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Journal of the American Academy of Dermatology · 2007

Contact dermatitis of the hands: cross-sectional analyses of North American Contact Dermatitis Group Data, 1994-2004.

СтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Warshaw Erin M, Ahmed Rehana L, Belsito Donald V, DeLeo Vincent A, Fowler Joseph F, Maibach Howard I, Marks James G, Toby Mathias C G, Pratt Melanie D, Rietschel Robert L, Sasseville Denis, Storrs Frances J, Taylor James S, Zug Kathryn A, North American Contact Dermatitis Group

Аннотация

BACKGROUND: Hand dermatitis, including irritant and allergic contact dermatitis (ACD), is common.

OBJECTIVE: To evaluate allergens, relevant irritants, sources and occupations associated with hand contact dermatitis using North American Contact Dermatitis Group (NACDG) data.

METHODS: A cross-sectional analysis of 22,025 patients patch tested between 1994 and 2004.

RESULTS: Hand involvement was found in 6953 patients; 959 had ACD as the only diagnosis. In these 959 patients, the 12 most frequent relevant allergens were quaternium-15 (16.5%), formaldehyde (13.0%), nickel sulfate (12.2%), fragrance mix (11.3%), thiuram mix (10.2%), balsam of Peru (9.6%), carba mix (7.8%), neomycin sulfate (7.7%), bacitracin (7.4%), methyldibromoglutaronitrile/phenoxyethanol 2.0% (7.4%), cobalt chloride (6.5%), and methyldibromoglutaronitrile/phenoxyethanol 2.5% (6.3%). Rubber allergens were most commonly associated with occupation. One third of patients with hand ACD had identifiable relevant irritants.

LIMITATIONS: Cross-sectional analyses prevent evaluation of causal associations.

CONCLUSION: In NACDG patients with hand ACD, the most common allergens included preservatives, metals, fragrances, topical antibiotics, and rubber additives.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты