Результаты поиска

Studies of the teratogenic potential of exposure of rats to 6000-MHz microwave radiation. I. Morphologic analysis at term.

Thirty-six pregnant Wistar strain albino rats were exposed throughout pregnancy to 6000-MHz microwave radiation at a power density level of 35 mW/cm2 or were used as controls. The irradiation did not cause a significant increase in maternal body temperature as measured by a rectal thermocouple. The rats were randomly assigned to one of four groups: home cage control (5), anechoic chamber control (10), sham-irradiated concurrent control (10), and irradiated (11). All animals were killed on the 22nd day of gestation, and maternal tissues were removed and weighed and maternal blood samples were t

Impact of a Short-Term High-Fat Diet on Lifespan and Tumorigenesis After Early-Life Exposure to Radiation.

INTRODUCTION: Children are highly susceptible to radiation's carcinogenic effects. Lifestyle, in particular, diet-induced obesity (DIO) is closely linked to cancer risk factors. Most prior studies, however, have concentrated on the impact of long-term lifestyle factors. OBJECTIVE: We assessed the impact of a short-term, high-fat diet (HFD) during young or adult on lifespan shortening and tumor development after infant radiation exposure. METHODOLOGY: B6C3F1 male mice were irradiated at 1 week of age with 4 Gy of gamma rays or did not undergo irradiation (0 Gy). After weaning, they were assig…

Photon-counting CT in pediatric patients: A multi-institutional evaluation of protocols and radiation exposure in 4,772 patients.

PURPOSE: The purpose of this study was to provide protocol guidance and evaluate radiation dose levels in pediatric photon-counting computed tomography (PCCT) applications. MATERIALS AND METHODS: This multi-institutional, retrospective study included data from PCCT examinations performed between January 2024 and May 2025 in three medical institutions. Protocols were developed through expert consensus to optimize image quality and minimize motion artifacts and radiation exposure in children. Volume CT dose indexes (CTDIvol, in mGy) and dose-length products (DLP, in mGy·cm) were collected acros…

Calculating the annual excess probability of cancer-related mortality: a case study of ionizing radiation and chemical exposure.

Risk factors for cancer, such as ionizing radiation or chemical exposure, can be managed using risk-based approaches when clearly defined thresholds are absent. When considering different magnitudes of risk, it is crucial to use the same indices and calculations to conduct proper comparisons. This study quantified the annual excess probability of cancer-related mortality by attained age for continuous occupational exposure to ionizing radiation or inorganic arsenic (during a working period at ages between 18 and 64 years), using a calculation method recommended by the International Commission

In utero exposure to ionizing radiation and metabolic regulation: perspectives for future multi- and trans-generation effects studies.

PURPOSE: The radiation protection community has been particularly attentive to the risks of delayed effects on offspring from low dose or low dose-rate exposures to ionizing radiation. Despite this, the current epidemiologic studies and scientific data are still insufficient to provide the necessary evidence for improving risk assessment guidelines. This literature review aims to inform future studies on multigenerational and transgenerational effects. It primarily focuses on animal studies involving in utero exposure and discusses crucial elements for interpreting the results. These elements

A Destroyer of Tissues: A Case of Chronic Low-Dose Radiation Exposure and the Need for Frequent Screening in Exposed Populations.

The long-term effects of low-dose radiation exposure are a topic that has been lightly touched on in medical literature. We present a case of a 66-year-old male, who grew up near uranium mines, with several pathologies that are believed to be well explained by his chronic exposure to low-dose radiation. We postulate that screening for etiologies with known associations with radiation may help avoid long-term complications in at-risk populations.

Solar Ultraviolet Radiation Exposure Among Opencast Miners in Namibia with the Use of Electronic Dosimeters: A Feasibility Study.

Importance: The lack of information on exposure of opencast mineworkers to solar ultraviolet radiation, a group I carcinogen, was addressed. … of valid measurements from nine participants showed the mean total daily personal solar ultraviolet radiation exposure of 1.9 ± 1.0 (1.01-1.57) standard erythemal dose (SED) for site A and 3.4 ± 2.6 (3.39-7.28) SED for site B. Conclusions and Relevance: Personal solar ultraviolet radiation exposure above the occupational exposure limit (OEL) demonstrated the need to …

Tradeoffs between Radiation Exposure to the Lens of the Eyes and Diagnostic Image Quality in Pediatric Brain Computed Tomography.

BACKGROUND: Computed tomography (CT) of the brain is associated with radiation exposure to the lens of the eyes. Therefore, it is necessary to optimize scan settings to keep radiation exposure as low as reasonably achievable without compromising diagnostic image information. The aim of this study was to compare the effectiveness of the five practical techniques for lowering eye radiation exposure and their effects on diagnostic image quality in pediatric brain CT. METHODS: The following scan protocols were performed: reference scan, 0.06-mm Pbeq bismuth shield, 30% globally lowering tube curr…

No increase in translocated chromosomal aberrations, an indicator of ionizing radiation exposure, in childhood thyroid cancer in Fukushima Prefecture.

