Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2007
Nonfunctioning endocrine tumor arising from intracranial ectopic pancreas associated with congenital brain malformation.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tsugu Hitoshi, Oshiro Shinya, Kawaguchi Hiroshi, Fukushima Takeo, Nabeshima Kazuki, Matsumoto Shinji, Nomura Yuko, Yasumoto Sawa, Takano Koichi, Utsunomiya Hidetsuna
Аннотация
CASE REPORT: We report a case of a nonfunctioning pancreatic endocrine tumor arising from intracranial ectopic pancreatic tissue.
HISTORY: An 11-year-old girl was admitted to our hospital with a brain tumor. Hydrocephalus and brain malformation were apparent at birth. We first identified a mass-like lesion in the child's brain at age 4 months. We monitored the lesion yearly by magnetic resonance imaging (MRI) until she reached age 11 years. Gadolinium-enhanced MRI showed the lesion to be a tumor, which was resected.
PATHOLOGY: Examination of surgical specimens revealed a mature pancreatic tissue. We also identified monotonous neoplastic cells with round nuclei and positive immunoreactivity for synaptophysin, chromogranin A, and neurospecific enolase. However, these cells were negative for pancreatic endocrine markers. We diagnosed nonfunctioning pancreatic endocrine tumor arising from intracranial ectopic pancreatic tissue.
CONCLUSION: Migrating pancreatic elements may have induced brain malformation during embryonic development and subsequently become malignant.
HISTORY: An 11-year-old girl was admitted to our hospital with a brain tumor. Hydrocephalus and brain malformation were apparent at birth. We first identified a mass-like lesion in the child's brain at age 4 months. We monitored the lesion yearly by magnetic resonance imaging (MRI) until she reached age 11 years. Gadolinium-enhanced MRI showed the lesion to be a tumor, which was resected.
PATHOLOGY: Examination of surgical specimens revealed a mature pancreatic tissue. We also identified monotonous neoplastic cells with round nuclei and positive immunoreactivity for synaptophysin, chromogranin A, and neurospecific enolase. However, these cells were negative for pancreatic endocrine markers. We diagnosed nonfunctioning pancreatic endocrine tumor arising from intracranial ectopic pancreatic tissue.
CONCLUSION: Migrating pancreatic elements may have induced brain malformation during embryonic development and subsequently become malignant.