Journal of medical case reports · 2025
Metastatic colon involvement from primary adrenal gland angiosarcoma: a case report.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
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Ben Rejeb Sarra, Sakly Safia, Bahloul Rym, Jomni Taieb, Dridi Kalthoum
Аннотация
INTRODUCTION: Angiosarcoma is a rare and aggressive malignancy accounting for 1-2% of soft tissue sarcomas. Primary adrenal angiosarcomas are exceptionally rare, with fewer than 60 cases reported.To our knowledge, this is the first documented case of an adrenal angiosarcoma presenting as a colonic metastasis.
CASE REPORT: A 68-year-old Caucasian North African woman with a history of adrenalectomy for a right adrenal tumor presented with gastrointestinal bleeding, and endoscopy revealed a hemorrhagic ulcerative lesion in the sigmoid colon. Histopathological examination revealed a malignant vascular tumor. Immunohistochemistry showed positivity for CD31, erythroblastosis virus E26 transforming sequence related gene, and pan-cytokeratin, consistent with angiosarcoma. In light of her history, a review of the adrenalectomy specimen confirmed the diagnosis of primary adrenal angiosarcoma.
CONCLUSION: This case underscores the necessity of thorough pathological evaluation, use of vascular markers, and interdisciplinary collaboration to improve diagnosis and management.
CASE REPORT: A 68-year-old Caucasian North African woman with a history of adrenalectomy for a right adrenal tumor presented with gastrointestinal bleeding, and endoscopy revealed a hemorrhagic ulcerative lesion in the sigmoid colon. Histopathological examination revealed a malignant vascular tumor. Immunohistochemistry showed positivity for CD31, erythroblastosis virus E26 transforming sequence related gene, and pan-cytokeratin, consistent with angiosarcoma. In light of her history, a review of the adrenalectomy specimen confirmed the diagnosis of primary adrenal angiosarcoma.
CONCLUSION: This case underscores the necessity of thorough pathological evaluation, use of vascular markers, and interdisciplinary collaboration to improve diagnosis and management.