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Recommendations for Improving Ergonomics in Cleft Palate and Lip Surgery: A Scoping Review.

Introduction: Craniofacial and cleft surgeries demand high precision, often leading to significant ergonomic challenges for surgeons. This review highlights critical recommendations for mitigating musculoskeletal disorders and enhancing surgeon well-being through equipment optimization, posture adjustments, and innovative technologies. Methods: To conduct this scoping review, a search of the literature yielded 18 studies which discuss ergonomics in the realm of cleft lip and palate surgery. Results: Eighteen studies were reviewed. Investigated ergonomic strategies in cleft lip and palate surge

Orthopaedic Manifestations of Neurofibromatosis Type I.

Neurofibromatosis type 1 (NF1) is a congenital disease which is caused by mutations in the NF1 gene on chromosome 17, resulting in an altered function of the neurofibromin protein. Owing to the ubiquitous expression of this protein, this syndrome is associated with pathology in many organ systems of the body, especially the central and peripheral nervous, musculoskeletal, and integumentary systems. This review outlines the common sequelae related to a diagnosis of NF1 and the common treatment approach to each.

[Case report of Ito-syndrome associated with congenital hemihypertrophy from the orthopaedic point of view].

We report on the orthopaedic treatment of a patient with the very rare Ito syndrome and congenital hemihypertrophy. The leading symptom is the lamellar depigmentation of the skin for which it is synonymously called incontinantia pigmenti acromians. Further anomalies are found in the central nervous system, as well as the ocular and the musculoskeletal systems. The treatment of the hemihypertrophy and the coexistent dysplasia of the hip with a combination of intertrochanteric shortening osteotomy and a triple osteotomy are specified and further methods are discussed.

Risk Factors for Musculoskeletal Injuries in Military Recruits: The Impact of Sex, Body Fat Percentage, and Physical Fitness.

INTRODUCTION: Basic military training is crucial for preparing civilians for military life. This period prepares them with physical and cognitive skills required for military service. However, basic military training is marked by a high incidence of musculoskeletal injuries. In addition, female sex has been identified as a risk factor in military training courses, contributing to higher medical treatment costs and reduced operational readiness. OBJECTIVE: To investigate the incidence of musculoskeletal symptoms and injuries in male and female recruits during sixteen weeks of Brazilian Marine

Musculoskeletal senescence: a moving target ready to be eliminated.

Aging is the prime risk factor for the broad-based development of diseases. Frailty is a phenotypical hallmark of aging and is often used to assess whether the predicted benefits of a therapy outweigh the risks for older patients. Senescent cells form as a consequence of unresolved molecular damage and persistently secrete molecules that can impair tissue function. Recent evidence shows senescent cells can chronically interfere with stem cell function and drive aging of the musculoskeletal system. In addition, targeted apoptosis of senescent cells can restore tissue homeostasis in aged animals…

Hyperplasia of the thyroid gland and concurrent musculoskeletal deformities in western Canadian foals: reexamination of a previously described syndrome.

A syndrome of neonatal foals characterized by hyperplasia of the thyroid gland and concurrent musculoskeletal deformities (TH-MSD) has been … of gestation, and whether or not the submission had evidence of a lesion of the thyroid gland, the musculoskeletal system, or other abnormal clinical or postmortem findings. One hundred and fifty-four (5.2%) records indicated the presence of an abnormal thyroid gland. Of these, 79 (2.7%) had additional lesions consistent with the TH-MSD syndrome described in the 1980s, …

Tuberculous Trochanteric Bursitis Mimicking Hydatidosis: A Rare Case Report.

Tuberculous trochanteric bursitis is a rare condition that accounts for less than 2% of musculoskeletal tuberculosis cases, usually diagnosed late because of reduced diagnostic suspicion, and the insidious clinical presentation aspect of musculoskeletal tuberculosis. We describe the case of a 26-year-old male presenting with a slowly enlarging painful mass of the right hip without systemic symptoms. Imaging initially suggested hydatidosis, but aspiration confirmed Mycobacterium tuberculosis. A complete bursectomy combined with antitubercular therapy led to full recovery with no recurrence at t

Medical Treatment in the Arctic: A Retrospective 10-Year Analysis.

