Pediatric surgery international · 2025
Sclerotherapy as first-line treatment of rectal prolapse in children, including those with anorectal malformations.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Dariel Anne, El Khoury Eliane, Charbonnier Matthieu, Pinol Jessica, Rouy Mathieu, Faure Alice, Panait Nicoleta, Borrione Claude
Аннотация
PURPOSE: To evaluate the efficacy of injection sclerotherapy in the management of reducible rectal prolapse (RP) in children.
METHODS: Children with reducible RP who underwent sclerotherapy with Kinurea-H® (quinine dihydrochloride/urea) were retrospectively included, and divided into 2 groups, functional RP (FRP) or organic RP (ORP).
RESULTS: Thirty-two patients were included, 18 FRP and 14 ORP (7 anorectal malformation (ARM), 2 anorexia nervosa, 1 Hirschsprung disease, 2 spinal dysraphism, 1 Ehlers-Danlos, 1 short bowel syndrome) with a median age of 4 years. After one injection, the success rate was higher in FRP (78%) than in ORP (21%) (p = 0.0009). After 2-4 injections, success rate was 94% in FRP and 93% in ORP, with a minimal mucosal resection of the fixed portion (less than 5 mm, limited to the ano-cutaneous junction) in 4/7 ARM. Repeated injections were performed at same site in all ORP without ARM, and in only 43% of ORP with ARM. Recurrence of reducible RP after the first injection at one site was associated with ORP (p = 0.03), particularly in ORP without ARM (p = 0.06).
CONCLUSION: Sclerotherapy for reducible RP is efficient after failure of conservative management in FRP and success rate after repeated injections is encouraging in ORP, particularly in ARM.
METHODS: Children with reducible RP who underwent sclerotherapy with Kinurea-H® (quinine dihydrochloride/urea) were retrospectively included, and divided into 2 groups, functional RP (FRP) or organic RP (ORP).
RESULTS: Thirty-two patients were included, 18 FRP and 14 ORP (7 anorectal malformation (ARM), 2 anorexia nervosa, 1 Hirschsprung disease, 2 spinal dysraphism, 1 Ehlers-Danlos, 1 short bowel syndrome) with a median age of 4 years. After one injection, the success rate was higher in FRP (78%) than in ORP (21%) (p = 0.0009). After 2-4 injections, success rate was 94% in FRP and 93% in ORP, with a minimal mucosal resection of the fixed portion (less than 5 mm, limited to the ano-cutaneous junction) in 4/7 ARM. Repeated injections were performed at same site in all ORP without ARM, and in only 43% of ORP with ARM. Recurrence of reducible RP after the first injection at one site was associated with ORP (p = 0.03), particularly in ORP without ARM (p = 0.06).
CONCLUSION: Sclerotherapy for reducible RP is efficient after failure of conservative management in FRP and success rate after repeated injections is encouraging in ORP, particularly in ARM.