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A gel-based PCR method to differentiate sheeppox virus field isolates from vaccine strains.

BACKGROUND: Sheeppox (SPP) and goatpox (GTP) caused by sheeppox virus (SPPV) and goatpox virus (GTPV), respectively of the genus Capripoxvirus in the family Poxviridae, are severely afflicting small ruminants' production systems in Africa and Asia. In endemic areas, SPP and GTP are controlled using vaccination with live attenuated vaccines derived from SPPV, GTPV or Lumpy skin disease virus (LSDV). Sometimes outbreaks occur following vaccination. In order to successfully control the spread of the virus, it is essential to identify whether the animals were infected by the field strain and the v…

Laser-Induced Graphene Enabled Highly Sensitive Lumpy Skin Disease Detection and Vaccine Validation.

Lumpy skin disease (LSD), caused by Capripoxvirus, poses significant threats to global livestock due to its high contagion and economic impact. Current diagnostic methods are limited by their dependence on laboratories, while vaccine efficacy monitoring relies on cumbersome virus neutralization tests (VNTs). To address these challenges, a laser-induced graphene (LIG)-based electrochemical immunoassay has been developed for the sensitive detection of LSD and the validation of vaccination. The platform employs recombinant F13L antigen and IgM antibody, configured for dual applications: F13L quan

The Prevalence of Pathogens among Ticks Collected from Livestock in Kazakhstan.

Ticks carry and transmit a wide variety of pathogens (bacteria, viruses and protozoa) that pose a threat to humans and animals worldwide. Th … pectrum of transmissible infections to determine the degree of their infection. Four pathogen DNAs (lumpy skin disease virus (LSDV), Coxiella burnetti, Teileria annulata, and Babesia caballi) were detected by PCR in Dermacentor marginatus, Hyalomma asiaticum, Hyalomma scupense, Hyalomma anatolicum. The infection of ticks Dermacentor marginatus and Hyalomma asiaticum colle …

Humoral and cytokine responses to a heterologous goatpox vaccine in Mithun (Bos frontalis): a longitudinal field study.

INTRODUCTION: Lumpy Skin Disease (LSD), caused by a Capripoxvirus, has caused severe outbreaks among cattle in India. The disease status and vaccine response of Mithun (Bos frontalis), a semi-domesticated bovine species of major socio-economic importance in Northeast India, remain poorly understood. Because sero-epidemiological findings have indicated LSDV exposure in Mithun, preventive interventions are needed. METHODS: We conducted a 12-month longitudinal field study in Nagaland to assess the safety and vaccine-induced immune response of a heterologous goatpox vaccine in seronegative Mithun

Investigation of Comorbidity and Risk Factors Analysis During Lumpy Skin Disease Outbreaks in India.

Lumpy skin disease (LSD) is a re-emerging viral transboundary disease affecting cattle and buffaloes, resulting in a significant socio-economic impact on the affected regions. LSD is primarily transmitted among susceptible livestock through hematophagous vectors, including ticks and flies. Ticks also function as reservoirs for various haemoprotozoan parasites, increasing the likelihood of coinfections in affected animals. This study investigates the comorbidity of LSD and associated risk factors using diverse datasets. A total of 414 samples from LSD-suspected animals were screened for LSD, in

Innate Immune Responses to Wildtype and Attenuated Sheeppox Virus Mediated Through RIG-1 Sensing in PBMC In-Vitro.

Sheeppox (SPP) is a highly contagious disease of small ruminants caused by sheeppox virus (SPPV) and predominantly occurs in Asia and Africa with significant economic losses. SPPV is genetically and immunologically closely related to goatpox virus (GTPV) and lumpy skin disease virus (LSDV), which infect goats and cattle respectively. SPPV live attenuated vaccines (LAVs) are used for vaccination against SPP and goatpox (GTP). Mechanisms related to innate immunity elicited by SPPV are unknown. Although adaptive immunity is responsible for long-term immunity, it is the innate responses that preve…

Evaluation of a Combined Live Attenuated Vaccine against Lumpy Skin Disease, Contagious Bovine Pleuropneumonia and Rift Valley Fever.

The use of effective vaccines is among the most important strategies for the prevention and progressive control of transboundary infectious animal diseases. However, the use of vaccine is often impeded by the cost, a lack of cold chains and other factors. In resource-limited countries in Africa, one approach to improve coverage and reduce cost is to vaccinate against multiple diseases using combined vaccines. Therefore, the objective of this study was to evaluate a combined vaccine for the prevention and control of Lumpy Skin Disease (LSD), Contagious Bovine Pleuropneumonia (CBPP) and Rift Val

Development and evaluation of an experimental inactivated vaccine against lumpy skin disease.

BACKGROUND AND AIM: Lumpy skin disease (LSD), caused by the LSD virus (LSDV), results in severe economic losses, reduced productivity, and restricted livestock trade. Although live attenuated vaccines are available, they pose risks such as viral shedding, recombination, and reversion to virulence. Inactivated vaccines, being safer alternatives, are particularly suitable for disease-free regions. This study aimed to develop an inactivated oil-adjuvanted vaccine using a local LSDV isolate and evaluate its immunogenicity and protective efficacy in rabbits. MATERIALS AND METHODS: Scab samples wer

[Biological characteristics and permissiveness to viruses of diploid kidney cells strain from the bat Nathusius' pipistrelle (Pipistrellus nathusii Keyserling & Blasius, 1839; Chiroptera: Microchiroptera: Vespertilionidae)].

INTRODUCTION: Bats are an epidemiologically important natural reservoir of viruses of various taxonomic groups, including causative agents of especially dangerous infections of humans and animals. Considering the relevance of arbovirus infections, it seems advisable to study the spectrum of the sensitivity of cells derived from bats inhabiting and migrating on the territory of the Russian Federation to causative agents of vector-borne diseases of animals.The study aimed to obtain a diploid strain of cells from renal tissue of bats Pipistrellus nathusii and to investigate its biological charact

Integumentary System

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A review of feline infectious peritonitis virus infection.

Feline infectious peritonitis (FIP) is an infectious disease characterized by non-specific laboratory changes and clinical signs. Clinical symptoms include anorexia, jaundice, fever, and weight loss. Moreover, some lesions are found in the digestive and respiratory systems. FIP, whose virulence varies, cannot be distinguished using several diagnostic methods. Moreover, feline coronaviruses (FCoVs) can be classified into two serotypes based on differences in their amino acid sequences, spike (S) protein sequences, and antibody (Ab) neutralization. There are two pathotypes, namely those caused b

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… Molecular detection of lumpy skin disease virus in Malaysia 2021. Int. J. Infect. Dis. 2022;116:S1–S130. 69. Fischer Y, Ritz S, Weber K, Sauter?Louis C, Hartmann K. …

Chest and Mediastinum

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Hematopoietic Tumors

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C

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Hematopoietic Tumors

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Р

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Diseases of the Nervous System

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Hematopoietic Tumors

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61st Annual Conference of Indian Society of Gastroenterology, Virtual Diamond Jubilee ISGCON 2020, 19-20th December 2020.

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Abstracts - IANCON 2025

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