Результаты поиска

Vision-Threatening Complications of Soft Tissue Fillers: A Report by the American Academy of Ophthalmology.

PURPOSE: To review evidence on ocular complications of injectable soft tissue fillers, identify features associated with risk for vision los … ad in 56 cases (25%); glabella in 26 cases (12%); temple in 21 cases (9%) frontal in 17 cases (7%); nasolabial fold in 9 cases (4%); face in 2 cases; periocular in 2 cases; and lip, eyebrow, cheek, and upper eyelid in 1 case each. The central and upper midface (nose, forehead, glabella, frontal) were the most common sites (189 cases, 84%). The most common therape …

Rates of Vascular Occlusion Associated With Using Needles vs Cannulas for Filler Injection.

IMPORTANCE: Soft-tissue augmentation with skin fillers can be delivered with needles or microcannulas, but unwanted vascular occlusions are … n per week, the odds of occlusion decreased by 1%, and 85% of occlusions had no long-term sequelae. Nasolabial folds and lips were most likely to be occluded, with mean severity level of occlusions highest at the glabella. CONCLUSIONS AND RELEVANCE: In this cohort study, filler injections with either needles or cannulas were associated with a very low risk of in …

Multiple (familial) trichoepitheliomas: a clinicopathological and molecular biological study, including CYLD and PTCH gene analysis, of a series of 16 patients.

Multiple familial trichoepitheliomas (MFT) constitute an autosomally inherited syndrome possibly related to Brooke-Spiegler syndrome (BSS). … tomatic nodules preferentially located on the face, being especially prominent and confluent in the nasolabial folds and inner aspects of the eyebrows. A total of 66 conventional trichoepitheliomas (TEs) were studied microscopically. Aside from typical features of TE, some also exhibited variant morphological patterns including areas reminiscent of other benign a …

Complications and Litigation Associated With Injectable Facial Fillers: A Cross-Sectional Study.

PURPOSE: Soft-tissue injectable fillers are a popular treatment option for patients seeking minimally invasive facial rejuvenation. The use … . The most common locations for complications were the cheek (915 [32.5%]), lips (503 [17.9%]), and nasolabial fold (412 [14.6%]). The commonly reported adverse events were swelling (1,691 [60.1%]), nodule (948 [33.7%]), and pain (636 [22.6%]). Severe complications included intra-arterial injections resulting in necrosis and visual symptoms (eg, blurred vision an …

High-tech facelift.

Recent technological advances in our specialty have made us reappraise the way we approach facial rejuvenation. Some of these technological … newly adapted concepts are used for the brow, glabella, tear trough deformity, cheeks, lips, chin, nasolabial folds, marionette lines, and other areas of soft tissue depressions apparent before or after the lifting procedures. This has allowed us to restore the tridimensional volume and treat the soft tissue atrophy. Patients with significant skeletal soft tissu …

[Relationship between patients' sensitivity to moxibustion stimulation and clinical effect in the treatment of peripheral facial palsy].

OBJECTIVE: To compare the outcome difference between the heat-sensitive and non-sensitive moxibustion stimulation of Yifeng (TE 17) in the t … rked asynersis, asynersis and normal, respectively. In the light of resting posture of the eye, the nasolabial fold and mouth corner, 0, 1, and 2 points indicate severe, mild dissymmetry and normal, separately. In evaluation of the therapeutic effect, twenty points (at most) indicate cured, 17-19 points marked improvement; 14- 16 points improved, and < or = 13 po …

Clinical Outcomes and Complications Associated with Fractional Lasers: A Review of 730 Patients.

BACKGROUND: Fractional lasers were introduced to provide increased safety, while maintaining high efficacy and patient satisfaction. Patient … r skin type was related to the frequency of complications. Improvement in skin condition (wrinkles, nasolabial folds and pigment) was rated by a technician before and after treatment using a Likert scale, 0-5, with 0 being no change and 5 being the most improvement. RESULTS: Seven hundred thirty patients underwent procedures using fractional lasers in our center …

An interesting case of pachydermoperiostosis with idiopathic myelofibrosis associated with monosomy 22.

A 24-year-old man was referred to our clinic in August 2003 with complaints of weakness, dizziness, and bilateral knee pain of 3 years' dura … berg DL. Nail abnormalities: clues to systemic disease. Am Fam Physician 2004; 69: 1417-1424). Deep nasolabial folds were seen on the face. Skin hypertrophy, cutis verticis gyrata, and seborrhea on the face were also observed. The patient also complained of hyperhidrosis. Examination of the cardiovascular system was normal. There was bilateral swelling of the ank …

[Clinical and genetic analysis of a Chinese pedigree affected with Vissers-Bodmer syndrome due to variant of CNOT1 gene and a literature review.].

