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Oral cancer therapy: policy implications for the uninsured and underinsured populations.

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… A total of 26 states have enacted oral chemotherapy access laws: Oregon (2008), Indiana (2009), Iowa (2009), Hawaii (2009), District of Columbia (2009), Vermont (2010), Connecticut (2010), Kansas (2010), Colorado (2010), Minnesota (2010), Illinois (2011), New Mexico (2011), Texas (2011), New York (2011 …

Abstracts From JADPRO Live at APSHO 2015.

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… Bringing Quality Into Your Practice Laura Mulka, APRN, AOCN, ACHPN, Connecticut Multispecialty Group, Wethersfield, CT As professionals, we pride ourselves on delivering high quality care. … Stricker, PhD, University of Pennsylvania, Philadelphia, PA, Amanda Seltzer, MSW, University of Connecticut, Storrs, CT, Karen Hammelef, DNP, RN, On Q Health, Dearborn, Michigan, SarahLena Panzer, BS, Carevive Systems, Philadelphia, Pennsylvania, and Ellen Dornelas, PhD, Hartford Hospital, Hartford, …

Surveillance for Violent Deaths - National Violent Death Reporting System, 39 States, the District of Columbia, and Puerto Rico, 2018.

PROBLEM/CONDITION: In 2018, approximately 68,000 persons died of violence-related injuries in the United States. This report summarizes data … n 2018. Data were collected from 36 states with statewide data (Alabama, Alaska, Arizona, Colorado, Connecticut, Delaware, Georgia, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Oregon, Rhode Island, S …

The End-of-Life Experience of Patients With Rare Cancers and Their Caregivers.

Little is known about the end-of-life (EOL) experience of patients with rare cancers (PRC) or their caregivers. From September 2002 to August 2008, 618 stage IV cancer patients [195 PRC and 423 patients with common cancers (PCC)] and their caregivers participated in an interview-based cohort study. Patients were interviewed about EOL preferences, planning, medical care, and followed until death. Interviews with caregivers at baseline assessed caregiver mental and physical health; and postmortem, assessed EOL patient care. PRC were four times more likely than PCC to be receiving both radiation

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… Non-tertiary centers included Veterans Affairs Connecticut Healthcare System, West Haven, (CT); Parkland Hospital Palliative Care Service, Parkland Health and Hospital System; and New Hampshire Oncology-Hematology, Hookset (NH). …

Connect MM Registry as a national reference for United States multiple myeloma patients.

BackgroundThe Surveillance, Epidemiology, and End Results (SEER) database and National Cancer Database (NCDB) show improved overall survival (OS) in patients with multiple myeloma (MM) over the last 15 years. This analysis evaluated the validity of the largely community-based Connect MM Registry as a national reference for MM.MethodsBaseline disease characteristics and survival in US newly diagnosed MM patients were examined using the Connect MM Registry as well as SEER and NCDB databases. Baseline characteristics predictive of longer survival in Connect MM were also identified.ResultsAs of Fe

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… SEER and NCDB patients with MM MM patient data were derived from 9 population‐based cancer registries from the SEER‐9 (1975‐2015) areas, which include 9.4% of the US population: San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta. …

Applications of bio-enhanced cementitious composites for sustainable building materials: emission-reduction and carbon-sequestration pathways.

Ampligen [polyI:polyC12U] is a mismatched double-stranded RNA that acts by inducing interferon production (immunomodulator) and by activatin … nts currently on antiretroviral therapy and at risk of viral relapse will be enrolled at centres in Connecticut, New York, Florida and California. A second phase IIb study evaluating the effect of Ampligen on structured treatment interruptions (STI) is also underway. Final results from this study were reported in December 2002. NIH sponsored studies of potent …

Cost Implications of Comorbidity for Autologous Stem Cell Transplantation in Elderly Patients with Multiple Myeloma Using SEER-Medicare.

