Stomatologija · 2025
Prevalence of infectious diseases and disorders of dermal apparatus in relation to head and neck region pertaining to adult and paediatric population - An original research.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Karthikeyini Harepriya Meganathan, Shunmugavelu Karthik, Dhinakaran Evangeline Cynthia
Аннотация
BACKGROUND AND OBJECTIVE: Immunologically mediated mucocutaneous diseases frequently manifest initially in the oral cavity and often exhibit overlapping clinical features. This overlap complicates early clinical diagnosis and may delay appropriate management. The present study aimed to assess the prevalence and clinicopathological characteristics of oral lichen planus, oral pemphigus and oral pemphigoid in a large retrospective cohort.
MATERIAL AND METHODS: A retrospective analysis of 6300 biopsy records archived over a 21-year period was performed. Cases diagnosed histopathologically as oral lichen planus, oral pemphigus and oral pemphigoid were included. Demographic details and clinical features were retrieved from records. Hematoxylin and eosin stained sections were re-evaluated using current diagnostic criteria. Descriptive statistical analysis was carried out using SPSS version 21.
RESULTS: Out of 6300 cases, 105 (1.66%) were immunologically mediated oral diseases. Oral lichen planus constituted 86 cases (1.36%), oral pemphigoid 15 cases (0.23%) and oral pemphigus 4 cases (0.06%). Characteristic clinicopathological features were observed for each entity, with oral lichen planus being the most prevalent.
CONCLUSIONS: Immunologically mediated oral diseases represented a small proportion of oral biopsy specimens. Overlapping clinical features necessitate careful clinicopathological correlation to ensure accurate diagnosis. Histopathological examination remains essential for definitive diagnosis and appropriate management.
MATERIAL AND METHODS: A retrospective analysis of 6300 biopsy records archived over a 21-year period was performed. Cases diagnosed histopathologically as oral lichen planus, oral pemphigus and oral pemphigoid were included. Demographic details and clinical features were retrieved from records. Hematoxylin and eosin stained sections were re-evaluated using current diagnostic criteria. Descriptive statistical analysis was carried out using SPSS version 21.
RESULTS: Out of 6300 cases, 105 (1.66%) were immunologically mediated oral diseases. Oral lichen planus constituted 86 cases (1.36%), oral pemphigoid 15 cases (0.23%) and oral pemphigus 4 cases (0.06%). Characteristic clinicopathological features were observed for each entity, with oral lichen planus being the most prevalent.
CONCLUSIONS: Immunologically mediated oral diseases represented a small proportion of oral biopsy specimens. Overlapping clinical features necessitate careful clinicopathological correlation to ensure accurate diagnosis. Histopathological examination remains essential for definitive diagnosis and appropriate management.