OBJECTIVE: To investigate the clinical and genetic characteristics of a family with Vissers-Bodmer Syndrome (VIBOS) and to review the releva … ale, presented with short stature, distinctive facial features (esotropia, hypertelorism, prominent nasolabial folds), webbed neck, clinodactyly, and intellectual disability. WES revealed that she has carried a heterozygous c.736delG (p.V246*) variant of the CNOT1 gene, which was unreported previously. The proband's father exhibited borderline intellectual functi …

The potential of four-dimensional (4D) ultrasonography in the assessment of fetal awareness.

AIM: The aim of the study was to observe different expressions and movements of a fetal face during investigation of fetal behavior in the s … ements of the following fetal face structures were analyzed: forehead, brows, nasal soft tissue and nasolabial folds, upper lip, oral cavity and tongue, lower lip and chin, eyelids and eyes, mouth and mouth angles, and facial expression. 4D ultrasonography allowed in utero observations of fetal facial expressions such as smiling, yawning, and swallowing. RESULTS …

Cosmetic Injectable Treatments Improve Quality of Life in Patients With Multiple Serious Medical Comorbidities.

Full facial rejuvenation with multi-modal cosmetic treatments can improve quality of life, leading to improvement in confidence and psychological function. These combination treatments are frequently administered at the same or sequential sessions and include neuromodulators and fillers. In patients with significant recent weight loss and other medical comorbidities, these treatments can help restore self-confidence and provide the encouragement they need to continue treatment for their comorbidities. We present a case report of a 71-year-old woman who experienced significant weight loss of 40

Совпадение в полном тексте источника
… Areas treated included the cheeks, jawline, and nasolabial folds (Figure 2 ). … Figure 2 71-year-old woman after three calcium hydroxyapatite treatments to the cheeks, jawline, and nasolabial folds To assess her quality of life after this full facial multi-modality treatment, the patient filled out baseline and post-treatment FACE-Q aging appraisal, appearance-related psychological …

Acquired Cutis Laxa on the Upper Eyelids and Earlobes: A Case Report and Literature Review.

Acquired cutis laxa is a rare disease. Owing to few reports on the condition, no statistical data have been produced. Cutis laxa is characterized by drooping skin, caused by decreased levels of dermal elastin, leading to reduced skin elasticity. The disease usually emerges on the neck or trunk and spreads throughout the body; however, it rarely involves the extremities. 2 Moreover, cases localized to the face are rare. The objective of this clinical case report was to highlight this unusual disease in a 24-year-old female, with localization on the face and neck. The patient underwent surgery f

Совпадение в полном тексте источника
… folds. … 2st: face 3nd: face | 1st: skin excision 2nd: facelift 3nd: facelift | Wong et al 12 7. | 2002 | 17 | Unknown | Unknown | Nasolabial fold, forehead, bilateral ear lobes | Nasolabial fold, forehead: fat grafting Bilateral ear lobes: reduction | Ben Jemaa et al 18 8. | 2004 | 27 | Female | Acquired | …

Важное значение акромагалоидных физических свойств для клинической практики.

Акромагали и гигантизм - это гормональные расстройства, которые возникают в результате гиперсекретирования хронического роста гормона. Псевдоним префикса используется для описания определенного клинического состояния без четко подтвержденной характеристики патофизиологического механизма и основных биохимических характеристик; псевдоакромегалы или акромигалоидизм соответствуют определению, приведенному выше. В данном случае мы попытаемся представить краткий обзор диагностической оценки акромигалоидной физической внешности при обсуждении two - случаи пациентов, которые имеют такие же клинические

Совпадение в полном тексте источника
… He had deep nasolabial folds, bulbous nose, blepharophimosis, drooping of eyelids, and enlarged frontal bones. The teeth were spread apart and he had a very deep voice. The most important symptom was macroglossia, which caused his reduced quality of life. …

Skin manifestations associated with systemic diseases - Part I.