INTRODUCTION: Military personnel training and operating on the Arctic battlefield face unique medical challenges because of extreme conditions and demanding training regiments. This study aims to characterize the morbidity patterns among military personnel participating in a Joint Arctic Training exercises conducted by the Netherlands Marine Core. MATERIALS AND METHODS: A retrospective analysis was conducted using Epidemiological Surveillance in NATO-2 (EpiNATO-2) data from Joint Arctic Training exercises spanning from January 2014 to April 2024. Medical registrations were categorized accordi

MRI for evaluation of myeloid sarcoma in adults: a single-institution 10-year experience.

OBJECTIVE: The purpose of this study was to evaluate the utilization and role of MRI in the management of myeloid sarcoma in adults. MATERI … r other myeloid sarcoma-related indications, most commonly in the head and neck (three lesions) and musculoskeletal system (three lesions). The mean size of measurable lesions was 5.6 cm (range, 1-20 cm). Compared with muscle, the lesions were isointense (31/41, 75.6%) or hypointense (10/41, 24.4%) on T1-weighted images and mildly hyperintense (39/41, 95.1%) on T2-weigh …

Effects of Muscles on Bone Metabolism-with a Focus on Myokines.

Skeletal muscles and bones, the largest tissues in the body of a non-obese person, comprise the musculoskeletal system, which allows mobility and protects internal organs. Although muscles and bones are intimately related throughout life, observations during development and aging and in human and animal disuse models have revealed the synchronization of tissue mass such that muscle phenotype changes precede alterations in bone mineral density and strength. This review discussed that mechanical forces, which have been the traditional research focus, are not the only mechanism by which muscle-de…

Temporomandibular Disorders Slow Down the Regeneration Process of Masticatory Muscles: Transcriptomic Analysis.

Background and Objectives: Musculoskeletal injuries represent a pathological condition due to limited joint motility and morphological and functional alterations of the muscles. Temporomandibular disorders (TMDs) are pathological conditions due to alterations in the musculoskeletal system. TMDs mainly cause temporomandibular joint and masticatory muscle dysfunctions following trauma, along with various pathologies and inflammatory processes. TMD affects approximately 15% of the population and causes malocclusion problems and common symptoms such as myofascial pain and migraine. The aim of this…

Orthopaedic Manifestations of Melanoma and Their Management.

Melanoma is an aggressive form of skin cancer associated with significant morbidity and mortality. Although commonly seen in dermatologist c … sy will confirm the diagnosis and assist in determining prognosis. As ambassadors of health for the musculoskeletal system, orthopaedic surgeons may be the first practitioners to encounter a pigmented skin lesion. Acral pigmented lesions should prompt a concern for melanoma with appropriate subsequent steps for management to follow. Finally, it is important for every or …

A case with Behçet's disease involving erosive Metacarpophalangeal joint arthritis: the value of ultrasonography in the diagnosis of an Erosion.

BACKGROUND: Behçet's disease (BD) is a chronic multisystemic vasculitis that may emerge with musculoskeletal system involvements, oral-genital recurrent aphthae, mucocutaneous lesions, and ocular symptoms. Arthritis in BD is usually non-erosive and not related to crippling disease. Erosive arthropathy is a very rare manifestation of BD. CASE PRESENTATION: Herein, we present a 60-year-old male patient suffering from BD for 33 years with erosive arthritis in his second metacarpophalangeal joint. After we assessed his finger by X-ray, we diagnosed erosive arthropathy quickly by musculoskeletal u…

Clinical findings in congenital infection by Zika virus: a retrospective study in a reference hospital in Central-West Brazil.

BACKGROUND: An increased number of congenital Zika virus infections with neurological and musculoskeletal malformations have been diagnosed worldwide, however, there are still several gaps in the knowledge about this infection, its associated mechanism, timing of transmission, and description of throughout findings of signs and symptoms, which is described in this paper. The purpose of this study is to describe aspects of congenital Zika syndrome (CZS) beyond the central nervous system comprising detailed delineation of all the other clinical findings. METHODS: A retrospective research develo

An uncommon disorder with multiple skeletal anomalies: Gorlin-Goltz syndrome.