Comorbidity is more common in older patients and can increase the cost of care by increasing toxicity. Using the SEER-Medicare database from 2000 to 2007, we examined the costs and life-year benefit of Auto-HSCT for MM patients over the age of 65 by evaluating the difference over time relative to comorbidity burden. One hundred ten patients had an Auto-HSCT in the early time period (2000-2003) and 160 in the late time period (2004-2007). Patients were divided by a Charlson Comorbidity Index (CCI) of 0 or greater than 1 (CCI1+). Median overall survival was 53.5 months for the late time period p

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… Data Source SEER registries include the Alaska Native Tumor Registry, Arizona Indians, Cherokee Nation, Connecticut, Detroit, Georgia (Atlanta, Greater Georgia, and Rural Georgia), California (Greater Bay Area Cancer Registry, Los Angeles, and Greater California), Hawaii, Iowa, Kentucky, Louisiana, …

A retrospective study to evaluate the time burden associated with outpatient red blood transfusions indicated for anemia due to concomitantly administered chemotherapy in cancer patients.

PurposeAnemia in cancer patients can be treated with red blood cell (RBC) transfusions. The patient burden associated with a treatment in terms of total time spent is an important factor to consider when measuring the benefits and challenges of a therapy. This study estimates the time-related patient burden associated with outpatient RBC transfusion.MethodsA retrospective chart review of outpatient cancer patients receiving a RBC transfusion was conducted at 10 US centers. RBC transfusion time was measured as time elapsed from pre- to post-transfusion vital sign assessment and from transfusion

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… | Urological | 3 (2.7 %) | | Non-Hodgkin’s lymphoma | 23 (20.9 %) | | Multiple myeloma | 7 (6.4 %) | | Chronic lymphocytic leukemia | 2 (1.8 %) | | Other | 13 (11.8 %) | | Unknown a | 1 (0.9 %) | | Study sites A total of 10 US sites from different states (Kentucky, Ohio, California, Connecticut …

Оленепробиваемые потенциальные возможности и результаты МРТ в случае пациентов с множественным склерозом: перекрестное исследование.

Фон: Олокационная дисфункция (ОД) является недооцененным симптомом множественного склероза (МС). Множественные факторы могут играть определенную роль в ОР, сообщаемом пациентами, такими, как постоянное воспаление центральной нервной системы (СНС), повреждение обонятельных ламп в результате демиелиции и наличие таблеток в мозговых зонах, связанных с обонятельной системой. Действительно, исследования в области нейроимации в MS показали четкую связь ОР с числом и активностью связанных с MS таблеток в фронтальных и временных областях мозга. Однако в этих исследованиях использовались только психофи

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… The most reliable psychophysical tests for evaluating human olfaction in a clinical setting are the University of Pennsylvania Smell Identification Test, the Connecticut Chemosensory Clinical Research Center Test, and the Sniffin’ Sticks Test. …

Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing.

Given the worldwide popularity of hair dyeing, there is an urgent need to understand the toxicities and risks associated with exposure to chemicals found in hair dye formulations. Hair dyes are categorized as oxidative and nonoxidative in terms of their chemical composition and ingredients. For several decades, the expert panel's Cosmetic Ingredient Review (CIR) has assessed the safety of many of the chemicals used in hair dyes; however, a comprehensive review of hair dye ingredients and the risk of exposure to hair dyeing has not been documented. Herein, we review the safety of the various ch

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… Use of hair colouring products and breast cancer risk: a case-control study in Connecticut . European journal of cancer (Oxford, England: 1990) 2002 , 38 ( 12 ), 1647 – 52 . 10.1016/S0959-8049(02)00138-7 . 12142056 Nasca P. C. ; Baptiste M. S. ; Field N. A. ; Metzger B. B. ; DeMartino R. … Hair-coloring product use and risk of non-Hodgkin’s lymphoma: a population-based case-control study in Connecticut . American journal of epidemiology 2004 , 159 ( 2 ), 148 – 54 . 10.1093/aje/kwh033 . 14718216 Zhang Y. ; Sanjose S. D. ; Bracci P. M. ; Morton L. …

Association of Wnt Inhibitors, Bone Mineral Density and Lifestyle Parameters in Women with Breast Cancer Treated with Anastrozole Therapy.

AimTo determine the levels of Wnt inhibitors in patients treated with aromatase inhibitors (AIs) prior to therapy and to investigate their association with bone mineral density (BMD) and lifestyle parameters.Methods137 breast cancer patients were divided into a group treated with 1 mg of anastrozole and a group w/o anastrozole therapy. Serum concentrations of sclerostin and dickkopf1 (DKK1) were measured by ELISA. BMD was measured by dual-energy X-ray absorptiometry (DXA). Lifestyle factors were investigated by a self-reported questionnaire.ResultsSclerostin was significantly higher in the AI-

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… Wu (University of Connecticut, Farmington, CT, USA) for improving the use of English and organization of the text. Author Contributions Conceptualization, R.S., I.B.Ć. and M.S.; Formal Analysis, K.K.; Data Curation, K.B., L.K., T.K., N.R.L., V.Š. and S.T. …

Assisted Reproductive Technology Surveillance - 
United States, 2013.

