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Prospective investigation of the Controlling Nutritional Status (CONUT) score and clinical course of patients with COPD.

BACKGROUND: The Controlling Nutritional Status (CONUT) score evaluates nutritional status based on the following three indices: serum albumin, total cholesterol, and peripheral blood lymphocyte count. However, the impact of the CONUT score on the clinical course of patients with chronic obstructive pulmonary disease (COPD) has not been fully investigated. METHODS: We conducted an observational study of patients with stable COPD attending our hospital. At enrollment, patients with CONUT scores of ≤1 and ≥ 2 were assigned to the normal and malnourished groups, respectively. The patients' clinic…

Retrospective case-control study of nutritional and respiratory status in children with type III esophageal atresia.

OBJECTIVES: To evaluate the impact of undernutrition in school-aged children born with type III esophageal atresia (EA), and to determine its potential risk factors, including their respiratory history and status assessed by pulmonary function tests at school-age. METHODS: Retrospective multicentre cohort study encompassing patients born between 2008 and 2013 with type III EA included in a national registry. Baseline data, surgical history, and outcomes of patients with or without undernutrition (body mass index [BMI] z-score < -2 SD) at the age of 6-9 years were compared. RESULTS: Of the 21

Association Between Exclusive Breastfeeding, Nutritional Status and Eating Behavior, in Chilean Schoolchildren: A Cross-Sectional Study.

Objectives: The aim of this study was to analyze the association between exclusive breastfeeding (EBF) up to six months and both nutritional status and eating behavior in Chilean schoolchildren aged 5 to 8 years. Methods: A cross-sectional study was conducted involving 109 children aged 8-10 years from three cities in Chile. EBF was assessed retrospectively through caregiver questionnaires. Eating behavior was evaluated using the Spanish version of the CEBQ. Anthropometric measurements (weight, height, and waist circumference) were obtained following a standardized protocol to determine nutrit…

Общее количество антиоксидантов в рационе питания и клиническое состояние пациентов с множественным склерозом.

ЦЕЛЬ: Определение общей способности рациона питания к антиоксидантам (DTAC) у людей с MS (PwMS) и оценка его взаимосвязи с питанием и прогрессированием заболеваний. МЕТОДЫ: Межсекциональное количественное исследование с участием 127 пациентов, набранных в Междисциплинарном центре помощи, исследований и обучения в области нейроиммунологии (СИАТРЕН) (Форталеза, Сеара, Бразилия). Клинические параметры включали в себя клинический фенотип, расширенную шкалу статуса инвалидности (EDSS), мышечную шкалу Совета медицинских исследований (MRC) и оценку магнитного излучения (MRI). Измерения веса и высоты

Совпадение в аннотации оригинала
OBJECTIVE: To identify dietary total antioxidant capacity (DTAC) in people with MS (PwMS) and evaluate its interrelation with nutritional status and disease progression. METHODS: Cross-sectional, quantitative study with 127 patients with MS recruited from the Interdisciplinary Center for Assistance, Research and Teaching in Neuroimmunology (CIAPEN) (Fortale…

Supplementation of Micro- and Macronutrients-A Role of Nutritional Status in Non-Alcoholic Fatty Liver Disease.

Non-alcoholic fatty liver disease (NAFLD) is a condition in which the pathological cumulation of fat with coexisting inflammation and damage of hepatic cells leads to progressive dysfunctions of the liver. Except for the commonly well-known major causes of NAFLD such as obesity, dyslipidemia, insulin resistance, or diabetes, an unbalanced diet and imbalanced nutritional status should also be taken into consideration. In this narrative review, we summarized the current knowledge regarding the micro- and macronutrient status of patients suffering from NAFLD considering various diets and suppleme…

Circulating leptin levels in the assessment of Crohn's disease activity and its relation to nutritional status.

Objective: to evaluate leptin levels and its relation to nutritional status in Crohn's disease (CD). Methods: the study included 154 CD patients and healthy controls. Leptin level was determined before treatment. Nutrition levels were assessed using the Nutrition Risk Screening 2002 (NRS-2002) and Patient-Generated Subjective Global Assessment (PG-SGA). Indicators included body mass index (BMI), mid-arm circumference, the circumference of the upper-arm muscle, triceps skinfold thickness, and circumference of legs. Results: leptin levels differed between CD patients (1,025 ± 874 ng/ml) and cont…

Nutritional Status as a Risk Factor for Doxorubicin Cardiotoxicity in Mexican Children with Acute Lymphoblastic Leukemia.

