Ticks and tick-borne diseases · 2020
Isolation and characterization of Wad Medani virus obtained in the tuva Republic of Russia.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Dedkov Vladimir G, Dolgova Anna S, Safonova Marina V, Samoilov Andrei E, Belova Oxana A, Kholodilov Ivan S, Matsvay Alina D, Speranskaya Anna S, Khafizov Kamil, Karganova Galina G
Аннотация
Wad Medani virus (WMV) belongs to the genus Orbivirus and is a poorly studied arbovirus with unclear medical significance. Presently, a limited number of WMV strains are characterized and available in NCBI GenBank, some isolated many years ago. A new WMV strain was isolated in 2012 from Dermacentor nuttalli ticks collected from sheep in the Tuva Republic, Russia, and sequenced using high-throughput methods. Complete coding sequences were obtained revealing signs of multiple intersegment reassortments. These point to a high variability potential in WMV that may lead to the formation of strains with novel properties. These new data on WMV can promote better understanding of: ecological features of its circulation; relationships within the genus Orbivirus; and the medical significance of the virus.