PROBLEM/CONDITION: Since the first U.S. infant conceived with assisted reproductive technology (ART) was born in 1981, both the use of ART a … Puerto Rico to 7,688 in DC). ART use exceeded the national rate in 13 reporting areas (California, Connecticut, Delaware, Hawaii, Illinois, Maryland, Massachusetts, New Hampshire, New Jersey, New York, Rhode Island, Virginia, and DC). Nationally, among ART transfer procedures in patients using fresh embryos from their own eggs, the average number of embryos …

Suicides among Danish cancer patients 1971-1999.

Compared to the general population, the suicide risk among Danish cancer patients diagnosed in 1971-1986 was increased by 50% for men and 30% for women. We updated the earlier study to evaluate both long-term and recent trends in the suicide risk. Cancer patients with a first cancer diagnosed between 1971 and 1999 in Denmark were followed-up for completed suicide through 1999. Excluding nonmelanoma skin cancer, 564 508 cancer patients were included and 1241 suicides observed. Both the standardised mortality ratio (SMR) of suicide relative to the general population and the suicide rates were an

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… J Pain Symptom Manag 22(1): 544–553 Fox BH, Stanek EJ, Boyd SC, Flannery JT (1982) Suicide rates among cancer patients in Connecticut. J Chron Dis 35: 89–100 Harris EC, Barraclough BM (1994) Suicide as an outcome for medical disorders. …

Временные тенденции и различия в показателях смертности от сердечно-сосудистых заболеваний среди взрослых с множественными миеломами в Соединенных Штатах, 1999-2023.

Новелловые лечебные агенты существенно улучшили выживание многих миэлома (ММ), в результате чего сердечно-сосудистые заболевания (КВД) стали основной причиной смертности, не связанной с раком. Потому что MM в основном затрагивает пожилых людей (средний возраст) 69 ) при повышенном сердечно-сосудистом риске мы сосредоточили внимание на взрослых ≥ 45 Годы. Комплексные национальные данные о временных тенденциях и демографических диспропорциях в смертности, связанной с КЖР, среди пациентов с ОМ остаются ограниченными. Methods Мы провели ретроспективный анализ с использованием данных базы данных CD

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… Conversely, several states maintained long-term declines throughout 1999–2023, including New York, Connecticut, Missouri, West Virginia, Alabama, and Ohio. … Several states demonstrated significant late-2010s increases (Illinois, South Carolina, Oklahoma, Maryland, Minnesota, Wisconsin, Virginia, Mississippi), while others sustained long-term declines (New York, Connecticut, Missouri, West Virginia, Alabama, Ohio). …

The ASH Research Collaborative Sickle Cell Disease Research Network: past, present, and future.

AbstractHistorically, sickle cell disease (SCD) has been overshadowed by progress in other hematologic disorders, but recent advances are reshaping its clinical and research landscape. Despite SCD reducing life expectancy by >20 years even with optimal care, transformative initiatives are fostering hope for improved outcomes. The American Society of Hematology (ASH) established the ASH Research Collaborative Sickle Cell Disease Research Network as a comprehensive program to revolutionize SCD research in the United States. This Network comprises a collection of innovative, research-focused coop

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… Therapeutics, bluebird bio, Chiesi, Editas, Fulcrum, Genentech, GlaxoSmithKline, Guidepoint, Hema Biologics, Hemanext, Novo Nordisk, Octapharma, Pfizer, Protagonist, Roche, Sanofi, and Vertex; and receives research funding from Afimmune, Agios, American Society of Hematology, Centers for Disease Control, Connecticut …

Характеристики использования веществ среди лиц с проблематичным использованием порнографии: обзор сферы охвата.

