Dermatological manifestations of Down's syndrome.

BACKGROUND

Down's syndrome (DS) is an extensively researched congenital condition characterized by mental retardation and distinct physical features. The cutaneous manifestations of DS are numerous, yet they seldom receive appropriate attention.

OBJECTIVE

To review the dermatological conditions associated with DS.

METHODS

A review of the medical literature.

RESULTS

DS is associated with an increased incidence of numerous dermatological conditions, some of which may be related to an immunological deficiency.

CONCLUSION

Along with the importance of understanding the physical and psychosocial aspects of DS, an appreciation of the dermatological manifestations of this condition is integral to comprehensive medical care.