To investigate the effects of radiation exposure due to the Fukushima nuclear power plant accident, following the disaster Fukushima Prefecture launched thyroid ultrasound examinations of residents who were generally younger than 18 years at the time of the earthquake. As the rate of pediatric thyroid cancer was higher than expected, we conducted biological dose assessment based on the frequency of translocated chromosome (Tr) aberrations using peripheral blood lymphocytes. Tr formation frequency was compared among the thyroid cancer (n = 38, median age 18 years, age range 12-26 years), thyroi…

Occupational exposure to ionizing radiation in medical staff: trends during the 2009-2019 period in a multicentric study.

OBJECTIVES: Health workers exposed to ionizing radiation account for  + 50% of workers exposed to man-made radiation in France. Over the last decade, the use of radiation in medicine has increased due to the introduction of new practices. The EXposition des Professionnels de santE aux RayonnemenTs ioniSants study aims to evaluate and characterize the trends in radiation exposure of health workers in France between 2009 and 2019. METHODS: This retrospective study includes all health workers with at least one dosimetric record in the system for occupational dosimetry registration (Système d'inf…

Relationship between exposure to ionizing radiation and mesothelioma risk: A systematic review of the scientific literature and meta-analysis.

BACKGROUND: Ionizing radiation and mesothelioma have been examined among personnel employed in nuclear power plant and patients treated by external beam radiation therapy (EBRT). The association is still controversial; the purpose of this review is to summarize the scientific evidence published in the literature regarding the relationship between ionizing radiation and incidence of mesothelioma and, if possible, estimating strongness of the association by meta-analysis of extracted data. METHODS: Articles included in the systematic review were retrieved by searching among the three main scien

HLA-E and HLA-F Are Overexpressed in Glioblastoma and HLA-E Increased After Exposure to Ionizing Radiation.

BACKGROUND/AIM: Glioblastoma (GBM) is one of the deadliest human cancers responding very poorly to therapy. Although the central nervous system has been traditionally considered an immunologically privileged site with an enhanced immune response, GBM appears to benefit from this immunosuppressive milieu. Immunomodulatory molecules play an important role in immune tumor-host interactions. Non-classical human leukocyte antigens (HLA) class Ib molecules HLA-E, HLA-F, and HLA-G have been previously described to be involved in protecting semi-allogeneic fetal allografts from the maternal immune res

The neuroprotective effects of icariin on ageing, various neurological, neuropsychiatric disorders, and brain injury induced by radiation exposure.

Epimedium brevicornum Maxim, a Traditional Chinese Medicine, has been used for the treatment of impotence, sinew and bone disorders, "painful impediment caused by wind-dampness," numbness, spasms, hypertension, coronary heart disease, menopausal syndrome, bronchitis, and neurasthenia for many years in China. Recent animal experimental studies indicate that icariin, a major bioactive component of epimedium may effectively treat Alzheimer's disease, cerebral ischemia, depression, Parkinson's disease, multiple sclerosis, as well as delay ageing. Our recent study also suggested that epimedium extr

The effects of acute and chronic exposure to 900 MHz radiofrequency radiation on auditory brainstem response in adult rats.

The aim of this study was to determine the effects of short and long-term RFR exposure on ABR by evaluating lipid peroxidation and antioxidant status in adult rats. Sixty male albino Wistar rats were randomly divided into four groups. S1:1 week sham, S10:10 weeks sham, E1:1 week RFR, E10:10 weeks RFR. Experimental group rats were exposed to RFR 2 h/day, 5 days/week during the test period. Sham rats were kept in the same conditions without RFR. After the experiment, ABRs were recorded from the mastoids of rats using tone burst acoustic stimuli. Biochemical investigations in rat brain and ultras

Occupational exposure to ionizing radiation and risk of lymphoma subtypes: results of the Epilymph European case-control study.

BackgroundEvidence linking risk of lymphoma and B-cell lymphoma subtypes to ionizing radiation is inconclusive, particularly at low exposure levels.MethodsWe investigated risk of lymphoma (all subtypes), B-cell lymphomas, and its major subtypes, associated with low-level occupational exposure to ionizing radiation, in 2346 lymphoma cases and 2463 controls, who participated in the multicenter EpiLymph case-control study. We developed a job-exposure matrix to estimate exposure to ionizing radiation, distinguishing between internal and external radiation, and we applied it to the lifetime occupat

Совпадение в полном тексте источника
… Kusunoki Y Hayashi T Long-lasting alterations of the immune system by ionizing radiation exposure: implications for disease development among atomic bomb survivors Int J Radiat Biol 2008 84 1 14 10.1080/09553000701616106 17852558 9. … Karipidis KK Benke G Sim MR Fritschi L Vajdic C Kricker A Non-Hodgkin lymphoma and occupational radiation exposure assessed using local data Occup Med 2009 59 437 439 10.1093/occmed/kqp096 19578076 14. …

Impact of cardiac resynchronisation therapy on cardiologists' exposure to radiation during implantation of pacemakers and implantable cardioverter-defibrillators.

Cardiologists are among the health professionals that are most exposed to ionizing radiation, but there is no recent study quantifying overe … s and ICDs implanted in a large referral centre over a six months period. The endpoint was operator radiation exposure, assessed using a personal electronic dosimeter located on operator's chest. In total, 169 PM/ICD implantations were analysed, 19 of which included CRT. Compared with 'classical' implantation, cardiologist radiation exposure was 9-fold greater durin …