The Journal of the Association of Physicians of India · 2001
2-CdA in the treatment of hairy cell leukaemia.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Abhyankar D, Bajpai S, Saikia T, Gopal R, Nair C N, Advani S H
Аннотация
INTRODUCTION: Hairy cell leukaemia (HCL) is a rare lymphoproliferative disorder. Treatment options available are splenectomy, interferon, DCF and 2-CdA. 2-CdA is considered to have curative potential as proved by the other studies.
METHODS: We gave 2-CdA in a dose of 0.09/kg/day as a continuous infusion in sixteen patients of hairy cell leukaemia.
RESULTS: Three patients developed neutropenia post transfusion. At the end of three months all patients were in remission. Two patients relapsed at the median follow-up of 15 months.
CONCLUSION: 2-CdA in HCL can achieve complete remission, prolonged survival and care as well.
METHODS: We gave 2-CdA in a dose of 0.09/kg/day as a continuous infusion in sixteen patients of hairy cell leukaemia.
RESULTS: Three patients developed neutropenia post transfusion. At the end of three months all patients were in remission. Two patients relapsed at the median follow-up of 15 months.
CONCLUSION: 2-CdA in HCL can achieve complete remission, prolonged survival and care as well.