Multiple cases of sensitization to an antiseptic containing chlorhexidine digluconate/benzalkonium chloride/benzyl alcohol with different profiles of sensitization in adults and children.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Beaumont Charlotte, Darrigade Anne-Sophie, Barbaud Annick, Collet Evelyne, Raison-Peyron Nadia, Bourrain Jean-Luc, Assier Haudrey, Giordano-Labadie Françoise, Bara-Passot Corina, Milpied Brigitte, Tétart Florence, Armingaud Pierre, Castelain Florence, Benkalfate Lamia, Boulard Claire, Delaunay Juliette, Mathelier-Fusade Pascale, Pecquet Catherine, Pralong Pauline, Vital-Durand Dominique, Genillier Foin Nathalie, Lefèvre Marine-Alexia, Hacard Florence, Nosbaum Audrey, Pasteur Justine, Valois Aude, Vigan Martine, Ferrier le Bouëdec Marie-Christine, REVIDAL-GERDA Network
Аннотация
OBJECTIVES: To evaluate the clinical and sensitization profiles of patients diagnosed with ACD to CBB.
METHODS: We performed a retrospective study of patients with contact dermatitis to CBB and positive tests to CBB and/or at least one of its components. All patients had to be tested with all components of CBB.
RESULTS: A total of 102 patients (71 adults and 31 children) were included. The lesions were extensive in 63% of patients and 55% had delayed time to diagnosis. CBB patch tests were positive in 93.8% of cases. The allergen was identified in 97% of patients, mainly benzyl alcohol in adults (81.7%) and chlorhexidine digluconate in children (54.8%). About 32.4% of the patients were sensitized to several components.
CONCLUSION: CBB is a cause of ACD at all ages. The components of the antiseptic should be tested. The sensitization profile seems to be different between adults and children.