Emerging infectious diseases · 2019
Sporotrichosis in the Highlands of Madagascar, 2013-20171.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Rasamoelina Tahinamandranto, Maubon Danièle, Raharolahy Onivola, Razanakoto Harinjara, Rakotozandrindrainy Njary, Rakotomalala Fetra Angelot, Bailly Sébastien, Sendrasoa Fandresena, Ranaivo Irina, Andrianarison Malalaniaina, Rakotonirina Benja, Andriantsimahavandy Abel, Rabenja Fahafahantsoa Rapelanoro, Andrianarivelo Mala Rakoto, Ramarozatovo Lala Soavina, Cornet Muriel
Аннотация
Sporotrichosis is a saprozoonotic fungal infection found mostly in tropical and subtropical areas. Few case reports in Madagascar have been published. To document sporotrichosis epidemiology in Madagascar, we conducted a cross-sectional study. During March 2013-June 2017, we recruited from select hospitals in Madagascar patients with chronic cutaneous lesions suggestive of dermatomycosis. Sporotrichosis was diagnosed for 63 (42.5%) of 148 patients. All but 1 patient came from the central highlands, where the prevalence was 0.21 cases/100,000 inhabitants. Frequency was high (64.7%) among patients <18 years of age. Sporotrichosis was diagnosed for 73.8% of patients with arm lesions, 32.3% with leg lesions, and 15.4% with lesions at other sites. Molecular identification identified 53 Sporothrix schenckii isolates. Among the 32 patients who were followed up, response to itraconazole was complete or major for 15 and minor for 17. Overall, endemicity of sporotrichosis in Madagascar was high, concentrated in the highlands.