Shape Analysis of the Corpus Callosum in Pediatric Hydrocephalus: A Comparison Between Cases with and without Shunt Revision Surgery.

AIM: To investigate corpus callosum shape differences in pediatric hydrocephalus patients with and without shunt revisions.

MATERIAL AND

METHODS

Midsagittal magnetic resonance imaging studies from 45 cases (25 with and 20 without shunt revision surgeries) that underwent ventriculoperitoneal shunt surgery between 2016 and 2025 were retrospectively analyzed. Corpus callosum shape deformations were evaluated using thin plate spline (TPS) analysis. Landmark-based geometric morphometric methods were applied, and growth curve modeling was used to assess the relationship between centroid size and the number of shunt revisions.

RESULTS

TPS analysis revealed that patients with multiple shunt revisions exhibited the most prominent corpus callosum deformations in the posterior region. Atrophy was detected mainly in the splenium region.

CONCLUSION

This study identified changes in the corpus callosum of pediatric hydrocephalus patients with multiple shunt revisions compared to those without shunt revisions. These findings may help characterize the clinical features of cases with multiple shunt revisions.