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer in the world. Doxorubicin (Dox) is a very useful drug in these patients, however, one of the main adverse effects caused by the use of Dox is cardiotoxicity (CT). Protein-calorie malnutrition (PCM) is a factor that, among others, can influence the development of CT due to Dox. The aim of our study was to associate PCM as a risk factor for CT induced by Dox in Mexican children with ALL. We included 89 children with ALL who were treated with Dox, from October 2018 to July 2023, and of whom 14 developed some type of CT, 15 wer

[Oral health conditions and nutritional, functional and cognitive status - An approach to the institutionalized older adult].

INTRODUCTION/OBJECTIVE: Multidimensional geriatric assessment is an important diagnostic method in geriatrics. The objective of this article was to establish the relationship between nutritional, functional, cognitive status and oral health of institutionalized older adults. METHODOLOGY: A cross-sectional observational study was carried out, where 93 institutionalized older adults participated, including oral assessment and Barthel, Minimental, Mininutritional and Yesavage scales. An univariate, bivariate and multivariate analysis was performed at 2care sites in the city of Cali, Colombia. R

Association between muscle quality and nutritional status among community-dwelling older adults: A cross-sectional study.

Background: Decline in muscle quality is associated with poorer health in community-dwelling older adults. Although there is evidence that malnutrition is associated with the decline of muscle quality in older adults, few analyses have considered important factors related to muscle quality. Aim: The purpose of this study was to determine the relationship between muscle quality and nutritional status in community-dwelling older adults, taking into account muscle mass, muscle strength, and amount of physical activity. Methods: This was a cross-sectional study. Data were obtained from a health ch…

Discrete prognostic implication of sarcopenia according to nutritional status in surgically treated patients with hypopharyngeal cancer.

BACKGROUND: Nutritional status and sarcopenia affects the prognosis of head and neck cancers including hypopharyngeal cancer. Hypopharyngeal cancer patients tend to exhibit sarcopenia, which is associated with poor treatment outcomes. This study aims to determine the correlation between nutritional status and sarcopenia, and their prognostic role in surgically treated hypopharyngeal cancer. MATERIALS AND METHODS: Patients who had been diagnosed with squamous cell carcinoma originating from the hypopharynx and underwent surgery between January 2009 and December 2019 were enrolled in this study…

Identification of SIBO Subtypes along with Nutritional Status and Diet as Key Elements of SIBO Therapy.

Small intestinal bacterial overgrowth (SIBO) is a pathology of the small intestine and may predispose individuals to various nutritional deficiencies. Little is known about whether specific subtypes of SIBO, such as the hydrogen-dominant (H+), methane-dominant (M+), or hydrogen/methane-dominant (H+/M+), impact nutritional status and dietary intake in SIBO patients. The aim of this study was to investigate possible correlations between biochemical parameters, dietary nutrient intake, and distinct SIBO subtypes. This observational study included 67 patients who were newly diagnosed with SIBO. Bi…

Evaluation of micronutrient and nutritional status among preschool children in Jordan: results from a Nationwide survey.

BACKGROUND: Jordan faces various malnutrition challenges, including undernutrition, micronutrient deficiencies, overweight, obesity, and diet-related non-communicable diseases. The country has shifted from issues of undernutrition to rising rates of overweight and obesity, while still dealing with micronutrient deficiencies. The 2010 national survey revealed high rates of iron and vitamin D deficiencies among preschool children, with about 20% experiencing vitamin A deficiencies. The goals of the 2019 Jordan National Micronutrient & Nutrition Survey (JNMNS) include assessing feeding practices

Hypovitaminosis D and its relationship with nutritional status and quality of life in patients undergoing haemodialysis.

Objective: to assess the prevalence of hypovitaminosis D in patients undergoing haemodialysis (HD) and to determine its relationship with nutritional status and quality of life (QoL). Material and methods: 120 patients were included in the study. The Malnutrition-Inflammation Score (MIS) was used to detect nutritional risk. QoL was evaluated by Kidney Disease Quality of Life version 1.2 (KDQOL-SF). Patients were stratified into three groups according to their vitamin D status: sufficiency (≥ 30 ng/dl), insufficiency (29-10 ng/dl) and deficiency (< 10 ng/dl). Results: hypovitaminosis D was dete…

Assessing Nutritional Status and Functionality in Geriatric Population of Bangladesh: The Hidden Epidemic of Geriatric Malnutrition.

