), mild stenosis (n=80), moderate stenosis (n=83) and severe stenosis groups (n=49). Hemodynamic indices of the posterior ophthalmic artery (OA), central retinal artery (CRA) and posterior ciliary artery (PCA) in the dark zone of optic nerve were detected using color Doppler ultrasonography. CRA equivalent (CRAE), central retinal ve…

Similarities and Differences in Systemic Risk Factors for Retinal Artery Occlusion and Stroke: A Nationwide Case-Control Study.

BACKGROUND: Retinal artery occlusion (RAO) has been considered a stroke equivalent. This study compares risk factor profiles for thromboembolism among patients with RAO and stroke, respectively. METHODS: This case-control study is based on 5683 RAO patients entered in the Danish National Patient Register between 1st of January 2000 and 31st of December 2018. Cases were matched on sex, year of birth, and age at event with 28,415 stroke patients. The Danish nationwide registries were used to collect information about age, sex, previous diagnoses, and drug prescriptions. Adjusted conditional log…

Unilateral isolated optic nerve infiltration combined with central retinal artery occlusion in a patient with acute myeloid leukemia.

PURPOSE: To report a case of unilateral isolated optic nerve infiltration combined with central retinal artery occlusion in a patient with acute myeloid leukemia. OBSERVATIONS: A 28-year-old acute myeloid leukemia patient with systemic remission after hematopoietic stem cell transplantation presented with optic nerve infiltration combined with central retinal artery occlusion. Fundus examination showed diffuse papillary swelling with blurred margins and whitening macular with cherry-red spot. CBFβ-MYH11 fusion transcript analysis revealed central nervous system relapse of acute myeloid leukem…

Hyperbaric oxygen treatment for non-arteritic central retinal artery occlusion retrospective comparative analysis from two tertiary medical centres.

OBJECTIVES: To compare the visual outcome of patients treated for non-arthritic central retinal artery occlusion (CRAO) in a medical centre that uses hyperbaric oxygen therapy (HBOT) as part of the standard of care (SOC) to medical centres that does not. METHODS: The study included data from two tertiary medical centres. The medical records of all patients diagnosed with non-arthritic CRAO without a patent cilioretinal artery between January 2010 and December 2018 in two tertiary medical centres were reviewed. RESULTS: One hundred and twenty-one patients were treated by HBOT and 23 patients …

Central retinal artery occlusion as a first sign of atrial fibrillation: A 3-year retrospective single-center analysis.

BACKGROUND: Central retinal artery occlusion ((C)RAO) is known to be associated with stroke and/or atrial fibrillation (AF). Nevertheless, patients often present at the ophthalmologist initially and it is unknown how many of these receive an adequate cardiological/neurological work-up (CWU/NWU), including a 24 h-Holter-ECG. HYPOTHESIS: Hypothesis of this study was that patients with (C)RAO do not undergo CWU on regular basis and that new-onset AF is more often detected in patients with CWU. METHODS AND RESULTS: We performed a retrospective analysis of n = 292 consecutive patients who present…

Relationship Between Macular Ganglion Cell Thickness and Ocular Elongation as Measured by Axial Length and Retinal Artery Position.

IMPORTANCE: Other than nasal moisturizers, no standard-of-care medical therapy exists for epistaxis in hereditary hemorrhagic telangiectasia (HHT). With epistaxis as the greatest cause of morbidity in patients with HHT, there is a need to identify effective topical therapies. OBJECTIVE: To determine the efficacy and safety of an intranasal timolol thermosensitive gel vs placebo thermosensitive gel in treating HHT-associated epistaxis. DESIGN, SETTING, AND PARTICIPANTS: This double-blind, placebo-controlled randomized clinical trial was conducted from October 29, 2019, to May 20, 2020, at a t

Retinal artery occlusion followed by contralateral amaurosis fugax in association with eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome).

PURPOSE: To describe two cases of retinal artery occlusion followed by contralateral amaurosis fugax associated with eosinophilic granulomatosis with polyangiitis (EGPA, formerly known as Churg-Strauss syndrome). OBSERVATIONS: Case 1 is a 57 year-old male who presented with transient vision loss in the right eye two weeks after a cilioretinal artery occlusion in the left eye. Evaluation eventually led to a diagnosis of EGPA. The patient was treated with high-dose steroids followed by systemic immunomodulatory therapy. Vision in the right eye recovered to 20/20 with no further episodes of visi…

Describing a New Mechanism of Retinal Detachment Secondary to Ophthalmic Artery Vasospasm Following Subarachnoid Hemorrhage: An Experimental Study.

BACKGROUND: The pterygopalatine ganglion (PPG) and ophthalmic arteries (OpAs) have important roles in ocular autoregulation and retinal and visual functions. The relationship between PPG neuron density, OpA vasospasm, and retinal detachment in subarachnoid hemorrhage (SAH) has never been studied. METHODS: This study was conducted on 25 rabbits. Five animals were in the control group (GI; n = 5), five in the sham group (GII; n = 5), and 15 in the study group (GIII; n = 15). After injection of 1 cc serum saline into the cisterna magna in the sham group, and autologous blood in the SAH group, th

Сочетание центральной артерии сетчатки и вены с оптическим перинеритом после герпеса дерматита в иммунокомпетентном ребенке.

У 15-летнего здорового мальчика возникла острая и быстро развивающаяся зрительная потеря в левом глазу после герпеса дерматита с комбинированной центральной артерией сетчатки (CRAO) и центральной сетчаткой сетчатки (CRVO), а также оптическим перинеритом. Лабораторные тесты были отрицательными. Несмотря на эмпирическое, интенсивное противовирусное лечение системными кортикостероидами, и зрение не удалось восстановить в поврежденном глазу. Герпес дерматит зостера у иммунокомпетентного человека может быть связан с комбинированным CRAO и CRVO, а также с оптическим перинеритом, что приводит к глубо

Совпадение в аннотации оригинала
A 15-year-old healthy boy developed acute, rapidly progressing visual loss in left eye following herpes zoster dermatitis, with a combined central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO), along with optic perineuritis. Laboratory tests were negative. Despite an empirical, intensive antiviral treatment with systemic corticost…