The Swedish Society of Paediatric Infectious Diseases' 2025 Recommendations for the Initial Management of Suspected Paediatric Sepsis With or Without Shock.

The Swedish Society of Paediatric Infectious Diseases worked with paediatric societies for emergency medicine, anaesthesia, and intensive care to produce the 2025 recommendations for the initial management of suspected sepsis. They cover 28 days of corrected age to 18 years, but exclude immunodeficiency, immunosuppression, and suspected meningitis. Suspicion of sepsis and sepsis-associated shock is based on clinical findings, vital parameters, and lactate levels, if available. Treatment should be initiated within 1 h of suspicion for sepsis with shock and 3 h for sepsis without shock. It includes intravenous fluids and antibiotics. Vasoactive medication, corticosteroids, and immunomodulatory therapies are added if needed.