Stroke · 2013
Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Kim Jinkwon, Song Tae-Jin, Song Dongbeom, Lee Hye Sun, Nam Chung Mo, Nam Hyo Suk, Kim Young Dae, Heo Ji Hoe
Аннотация
BACKGROUND AND PURPOSE: We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke.
METHODS: We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI.
RESULTS: NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes.
CONCLUSIONS: The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.
METHODS: We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI.
RESULTS: NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes.
CONCLUSIONS: The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.