Gorlin-Goltz syndrome is an uncommon disorder transmitted through autosomal dominant inheritance. This syndrome is characterized by multiple … d neoplasms, it is of paramount importance for pediatricians as well as physicians dealing with the musculoskeletal system to be aware of this rare condition.

[Web-based learning in musculoskeletal ultrasound].

Education and training in musculoskeletal ultrasound (MSUS) comprises attendance at theoretical and practical courses and independent study. Web-based learning as a novel teaching method has previously been described. The present study summarizes normal and pathological findings in a web-based approach using widely accepted guidelines. In a prospective study over a period of 3 years normal and pathological images of the musculoskeletal system have been documented and catalogued. Overall 1240 ultrasound images and 183 ultrasound videos were collected. A total of 14.4% were normal and 85.6% were…

[Fibromyalgia (generalized tendomyopathy) in expert assessment. Analysis of 158 cases].

MEDAS-agencies are medical institutions within the Swiss Disability Insurance, which specialize in assessing the working capacity of candidates who apply for a disability pension. Degenerative and other chronic pain disorders of the musculoskeletal system form the majority of cases that we investigate. Fibromyalgia is one of our most frequent diagnoses (8.6%). We become involved in cases on average 8.5 years after the first onset of painful symptoms and on average 2.5 years after the patients have ceased to work. Our experience, tells us that fibromyalgia is usually associated with psychologic…

Muscle Adverse Events Associated With Inclisiran: Data Mining of FAERS Database and Mendelian Randomization Analysis.

Inclisiran, the first small interfering RNA (siRNA) lipid lowering drug, has reported muscle adverse events (MAEs), but long-term safety is … we used Mendelian randomization (MR) to investigate the causal relationship between inclisiran and musculoskeletal system diseases. Among 4685 adverse event reports of inclisiran, 523 MAEs reports were found. Inclisiran has potential signals in terms of MAEs (ROR: 7.51, 95% CI, 6.86-8.23; IC: 2.75, IC 025 : 2.60). Inclisiran-related MAEs signal intensity was lower than …

The arthritis connection to inflammatory bowel disease (IBD): why has it taken so long to understand it?

Inflammatory bowel disease (IBD) associated arthritis is a subgroup of spondyloarthritis (SpA) that has suffered from lack of recognition in … d almost half of them show subclinical gut inflammation, yet the connection between the gut and the musculoskeletal system has remained a vexing problem. Two publications from Nathan Zvaifler (one in 1960, the other in 1975) presciently described the relationship between the gut and the spine/peripheral joints heralding much of the work present today in laboratories aro …

Причинная роль высокого индекса массы тела в многочисленных хронических заболеваниях: систематический обзор и метаанализ исследований менделианского случайного заболевания.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Ожирение представляет собой всемирную эпидемию, которая связана с многообразием болезней при проведении наблюдений. Цель этого исследования заключалась в обобщении данных, полученных в ходе исследований по изучению случайности (MR) менделий, о взаимосвязи между индексом массы тела (ИОВ) и хроническими заболеваниями. МЕТОДЫ: Пубмед и Эмбаза искали результаты исследований в области ОР в связи с основными хроническими заболеваниями, включая сахарный диабет; заболеваниями сердечно-сосудистой, дыхательной, пищеварительной, мускулоскелетной и нервной систем; и новообразованиям

Совпадение в аннотации оригинала
BACKGROUND: Obesity is a worldwide epidemic that has been associated with a plurality of diseases in observational studies. The aim of this … ease outcomes, asthma, chronic obstructive pulmonary disease, five digestive system diseases, three musculoskeletal system diseases, and multiple sclerosis as well as cancers of the digestive system (six cancer sites), uterus, kidney, and bladder. In contrast, genetically predicted higher adult BMI was associated with a decreased risk of Dupuytren's disease, osteoporosi …