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Feasibility and intra-operative accuracy of robotic-guided stacked S1AI and S2AI screw placement.

BACKGROUND: Pelvic fixation with S1 and S2 sacral alar-iliac screws (S1 & S2 AIs) in a stacked configuration can help to offset the exceedin … egenerative scoliosis = 26, idiopathic scoliosis = 8), followed in descending order by degenerative spondylolisthesis [10] and kyphosis [7]. Robotic guidance was successful in all 204 screws (4 screws per patient). There was no significant difference in the length of implants inserted on either side of the pelvis, however, the mean length of the S1 AIs (80 mm) was …

Transforaminal lumbar interbody fusion: the effect of various instrumentation techniques on the flexibility of the lumbar spine.

STUDY DESIGN: In vitro comparison of four reconstruction techniques following transforaminal lumbar interbody fusion in a human cadaveric mo … aining wide acceptance for the treatment of selected patients with segmental spinal instability and spondylolisthesis with associated degenerative changes. Each fusion technique may have different effects on the overall flexibility of the lumbar spine. The unilateral TLIF procedure with adjunctive pedicular fixation is one variation of an interbody fusion technique …

Precision measurement of disc height, vertebral height and sagittal plane displacement from lateral radiographic views of the lumbar spine.

OBJECTIVE.: To compile a database of disc height, vertebral height and sagittal plane displacement from lateral radiographic views of the lu … rs of age. Data from pathologically deformed vertebrae or discs, or from motion segments exhibiting spondylolisthesis or retrolisthesis were excluded by normal radiological inspection; data from spines showing normal, age-related degenerative changes were included. RESULTS.: The new protocols allow height and displacement of lumbar vertebrae as well as height of lu …

The effect of recombinant human bone morphogenetic protein-2 in single-level posterior lumbar interbody arthrodesis.

BACKGROUND: In this prospective, randomized controlled trial, our objective was to assess both the clinical and radiographic effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in patients treated with an instrumented single-level posterior lumbar interbody arthrodesis with polyetheretherketone cages. METHODS: Forty patients were randomized with a 1:1 ratio. Two patients who had a two-level arthrodesis (L4-L5 and L5-S1) were excluded. Patients completed the Oswestry Disability Index, the Short Form-36, and the visual analog scale preoperatively and postoperatively at three, six

Presumptive Prostate Cancer Presenting as Low Back Pain in the Chiropractic Office: Two Cases and Literature Review.

Prostate cancer is a common type of cancer in men and may metastasize to the spine and pelvis, causing back and/or radicular pain that appears to be musculoskeletal. This presents a diagnostic challenge and can be complicated by a lack of routine screening for prostate cancer. In two similar cases, elderly males (ages 78 and 82) with no known history of cancer and no previous prostate-specific antigen screening presented to a chiropractor with chronic, worsening radiating low back pain. In each case, a previous provider obtained radiographs and ascribed symptoms to a non-cancerous etiology (i.

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… Lumbar MRI was obtained the next day, which revealed a grade I L4/5 degenerative spondylolisthesis, and disc-osteophyte complex and bilateral facet hypertrophy at L4/5 and L5/S1 causing severe spinal canal stenosis and compression of the cauda equina. …

A scoping review of biopsychosocial risk factors and co-morbidities for common spinal disorders.

OBJECTIVE: The purpose of this review was to identify risk factors, prognostic factors, and comorbidities associated with common spinal disorders. METHODS: A scoping review of the literature of common spinal disorders was performed through September 2016. To identify search terms, we developed 3 terminology groups for case definitions: 1) spinal pain of unknown origin, 2) spinal syndromes, and 3) spinal pathology. We used a comprehensive strategy to search PubMed for meta-analyses and systematic reviews of case-control studies, cohort studies, and randomized controlled trials for risk and pro

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… , malignant, metastatic) • Intradural and epidural tumors • Meningeal carcinomatosis • Multiple myeloma | Metabolic | • Osteopenia | • Osteochondrosis (Scheurmann disease) • Osteitis fibrocystica • Ochronotic spondylosis • Paget disease | Congenital or developmental | • Scoliosis • Spina bifida • Spondylolisthesis … Disc space narrowing and spondylolisthesis were associated with low back pain in both community and occupation-based samples while spondylolisthesis was significantly more prevalent in the occupation population [pooled OR = 2.21 (95% CI, 1.44–3.39)] [ 97 ]. …

Oral Presentations

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Percutaneous Transforaminal Endoscopic Discectomy: Surgical Techniques, Indications, and Outcomes.

