Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
Perioperative risk factors predicting CSF leak and retethering following tethered cord release for complex spinal lipomas.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chesney Kelsi M, McAbee Joseph H, Balu Alan, Liu Jiaqi, Mehta Aadit, Stirrat Thomas, Kazemi Foad, Daniels Katherine, Oluigbo Chima, Myseros John S, Keating Robert F
Аннотация
PURPOSE: Tethered cord release (TCR) is typically well tolerated in children, but cerebrospinal fluid (CSF) leaks can occur postoperatively, with rates as high as 33%. The aim of this study was to determine perioperative risk factors associated with CSF leaks and retethering following TCR for complex spinal lipomas to predict higher risk patients.
METHODS: A retrospective review was performed for complex spinal lipoma patients who underwent TCR at Children's National Hospital from 1996 to 2023. Demographics, operative techniques, postoperative management, and outcomes were analyzed.
RESULTS: A total of 131 patients with complex spinal lipomas underwent 168 operations for TCR. Fifteen patients experienced a postoperative CSF leak (8.9%). Patients with an increased leak risk were significantly older (11.2 vs. 1.2 years), presented symptomatically, and had a history of prior detethering. A significantly higher number of leaks was observed after dural closure with Nurolon sutures compared to Prolene. Lying flat postoperatively for fewer days did not influence leak rates. Leak patients experience significantly longer hospital stays, higher wound infection rates, and a higher likelihood of retethering. Patients with preoperative symptoms, prior TCR, and transitional lipomas had a lower PFS and were more likely to retether after TCR.
CONCLUSION: Children undergoing TCR for complex spinal lipomas may be at higher risk of CSF leak if they are older, underwent prior detethering, or presented symptomatically. Nurolon sutures may increase leak risk compared with Prolene. Interestingly, lying flat for fewer days postoperatively did not increase leak risk, suggesting patients may be able to safely mobilize sooner.
METHODS: A retrospective review was performed for complex spinal lipoma patients who underwent TCR at Children's National Hospital from 1996 to 2023. Demographics, operative techniques, postoperative management, and outcomes were analyzed.
RESULTS: A total of 131 patients with complex spinal lipomas underwent 168 operations for TCR. Fifteen patients experienced a postoperative CSF leak (8.9%). Patients with an increased leak risk were significantly older (11.2 vs. 1.2 years), presented symptomatically, and had a history of prior detethering. A significantly higher number of leaks was observed after dural closure with Nurolon sutures compared to Prolene. Lying flat postoperatively for fewer days did not influence leak rates. Leak patients experience significantly longer hospital stays, higher wound infection rates, and a higher likelihood of retethering. Patients with preoperative symptoms, prior TCR, and transitional lipomas had a lower PFS and were more likely to retether after TCR.
CONCLUSION: Children undergoing TCR for complex spinal lipomas may be at higher risk of CSF leak if they are older, underwent prior detethering, or presented symptomatically. Nurolon sutures may increase leak risk compared with Prolene. Interestingly, lying flat for fewer days postoperatively did not increase leak risk, suggesting patients may be able to safely mobilize sooner.