Irish medical journal · 2025
Clival metastasis presenting with oculomotor nerve palsy in a patient with a prior history of breast cancer.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Visser E, Elmusharaf K, Ryan A, O'Connor M
Аннотация
PRESENTATION: A 77-year-old female patient presented with a short history of left sided ptosis, temporal headache, retro-orbital pain and diplopia having had a history of Stage IIA (T1mfN1) right breast cancer two years previously.
DIAGNOSIS: CT-brain imaging documented an enhancing clival lesion and no other sites of disease. Histopathology via endoscopic transsphenoidal craniotomy debulking confirmed metastatic breast cancer.
TREATMENT: Transsphenoidal craniotomy debulking resulted in symptomatic relief and resolved the ptosis and diplopia. She received stereotactic radiosurgery (SRS). She was commenced on bisphosphonate and systemic chemotherapy.
DISCUSSION: Clival metastases have been reported in association with a myriad of cancers; however, there are limited cases of solitary clival metastasis in the literature, none of which have presented with an oculomotor nerve palsy.
DIAGNOSIS: CT-brain imaging documented an enhancing clival lesion and no other sites of disease. Histopathology via endoscopic transsphenoidal craniotomy debulking confirmed metastatic breast cancer.
TREATMENT: Transsphenoidal craniotomy debulking resulted in symptomatic relief and resolved the ptosis and diplopia. She received stereotactic radiosurgery (SRS). She was commenced on bisphosphonate and systemic chemotherapy.
DISCUSSION: Clival metastases have been reported in association with a myriad of cancers; however, there are limited cases of solitary clival metastasis in the literature, none of which have presented with an oculomotor nerve palsy.