Результаты поиска

[Neuropsychological deficits in alcoholics: some implications for road safety].

AIM: There are various published studies showing that chronic alcoholics present cognitive deficit. In this conference we would like to review the most actual studies focusing on the neuropsychological alterations as consequences of the long and abusive alcohol intake. We also will analyse the involvement of these deficit in a complex task as driving. DEVELOPMENT: The long and abusive alcohol intake produces an affectation of the central nervous system. We could observe its consequences both in short and long term. Attention and memory deficit and a slowness of information processing are very

Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study.

Wernicke's encephalopathy (WE) is characterized by lesions in thalamus, hypothalamus (including mammillary nuclei), and inferior colliculi, results in serious disabilities, has an etiology of thiamine deficiency, is treatable with thiamine, and occurs most commonly with alcoholism. Despite decades of study, whether alcohol exposure exacerbates the neuropathology or retards its resolution remains controversial. To examine patterns of brain damage and recovery resulting from thiamine deprivation with and without alcohol exposure, we conducted in vivo magnetic resonance imaging (MRI) and magnetic

Dissecting medial temporal lobe from diencephalic sub-volumes: The amnesia dichotomy revisited.

Severe episodic memory deficits have historically been categorized as diencephalic amnesia, like in Korsakoff's Syndrome (KS), or as medial temporal lobe (MTL) amnesia, like in Alzheimer's Disease (AD). However, recent research has highlighted that both MTL and thalamus contribute to episodic memory. We aimed to challenge the traditional distinction by assessing whether subregional volume loss in the MTL and diencephalon reflects the distinct amnesia profiles traditionally associated with KS and AD. This cross-sectional observational study includes 203 subjects, comprising 81 healthy control p

Getting Pabrinex Right: A Multi-cycle Quality Improvement Study Reducing Waste in Thiamine Prescribing at a Scottish District General Hospital.

Background  Patients with alcohol use disorders (AUD) are at increased risk of Wernicke's encephalopathy (WE) due to thiamine deficiency. At our centre all admitted patients with AUD are assessed for signs, symptoms and risk factors for WE. Such patients are prescribed oral or intravenous (IV) thiamine replacement in accordance with local guidelines; choice of dose and route of administration is determined based on the clinical features present at presentation. Failure to appropriately treat patients with WE may lead to potentially avoidable progression to Korsakoff syndrome. However, unnecess…

Alcohol Withdrawal.

AUDIENCE: Emergency medicine residents and medical students on emergency medicine rotations. INTRODUCTION: Alcohol use disorder (AUD) is co … emia with concurrent administration of thiamine to prevent Wernicke's encephalopathy and subsequent Korsakoff syndrome, 5) appropriately treat acute alcohol withdrawal with intravenous (IV) hydration and benzodiazepines, phenobarbital, or alternative medications, and 6) understanding the need for the complex management of these patients, appropriately disposition th …

Clinical practice guidelines on addressing cognitive impairment in treatable dementias.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… The umbrella term ‘alcohol-related brain damage’ includes both ARD and the Wernicke–Korsakoff syndrome. Patients with ARD are mostly male, have their onset of symptoms younger compared to other dementias and lack social support. … levels EEG | EEG may show periodic slowing Porphyria | A combination of blood, urine or stool testing to measure porphyrin levels | Variable Vitamin B12 deficiency | Blood levels | Knuckle pigmentation Folate deficiency | Blood levels | Deficient levels Thiamine deficiency | Blood levels | Wernicke-Korsakoff …

Oncologic emergency in patients with skeletal metastasis of unknown primary.

AimPatients with skeletal metastasis from prediagnosed primary malignancy sometimes have concurrent oncologic emergency (OE) during the first visit. This study aims to investigate the types of OEs and treatment outcome in such patients.MethodsWe have experienced 359 patients with skeletal metastasis from unknown primary malignancy. Among them, 130 patients required immediate admission for OE treatment (OE group), 229 patients had no OE and did not required immediate admission (non-OE group).ResultsThe recognized types of OE were spinal cord compression in 60 patients, cancer pain in 30, hyperc

Совпадение в полном тексте источника
… Wernicke‐Korsakoff syndrome in patients with cancer: a systematic review. Lancet Oncol. 2016; 17: 142–8. 21. Onishi H, Kawanishi C, Onose M, et al Successful treatment of Wernicke encephalopathy in terminally ill cancer patients: report of 3 cases and review of the literature. …

Obesity Disease and Surgery.

Obesity is a medical disease that is increasing significantly nowadays. Worldwide obesity prevalence doubled since 1980. Obese patients are at great risk for complications with physical and psychological burdens, thus affecting their quality of life. Obesity is well known to have higher risk for cardiovascular diseases, diabetes mellitus, musculoskeletal diseases and shorter life expectancy. In addition, obesity has a great impact on surgical diseases, and elective surgeries in comparison to general population. There is higher risk for wound infection, longer operative time, poorer outcome, an

Novel Short PEG Chain-Substituted Porphyrins: Synthesis, Photochemistry, and In Vitro Photodynamic Activity against Cancer Cells.

This work presents the synthesis and characterization of metal-free, zinc (II), and cobalt (II) porphyrins substituted with short PEG chains. The synthesized compounds were characterized by UV-Vis, 1H and 13C NMR spectroscopy, and MALDI-TOF mass spectrometry. The origin of the absorption bands for tested compounds in the UV-Vis range was determined using a computational model based on the electron density functional theory (DFT) and its time-dependent variant (TD-DFT). The photosensitizing activity was evaluated by measuring the ability to generate singlet oxygen (ΦΔ), which reached values up

Алгоритмы машинного обучения для виртуального раннего обнаружения и выявления нейродегенеративных и нейрокогнитивных расстройств: систематический обзор.

Происхождение и аналоговые расстройства (например, болезнь Альцгеймера, болезнь Паркинсона) приводят к нейронной потере; нейрокогнитивные расстройства (например, бред, слабоумие) свидетельствуют о когнитивном упадке. Раннее обнаружение имеет решающее значение для эффективного управления. Машинное обучение помогает в более точном выявлении заболеваний, потенциально преобразуя медицинское обслуживание. В рамках этого всеобъемлющего систематического обзора обсуждается вопрос о том, каким образом машинное обучение (ML) может способствовать раннему выявлению этих расстройств, превосходя при этом тр

Резюме докладов 38th - ежегодное собрание общества общей внутренней медицины.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

The 46th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians Poster Session (P001-P706).

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Неделя ГЭЭ 2017 Презентации на плакате

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

UEG Week 2015 Poster Presentations

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.