Journal of pediatric urology · 2025
Use and institutional variation in surgical antibiotic prophylaxis for pediatric clean (class I) penile and groin procedures.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Frainey Brendan T, Zaniletti Isabella, Peard Leslie M, Katz Sophie E, Corona Lauren E
Аннотация
BACKGROUND: The majority of ambulatory pediatric penile, inguinal and scrotal cases are considered clean (class I) surgical wounds and guidelines do not recommend surgical antibiotic prophylaxis (SAP) use. Despite these recommendations, few data exist that have assessed utilization and outcomes of interest associated with SAP use for ambulatory pediatric urology procedures.
OBJECTIVE: To better understand national and individual hospital utilization of SAP for common, ambulatory pediatric urologic procedures at lowest risk for surgical site infection (SSI) and for which the benefits of SAP are limited.
STUDY DESIGN: We queried the Pediatric Health Information System (PHIS) database for males (29 days-18 years) undergoing outpatient penile and/or "groin" (inguinal/scrotal) procedures from 2016 to 2023. SAP use was abstracted. Demographic and clinical characteristics were compared between procedures with no SAP use vs. any SAP use and a multivariable logistic regression model with generalized estimating equation to account for clustered data on hospitals was performed to identify factors associated with increased odds of use. Secondary outcomes of interest included post-operative ED visits, surgical site infections, allergic reactions, and Clostridium difficile infections. National trends in SAP use were compared by year and between hospitals that consistently reported data over the study period.
RESULTS: A total of 108,419 procedures (46 % penile, 42 % groin, 12 % combination) were included. Median age at surgery was 2 (IQR 0,7) years. Overall, 14 % of procedures had SAP use. Groin procedures had higher rates of antibiotic use compared to penile procedures (19 % vs 8 %, p < 0.001). On adjusted analysis, groin procedures (aOR 2.12), combined groin + penile procedures (aOR 2.43), older age (aOR 2.54), and urologist as proceduralist (aOR 1.52) were independently associated with greater odds of antibiotic use. Rates of secondary outcomes were similar between groups. There was significant variability in SAP between centers (range 0 %-32 % groin; 0 %-16.7 % penile, p < 0.001) over the study period (Figure 1B).
DISCUSSION: SAP use for uncomplicated pediatric penile and groin procedures was 14 % overall, with variability in use between hospitals. Groin procedures, older patients, and a urologic proceduralist were associated with increased odds of antibiotic use.
CONCLUSION: Despite improvements over time, SAP use persists for uncomplicated, clean pediatric urologic procedures, with significant variability across centers. This highlights an opportunity for standardization of practice within pediatric urology to optimize the balance between SSI prevention and promotion of antimicrobial stewardship.
OBJECTIVE: To better understand national and individual hospital utilization of SAP for common, ambulatory pediatric urologic procedures at lowest risk for surgical site infection (SSI) and for which the benefits of SAP are limited.
STUDY DESIGN: We queried the Pediatric Health Information System (PHIS) database for males (29 days-18 years) undergoing outpatient penile and/or "groin" (inguinal/scrotal) procedures from 2016 to 2023. SAP use was abstracted. Demographic and clinical characteristics were compared between procedures with no SAP use vs. any SAP use and a multivariable logistic regression model with generalized estimating equation to account for clustered data on hospitals was performed to identify factors associated with increased odds of use. Secondary outcomes of interest included post-operative ED visits, surgical site infections, allergic reactions, and Clostridium difficile infections. National trends in SAP use were compared by year and between hospitals that consistently reported data over the study period.
RESULTS: A total of 108,419 procedures (46 % penile, 42 % groin, 12 % combination) were included. Median age at surgery was 2 (IQR 0,7) years. Overall, 14 % of procedures had SAP use. Groin procedures had higher rates of antibiotic use compared to penile procedures (19 % vs 8 %, p < 0.001). On adjusted analysis, groin procedures (aOR 2.12), combined groin + penile procedures (aOR 2.43), older age (aOR 2.54), and urologist as proceduralist (aOR 1.52) were independently associated with greater odds of antibiotic use. Rates of secondary outcomes were similar between groups. There was significant variability in SAP between centers (range 0 %-32 % groin; 0 %-16.7 % penile, p < 0.001) over the study period (Figure 1B).
DISCUSSION: SAP use for uncomplicated pediatric penile and groin procedures was 14 % overall, with variability in use between hospitals. Groin procedures, older patients, and a urologic proceduralist were associated with increased odds of antibiotic use.
CONCLUSION: Despite improvements over time, SAP use persists for uncomplicated, clean pediatric urologic procedures, with significant variability across centers. This highlights an opportunity for standardization of practice within pediatric urology to optimize the balance between SSI prevention and promotion of antimicrobial stewardship.