The average life expectancy of the Bangladeshi population has risen over the last decade due to economic growth and improved medical care. Although the increased number of older adults and their health is a significant concern, there is scarce of data regarding that. A community-based cross-sectional study was conducted to analyze the association between nutritional status and functional ability among selected Bangladeshi geriatric populations living in their homes. Of 400 participants, the prevalence of malnutrition, and people at risk of malnutrition was 25.4% and 58.8%, respectively. Furthe…

Chronic intermittent hypoxia due to obstructive sleep apnea slightly alters nutritional status: a pre-clinical study.

Obstructive sleep apnea syndrome (OSAS) is associated with chronic intermittent hypoxia (cIH) that causes disturbances in glucose and lipid metabolism. Animals exposed to cIH show lower body weight and food intake, but the protein-energy metabolism has never been investigated. Here, to address the gap, we studied the impact of cIH on nutritional status in rats. A total of 24 male Wistar rats were randomized into 3 groups (n = 8): a control group (Ctrl), a cIH group (cIH) exposed to cIH (30 s 21-30 s 5% fraction of inspired oxygen, 8 h per day, for 14 days), and a pair-fed group (PF) exposed to…

Nutritional Status is Associated With Preserved Kidney Function in Patients With Autosomal Dominant Polycystic Kidney Disease.

OBJECTIVE: Malnutrition is a common complication in autosomal dominant polycystic kidney disease (ADPKD). We examined whether nutritional status is associated with the preservation of kidney function, using a cohort of typical ADPKD. METHODS: We enrolled ambulatory ADPKD patients in 9 tertiary medical centers in Korea from May 2019 to December 2021. We excluded patients who were aged less than 18 years, who had known end-stage kidney disease at the time of enrollment, who had a diagnosis of atypical ADPKD, and who were Tolvaptan users. The primary outcome was an estimated glomerular filtratio…

[Physical activity and nutritional status in women with rheumatoid arthritis and sarcopenic phenotype of body composition].

AIM: To assess physical activity (PA) and nutritional status and their relationship with the sarcopenic phenotype of body composition in women with rheumatoid arthritis (RA). MATERIAL AND METHODS: 104 women (mean age 59.5±8.7 years) with RA underwent clinical and laboratory examination, dual-energy X-ray absorptiometry. The level of PA and nutritional status were assessed using the International Physical Activity Questionnaire (IPAQ) and Mini Nutritional Assessment (MNA) questionnaires, respectively. RESULTS: Sarcopenic phenotype was diagnosed in 37.1% of patients. Moderate and low PA levels…

Combined assessment of frailty and nutritional status can be a prognostic indicator after percutaneous coronary intervention.

The cardiac prognosis of patients with frailty and malnutrition remains poorly investigated. This study aimed to investigate the impact of frailty and malnutrition on cardiac prognosis by combining the clinical frailty scale (CFS) and the geriatric nutritional risk index (GNRI) in patients who underwent percutaneous coronary intervention (PCI). In this study, 608 patients who underwent PCI for stable angina pectoris between January 2018 and December 2020 were included. CFS scores of ≥ 4 were defined as high CFS and patients with these scores were considered frail. GNRI scores of ≤ 98.0 were de

Influence of Preoperative Nutritional Status on Patients Who Undergo Upfront Surgery for Esophageal Squamous Cell Carcinoma.

Few studies have focused on preoperative nutritional status of esophageal cancer patients eligible for upfront surgery. We aimed to investigate the association of preoperative nutritional status with prognosis of patients who undergo upfront surgery for esophageal cancer. A total of 274 patients who underwent upfront surgery for esophageal squamous cell carcinoma between January 2012 and December 2016 were eligible. Preoperative nutritional status was evaluated using prognostic nutritional index (PNI) scoring system, nutritional risk screening 2002 (NRS 2002), and controlling nutritional statu…

Preoperative controlling nutritional status score predicts systemic disease recurrence in patients with resectable biliary tract cancer.

INTRODUCTION: This study aimed to evaluate the association between the preoperative Controlling Nutritional Status (CONUT) score, survival outcomes, and recurrence pattern in patients with resectable biliary tract cancer (BTC). METHODS: A total of 224 BTC patients (gallbladder, n = 69; intrahepatic bile ducts, n = 26; perihilar bile ducts, n = 72; distal bile duct, n = 57) who underwent surgery with curative intent were enrolled. The best cutoff point of the preoperative CONUT score in discriminating survival was determined using χ2 scores. The sites of recurrence were subclassified as locore…