BACKGROUND: Percutaneous transforaminal endoscopic discectomy (PTED) is a minimally invasive technique for the treatment of symptomatic lumb … current LDH, paracentral LDH, extruded LDH, sequestration of the disc, significant obesity, isthmic spondylolisthesis, and severe canal stenosis11. Additionally, accessing the lower lumbar levels via a transforaminal approach may be difficult in patients with a high iliac crest. EXPECTED OUTCOMES: PTED is a safe procedure that has been shown to improve patient-rep …

Endoscopic foraminal decompression for failed back surgery syndrome under local anesthesia.

BACKGROUND: The most common causes of failed back surgery are residual or recurrent herniation, foraminal fibrosis and foraminal stenosis th … sc narrowing as a consequence of translaminar discectomy and progressive degenerative narrowing and spondylolisthesis (Figure 3) as a natural history of degenerative disc disease can lead to central and lateral stenosis. The MRI may underestimate the degree of stenosis from a bulging or a foraminal disc protrusion and residual lateral recess stenosis. Pain can be d …

Intelligence Architectures and Machine Learning Applications in Contemporary Spine Care.

The rapid evolution of artificial intelligence (AI) and machine learning (ML) technologies has initiated a paradigm shift in contemporary spine care. This narrative review synthesizes advances across imaging-based diagnostics, surgical planning, genomic risk stratification, and post-operative outcome prediction. We critically assess high-performing AI tools, such as convolutional neural networks for vertebral fracture detection, robotic guidance platforms like Mazor X and ExcelsiusGPS, and deep learning-based morphometric analysis systems. In parallel, we examine the emergence of ambient clini

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… This automated process allows for the one unified system to grade disk degeneration (e.g., Pfirrmann grades), endplate defects, bone marrow changes, foraminal stenosis, and spondylolisthesis [ 10 , 70 ]. … SpineNet and similar tools exhibit weaker performance in grading disk degeneration and quantifying spondylolisthesis for less common conditions; examples include sacral chordomas, which present atypical anatomy, histopathology, and metastatic patterns that are poorly represented in training sets [ 156 …

Development of Upright Computed Tomography With Area Detector for Whole-Body Scans: Phantom Study, Efficacy on Workflow, Effect of Gravity on Human Body, and Potential Clinical Impact.

OBJECTIVES: Multiple human systems are greatly affected by gravity, and many disease symptoms are altered by posture. However, the overall a … eal line. We also examined the usefulness of the upright CT in patients with functional diseases of spondylolisthesis, pelvic floor prolapse, and inguinal hernia. RESULTS: Noise characteristics, spatial resolution, and CT numbers on upright CT were comparable to those of supine CT. In the volunteer study, all volunteers answered yes regarding the stability of usin …

[Mid-term results of 360-degree lumbar spondylodesis with the use of a tantalum implant for disc replacement].

PURPOSE OF THE STUDY: The study presents the mid-term results in patients treated with circumferential, i.e., 360-degreee, fusion of the lum … ar screw fixation with decompression, if spinal stenosis existed, and reposition of the segment, if spondylolisthesis was present, and posterior spondylodesis by the open book method. No autogenous bone grafts were used because of the risk of donor-site pain and because one of the aims of the study was to test tantalum cage properties. Subsequently, ALIF and disc r …

[Early results and indications of Stand-alone oblique lateral interbody fusion in lumbar lesions].

OBJECTIVE: To summarize the early clinical results and safety of Stand-alone OLIF application of lumbar lesions, and explored its surgical indications. METHODS: Total of 92 cases of lumbar spine lesions treated with Stand-alone OLIF at two medical centers from October 2014 to December 2018 were retrospectively analyzed, including 30 males and 62 females with an average age of (61.20±12.94) years old ranged from 32 to 83 years old. There were 20 cases of lumbar spinal stenosis, 15 cases of lumbar disc degeneration, 11 cases of lumbar degenerative spondylolisthesis, 6 cases of discogenic low ba…

Application of Gelatin Sponge Impregnated with a Mixture of 3 Drugs to Intraoperative Nerve Root Block Combined with Robot-Assisted Minimally Invasive Transforaminal Lumbar Interbody Fusion Surgery in the Treatment of Adult Degenerative Scoliosis: A Clinical Observation Including 96 Patients.

OBJECTIVE: Application of nerve root block is mainly for diagnosis with less application in intraoperative treatment. The aim of this study was to observe clinical and imaging outcomes of application of gelatin sponge impregnated with a mixture of 3 drugs to intraoperative nerve root block combined with robot-assisted minimally invasive transforaminal lumbar interbody fusion surgery in to treat adult degenerative lumbar scoliosis. METHODS: From January 2012 to November 2014, 108 patients with adult degenerative lumbar scoliosis were treated with robot-assisted minimally invasive transforamina

Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF): A Video Technique Guide.

