Clinical neurology and neurosurgery · 2025
Predicting dementia severity changes after shunt surgery for idiopathic normal-pressure hydrocephalus: Role of the tap test and cognitive assessments.
СтатьяНаблюдательное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Koizumi Fuyuki, Kanemoto Hideki, Suehiro Takashi, Sato Shunsuke, Satake Yuto, Taomoto Daiki, Yoshiyama Kenji, Hosomi Koichi, Kishima Haruhiko, Ikeda Manabu
Аннотация
OBJECTIVE: To determine the most appropriate assessment scale and timing of the tap test for predicting improvements in dementia severity after shunt surgery in patients with idiopathic normal-pressure hydrocephalus (iNPH).
METHODS: Data were extracted from an observational study that followed patients with iNPH as follows: Patients diagnosed with possible iNPH and scheduled for a tap test were enrolled. Patients diagnosed with probable iNPH by the tap test underwent shunting and followed up for 3 months after shunting. Patients with missing data in the tap test assessment items (gait speed: 3 consecutive days before tapping and 3 consecutive days after tapping; cognition: before tapping, 1 day after tapping and 1 week after tapping; and urinary dysfunction: before tapping and 1 week after tapping) or in the Clinical Dementia Rating (CDR) assessed before tapping and 3 months after shunting were excluded from this study.
RESULTS: 54 patients were included in the analysis. The change in CDR-Sum of Boxes (CDR-SoB) score after shunt surgery was significantly correlated with the change in Mini-Mental State Examination (MMSE) score (β = -0.417, p < 0.001) and Frontal Assessment Battery (FAB) score (β = -0.379, p = 0.002) 3 months after shunt surgery after adjusting for age and sex. The change in MMSE score after shunt surgery was correlated with the change in MMSE score 1 day after tapping (β = 0.411, p = 0.001), the change in the minimum Timed Up and Go test score across repeated tests after tapping (β = -0.376, p = 0.004) and attention/concentration in Wechsler Memory Scale-Revised 1 day after tapping (β = -0.289, p = 0.024). The change in FAB score after shunt surgery was correlated with the change in the maximum FAB score across repeated tests after tapping (β = 0.523, p < 0.001).
CONCLUSION: Combining MMSE and FAB assessments during the tap test may yield more useful information in assessing cognitive impairment than using either MMSE or FAB alone.
METHODS: Data were extracted from an observational study that followed patients with iNPH as follows: Patients diagnosed with possible iNPH and scheduled for a tap test were enrolled. Patients diagnosed with probable iNPH by the tap test underwent shunting and followed up for 3 months after shunting. Patients with missing data in the tap test assessment items (gait speed: 3 consecutive days before tapping and 3 consecutive days after tapping; cognition: before tapping, 1 day after tapping and 1 week after tapping; and urinary dysfunction: before tapping and 1 week after tapping) or in the Clinical Dementia Rating (CDR) assessed before tapping and 3 months after shunting were excluded from this study.
RESULTS: 54 patients were included in the analysis. The change in CDR-Sum of Boxes (CDR-SoB) score after shunt surgery was significantly correlated with the change in Mini-Mental State Examination (MMSE) score (β = -0.417, p < 0.001) and Frontal Assessment Battery (FAB) score (β = -0.379, p = 0.002) 3 months after shunt surgery after adjusting for age and sex. The change in MMSE score after shunt surgery was correlated with the change in MMSE score 1 day after tapping (β = 0.411, p = 0.001), the change in the minimum Timed Up and Go test score across repeated tests after tapping (β = -0.376, p = 0.004) and attention/concentration in Wechsler Memory Scale-Revised 1 day after tapping (β = -0.289, p = 0.024). The change in FAB score after shunt surgery was correlated with the change in the maximum FAB score across repeated tests after tapping (β = 0.523, p < 0.001).
CONCLUSION: Combining MMSE and FAB assessments during the tap test may yield more useful information in assessing cognitive impairment than using either MMSE or FAB alone.