Clinical and experimental dermatology · 2025
Pyogenic granuloma-like Spitz naevus in paediatric patients: a case series.
СтатьяНазвание и аннотация: Перевод в очереди
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Olshinka Asaf, Harris Rimon Gaia, Lapidoth Moshe, Mimouni Daniel, Ingber Israel, Khalil Mohammad, Didkovsky Elena, Levi Assi, Noyman Yehonatan
Аннотация
BACKGROUND: Pyogenic granuloma is a benign vascular lesion. The differential diagnosis encompasses both malignant and benign conditions. While several modalities are available for its management, only surgical options enable a histopathological diagnosis, which is crucial to rule out clinical mimickers.
OBJECTIVES: To examine paediatric patients with pyogenicgranuloma-like Spitz naevus and emphasize the importance of tissue sampling for diagnostic accuracy and optimal care.
METHODS: A retrospective single-centre study of paediatric patients with lesions clinically diagnosed as pyogenic granuloma ultimately diagnosed as Spitz naevus following a histopathological evaluation between January 2018 and December 2023.
RESULTS: Of 84 paediatric patients with clinically suspected pyogenic granuloma who underwent biopsy, 6 (7.1%) were diagnosed with Spitz naevus. All lesions had involved surgical margins requiring re-excision, which achieved clear margins with no recurrences during an average follow-up of 27.5 months. The mean age of the patients at onset was 2 years 4 months. Lesions were evenly distributed between the face and extremities.
CONCLUSIONS: The broad differential diagnosis of pyogenic granuloma highlights the risk of misdiagnosis when solely relying on a clinical diagnosis. Although nonsurgical treatments are convenient, the high clinicopathological discrepancy rate further underscores the need for histopathological confirmation.
OBJECTIVES: To examine paediatric patients with pyogenicgranuloma-like Spitz naevus and emphasize the importance of tissue sampling for diagnostic accuracy and optimal care.
METHODS: A retrospective single-centre study of paediatric patients with lesions clinically diagnosed as pyogenic granuloma ultimately diagnosed as Spitz naevus following a histopathological evaluation between January 2018 and December 2023.
RESULTS: Of 84 paediatric patients with clinically suspected pyogenic granuloma who underwent biopsy, 6 (7.1%) were diagnosed with Spitz naevus. All lesions had involved surgical margins requiring re-excision, which achieved clear margins with no recurrences during an average follow-up of 27.5 months. The mean age of the patients at onset was 2 years 4 months. Lesions were evenly distributed between the face and extremities.
CONCLUSIONS: The broad differential diagnosis of pyogenic granuloma highlights the risk of misdiagnosis when solely relying on a clinical diagnosis. Although nonsurgical treatments are convenient, the high clinicopathological discrepancy rate further underscores the need for histopathological confirmation.