Cornea · 2009
Penetrating keratoplasty with small-diameter and glycerin-cryopreserved grafts for eccentric corneal perforations.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
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Shi Weiyun, Liu Mingna, Gao Hua, Li Suxia, Wang Ting, Xie Lixin
Аннотация
PURPOSE: To report the outcome of penetrating keratoplasty with small-diameter and glycerin-cryopreserved grafts for eccentric corneal perforation.
METHODS: In this retrospective consecutive case series, 15 eyes of 15 patients with eccentric corneal perforations underwent small-diameter penetrating keratoplasties with glycerin-cryopreserved grafts. The corneal grafts used in this study were 2.5-4.5 mm in size and preserved at -20 degrees C in pure glycerin for 6 months to 5 years. The donors were secured with 6-8 sutures that spared the visual axis. The follow-up ranged from 7 to 36 months. Clarity of the grafts was observed, and changes in visual acuity and keratometric astigmatism were analyzed.
RESULTS: : Global integrity was achieved in all eyes. All grafts remained clear at the end of the follow-up time. No immune rejection was detected. No complicated cataract or secondary glaucoma was developed. The uncorrected visual acuity improved from preoperative 20/2000 approximately 20/60 to postoperative 20/40 approximately 20/20, and the best-corrected visual acuity after surgery was 20/30 or better. The mean value of keratometric astigmatism was 2.47 +/- 0.78 diopters postoperatively.
CONCLUSIONS: Small-diameter penetrating keratoplasty seems to be effective in treating various eccentric corneal perforations. Glycerin-cryopreserved donors may be a suitable alternative to fresh material for this technique, which solves the problem of shortage in supplying corneas and can be used in an emergency.
METHODS: In this retrospective consecutive case series, 15 eyes of 15 patients with eccentric corneal perforations underwent small-diameter penetrating keratoplasties with glycerin-cryopreserved grafts. The corneal grafts used in this study were 2.5-4.5 mm in size and preserved at -20 degrees C in pure glycerin for 6 months to 5 years. The donors were secured with 6-8 sutures that spared the visual axis. The follow-up ranged from 7 to 36 months. Clarity of the grafts was observed, and changes in visual acuity and keratometric astigmatism were analyzed.
RESULTS: : Global integrity was achieved in all eyes. All grafts remained clear at the end of the follow-up time. No immune rejection was detected. No complicated cataract or secondary glaucoma was developed. The uncorrected visual acuity improved from preoperative 20/2000 approximately 20/60 to postoperative 20/40 approximately 20/20, and the best-corrected visual acuity after surgery was 20/30 or better. The mean value of keratometric astigmatism was 2.47 +/- 0.78 diopters postoperatively.
CONCLUSIONS: Small-diameter penetrating keratoplasty seems to be effective in treating various eccentric corneal perforations. Glycerin-cryopreserved donors may be a suitable alternative to fresh material for this technique, which solves the problem of shortage in supplying corneas and can be used in an emergency.
Предметные рубрики MeSH
AdolescentAdultAstigmatismChildCorneaCorneal DiseasesCorneal InjuriesCorneal UlcerCryopreservationCryoprotective AgentsEye Infections, BacterialEye Infections, FungalFemaleFollow-Up StudiesGlycerolGraft SurvivalHumansKeratitisKeratitis, HerpeticKeratoplasty, PenetratingMaleMiddle AgedPostoperative PeriodRetrospective StudiesVisual AcuityWounds, PenetratingYoung Adult