Predictive Factors for Successful Testicular Biopsy in Azoospermia [cite: 100].

Testicular biopsy represents a crucial procedure in the management of non-obstructive azoospermia, though its success remains variable. [cite: 106] Identifying predictive factors for successful sperm retrieval is essential for patient selection. [cite: 107] Aim: To determine the clinical, hormonal and technical factors predictive of successful testicular biopsy in azoospermic patients [cite: 108] Methods: A retrospective analytical study was conducted over 5 years (2017-2021), including 28 patients. [cite: 109] Comparative analysis was performed between groups with successful (spermatozoa present) and failed biopsy. [cite: 110] Results: Significant predictive factors for successful biopsy included: testicular volume preservation (p=0.042), low FSH levels (p=0.002), low estradiol levels (p=0.018), excretory azoospermia type (p=0.023), and unilateral surgical approach (p=0.005). [cite: 111] Clinical varicocele and hydrocele showed no significant correlation. [cite: 112] Conclusion: Our study identifies a predictive profile for testicular biopsy success, enabling better patient selection and surgical strategy optimization in assisted reproductive technology. [cite: 113].