BACKGROUND: Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) has been established as an excellent alternative to the trad … -TLIF include most degenerative pathology of the lumbar spine, including disc herniation, low-grade spondylolisthesis, and spinal and foraminal stenosis7. However, MI-TLIF allows for less robust correction of deformity than other minimally invasive approaches; therefore, MI-TLIF may not be as effective in cases of substantial spinal deformity or high-grade spondylo …

Safety and Efficacy of Anterior Cervical Corpectomy and Reconstruction With Expandable Cages for Treatment of Cervical Myelopathy-Focusing on Stand-Alone Cages: A Systematic Review and Meta-Analysis.

Study DesignSystematic review and Meta-analysis.ObjectivesThis study aims to evaluate the efficacy, postoperative outcomes, and potential complications of using expandable cages in cervical spine surgery.MethodsA comprehensive search was performed across Medline, Scopus, Web of Science, Cochrane, and Embase up to May 22, 2023. Meta-analyses and subgrouping analyses were performed using "OpenMetaAnalyst" and R software to analyze efficacy outcomes and complications. The assessment of heterogeneity utilized the i2 and chi-squared tests, applying the random effect model.ResultsThirty studies were

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… ADF OR “Anterior cervical decompression and fusion with corpectomy” OR ACDF OR “Anterior cervical vertebrectomy” OR “Anterior cervical osteotomy and corpectomy” OR “Anterior cervical resection and fusion” OR ACRF OR “Anterior cervical spine surgery with corpectomy” AND “Myelopathy OR Spondylosis OR Spondylolisthesis … Spondylolisthesis in 2 cases 7. Epidural bleeding in 1 case | 1. Cervical corpectomy and reconstruction with expandable cervical cage plus ventral plating in 16 patients 2. …

Clinical neurology.

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Characterization of degenerative human facet joints and facet joint capsular tissues.

OBJECTIVE: Lumbar facet joint degeneration (FJD) may be an important cause of low back pain (LBP) and sciatica. The goal of this study was to characterize cellular alterations of inflammatory factor expression and neovascularization in human degenerative facet joint capsular (FJC) tissue. These alterations in FJC tissues in pain stimulation were also assessed. DESIGN: FJs were obtained from consented patients undergoing spinal reconstruction surgery and cadaveric donors with no history of back pain. Histological analyses of the FJs were performed. Cytokine antibody array and quantitative real

Orthopaedic Oncology in Contemporary Practice: A Comprehensive Review of Primary Bone Tumours, Metastatic Pathways, and Evolving Surgical Techniques.

Orthopaedic oncology encompasses the diagnosis and management of primary bone sarcomas and metastatic skeletal disease, requiring integration of oncologic principles with complex musculoskeletal reconstruction. Advances in molecular classification, cross-sectional imaging, systemic therapy, and surgical technology have substantially transformed contemporary clinical practice. This comprehensive review synthesises current evidence across epidemiology, tumour biology, diagnostic strategies, staging systems, multidisciplinary management, reconstructive techniques, complication profiles, and survi

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… Spondylolysis and isthmic spondylolisthesis: a guide to diagnosis and management. Mohile NV, Kuczmarski AS, Lee D, Warburton C, Rakoczy K, Butler AJ. J Am Board Fam Med. 2022;35:1204–1216. doi: 10.3122/jabfm.2022.220130R1. …

The Role of Minimal Access Surgery in the Treatment of Spinal Metastatic Tumors.

Study designLiterature review.ObjectiveTo provide an overview of the recent advances in minimal access surgery (MAS) for spinal metastases.MethodsLiterature review.ResultsExperience gained from MAS in the trauma, degenerative and deformity settings has paved the road for MAS techniques for spinal cancer. Current MAS techniques for the treatment of spinal metastases include percutaneous instrumentation, mini-open approaches for decompression and tumor resection with or without tubular/expandable retractors and thoracoscopy/endoscopy. Cancer care requires a multidisciplinary effort and adherence

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… Minimally invasive versus open fusion for Grade I degenerative lumbar spondylolisthesis: analysis of the Quality Outcomes Database . Neurosurg Focus . 2017 ; 43 : E11 doi:10.3171/2017.5.FOCUS17188 10.3171/2017.5.FOCUS17188 28760035 61 McGirt MJ Parker SL Mummaneni P , et al. …