Потребление порнографии является весьма распространенным явлением в развитых странах, при этом исследования показывают, что 70% мужчин и женщин 40% За последний год порнография рассматривалась женщинами. Использование психоактивных веществ у лиц с проблематичным использованием порнографии (ППУ) является областью, заслуживающей дальнейшего изучения в связи с возможностью его совокупного негативного воздействия, включая риск наркомании и потенциальное негативное воздействие на психическое и эмоциональное здоровье. В настоящем аналитическом обзоре рассматриваются модели потребления веществ и связ

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… watching pornography) Mean age 33.9 years (SD = 8.53), male only Demographic, psychiatric, and substance use comorbidities N Problematic pornography use (PPU) Y Bivariate analysis, regression analysis 8 Stefanovics 2024 APT Foundation for treatment of substance use disorder, headquartered in New Haven, Connecticut …

Global Budget Revenue Model and Care for Patients Receiving Chemotherapy.

ImportanceMaryland's Global Budget Revenue (GBR) model provided fixed global payments to hospitals, aiming to control revenue growth while improving care quality. The implications of GBR implementation in 2014 for cancer care have not been robustly evaluated.ObjectiveTo examine the association between GBR implementation and subsequent changes in episode-based Medicare payments, hospital utilization, and quality of care among Medicare beneficiaries undergoing systemic therapy for cancer.Design, setting, and participantsThis cohort study used a difference-in-differences approach to compare chang

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… We included Medicare beneficiaries in Maryland and 11 control states: Connecticut, Delaware, Illinois, Massachusetts, Michigan, New Jersey, New York, Ohio, Rhode Island, Vermont, and West Virginia. …

Глобальное исследование моральной модели популяризации между полами, религиями и культурами.

ПАУ) или самодостаточной зависимости (т.е. СПА) от порнографии. Несмотря на глобальную доступность порнографии и недавнее официальное признание ППУ как проявления навязчивого сексуального поведения, эти проблемы по-прежнему плохо понимаются, главным образом из-за отсутствия тщательных исследований, выходящих за рамки небольших однородных образцов. В целях устранения этого пробела и предоставления надежных и общеизвестных доказательств мы проверили применимость Моральной модели использования порнографии среди различных групп населения. Эта модель показывает, что у людей возникают проблемы с исп

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… MNP discloses that he has consulted for and advised Baria-Tek and Boehringer Ingelheim; been involved in a patent application with Yale University and Novartis; received research support from the Mohegan Sun Casino and the Connecticut Council on Problem Gambling; consulted for or advised legal, non-profit …

Exploring social determinants of health on chemotherapy-induced peripheral neuropathy severity in ovarian cancer: An integrative review.

Ovarian cancer remains a significant public health concern for women despite advancements in cancer management. Despite comprising only 2.5 % of cancers in women, ovarian cancer ranks as the fifth leading cause of cancer-related deaths among women, with patients frequently receiving late diagnoses. Chemotherapy, a primary treatment, frequently causes chemotherapy-induced peripheral neuropathy (CIPN), affecting over 60 % of patients and leading to severe sensory, motor, and autonomic nerve impairments. This often necessitates dosage reduction or discontinuation of treatment, thereby increasing

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… . | Strengths • The Women’s Activity and Lifestyle Study in Connecticut randomized clinical trial, the largest randomized study of exercise among ovarian cancer patients, uniquely focused on the impact of exercise on CIPN. …

Расовые различия в выживании нескольких миелом: ассоциации с трансплантацией стволовых клеток, страхованием и расширением сети медицинских учреждений.

На уровне населения чернокожие пациенты с множественной миеломой (ММ) могут выжить хуже, чем белые. Авторы изучили вопрос о том, как автологическая трансплантация стволовых клеток (ASCT), страхование и расширение сети " Медикэйд " связаны с расовыми различиями в общем уровне выживания (rwOS) в реальном мире. МЕТОДЫ: Данные, полученные 4932 больные MM (MM)24% Блэк) в Флатиронской базе данных исследований в области здравоохранения анализировался с использованием моделей " Кокс регрессиал " (rwOS), " Файн энд срей " (ASCT) и " политомная регрессия " (страхо

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… Abbreviations: aOR, adjusted odds ratio; NA, not applicable. a States (including the District of Columbia) in the study that expanded Medicaid in the 2011–2021 study period: Arkansas, Arizona, California, Colorado, Connecticut, Delaware, Hawaii, Iowa, Idaho, Illinois, Indiana, Kentucky, Louisiana, Massachusetts …