The skin demonstrates what is happening in the body in many diseases, as it reflects some internal processes on the surface. In this sense, skin as an organ, goes beyond its protective and barrier functions, as it provides clues for the identification of some systemic diseases. The dermatologist then raises diagnostic hypotheses for conditions related to all systems and refers them to the appropriate specialty. With easy access to examination by trained eyes and biopsies, the skin can present specific or non specific alterations on histopathology. In the first case this combination establishes

Совпадение в полном тексте источника
… fold. … The malar erythema reaches the nasolabial fold as opposed to malar erythema in lupus erythematosus, which spares it. Pruritus: it can be intense and persistent, affecting the patient’s quality of life. …

A Clinical Genetics-Driven Dual Diagnosis of Prader-Willi Syndrome Due to Mosaic Maternal UPD(15) and NOTCH3-Related CADASIL.

Maternal uniparental disomy of chromosome 15 [UPD(15)mat] and imprinting defects account for about 30% of cases of Prader-Willi syndrome (PWS). Mosaic UPD(15)mat is rare and may escape routine testing. We describe a 45-year-old male patient in whom persistent clinical suspicion of PWS was not genetically confirmed by repeated methylation-based analyses. Clinical manifestations included neonatal hypotonia with low birth weight, early hyperphagia, severe obesity, short stature, growth hormone deficiency, type 2 diabetes mellitus, dyslipidemia, and MASLD/MASH with compensated cirrhosis. He presen

Cell Therapy: Types, Regulation, and Clinical Benefits.

Cell therapy practices date back to the 19th century and continue to expand on investigational and investment grounds. Cell therapy includes stem cell- and non-stem cell-based, unicellular and multicellular therapies, with different immunophenotypic profiles, isolation techniques, mechanisms of action, and regulatory levels. Following the steps of their predecessor cell therapies that have become established or commercialized, investigational and premarket approval-exempt cell therapies continue to provide patients with promising therapeutic benefits in different disease areas. In this review

Совпадение в полном тексте источника
… . | ( 24 ) LAVIV ® (azficel-T) | Autologous cellular product consisting of fibroblasts | Aesthetics of nasolabial fold wrinkles | Unknown | 2011 | Fibrocell Technologies, Inc. | ( 25 ) MACI ® (autologous cultured chondrocytes on porcine collagen membrane) | Cellular scaffold product consisting of autologous … fold wrinkles ( 25 ); chondrocyte-containing scaffold implants for treatment of knee cartilage defects ( 26 ); and cord blood-derived HSC/hematopoietic progenitor cell products for treatment of hematopoietic system disorders that are inherited, acquired, or result from myeloablative treatment ( 10 – …

Global Panoramic analysis of clinical research in cell therapy: clinical trial landscape, marketed products, and regulatory trends.

IntroductionCell therapy is a vital field in modern medicine. This review assesses its global clinical development landscape, approved products, and regional regulatory characteristics.MethodsA comprehensive search and analysis of global clinical trial databases (e.g., https://clinicaltrials.gov/ClinicalTrials.gov), regulatory agency announcements, and relevant literature up to October 2025 was conducted. Key data points regarding trial numbers, phases, therapy types, and approved products were extracted and analyzed descriptively by region.ResultsA cumulative total of 10,373 cell therapy clin

Совпадение в полном тексте источника
… A multicenter, double-blind, placebo-controlled trial of autologous fibroblast therapy for the treatment of nasolabial fold wrinkles. Dermatol. Surgery 38 (7 pt2), 1234–1243. 10.1111/j.1524-4725.2012.02349.x Song Y., Ying Z., Yang H., Guo Y., Li W., Zou D., et al. (2021). …

Storage diseases with hypertrophic cardiomyopathy phenotype.

Never judge a book by its cover, nor assume hypertrophic cardiomyopathy (HCM) as sarcomeric, as appearances can deceive. HCM phenocopies account for a 5-10% of the cases, mainly represented by storage diseases, flagged by the increasing prevalence of senile cardiac amyloid in developing countries. Multisystemic and heterogeneous presentation of these entities is a challenge for clinicians, and time delay in diagnosis is a major concern. Promising drugs and gene-specific tailored therapies are under development, therefore, more than ever, appropriate understanding of these conditions is mandato

Р

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: children and adolescents.

The Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Children and Adolescents was developed by dietitians, physicians, and pediatric hematologists from 10 Brazilian reference centers in hematopoietic stem cell transplantation. The aim was to emphasize the importance of nutritional status and body composition during treatment, as well as the main characteristics related to patient´s nutritional assessment. This consensus is intended to improve and standardize nutrition therapy during hematopoietic stem cell transplantation. The consensus was approved by the Brazilian