Mobility and transport of magnesium in squid giant axons.
1. The Mg content of axons obtained from Loligo forbesi averaged 6.4 +/- 0.8 m-mole/kg axoplasm.2. A small patch of radioactive (28)Mg injected into an axon broadened considerably. A similar patch of (45)Ca showed hardly any broadening. The self-diffusion coefficient of Mg in axoplasm is about 2 x 10(-6) cm(2)/sec which is at least twenty times greater than that of Ca.3. Under the influence of an applied electric field Mg migrated towards the cathode. Its mobility was about half of that of Mg in free solution. This suggests that the concentration of ionized Mg in squid axoplasm is between 2 an
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