Head & neck · 2019
Impact of varying anatomic sites on advanced stage and survival of oral cancer: 9-year prospective cohort of 27 717 cases.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Su William Wang-Yu, Su Chiu-Wen, Chang Dun-Cheng, Chuang Shu-Lin, Chen Sam Li-Sheng, Hsu Chen-Yang, Yen Amy Ming-Fang, Chiu Sherry Yueh-Hsia, Fann Jean Ching-Yuan, Lee Yi-Huah, Jeng Ya-Chung, Lee Yi-Chia, Chiu Han-Mo, Chen Tony Hsiu-Hsi, Wang Cheng-Ping, Chen Mu-Kuan
Аннотация
BACKGROUND: To elucidate the impact of varying anatomic sites on advanced stage of and death from oral cancer.
METHODS: A total of 27 717 oral cancers mainly from a population-based visual inspection program in Taiwan from 2004 to 2009 was followed until the end of 2012.
RESULTS: Using lip cancer as reference, the odds ratios (95% confidence interval [CI]) of advanced stage of cancer were 2.20 (1.92-2.51) for tongue, 2.60 (2.28-2.97) for buccal, 2.68 (2.20-3.28) for floor of mouth, 2.96 (2.52-3.47) for hard palate, 6.04 (5.17-7.05) for gingiva, and 10.83 (9.20-12.74) for oropharynx. The estimated hazard ratios (95% CI) for oral cancer death increased from 1.48 (1.31-1.67) in buccal, 1.61 (1.43-1.82) in tongue, 1.68 (1.41-1.99) in floor of mouth, 1.79 (1.57-2.05) in gingiva, 1.97 (1.71-2.26) in hard palate, and 2.15 (1.89-2.45) in oropharynx.
CONCLUSION: Different anatomic sites had variations in advanced stage of and death from oral cancer and need vigilant surveillance.
METHODS: A total of 27 717 oral cancers mainly from a population-based visual inspection program in Taiwan from 2004 to 2009 was followed until the end of 2012.
RESULTS: Using lip cancer as reference, the odds ratios (95% confidence interval [CI]) of advanced stage of cancer were 2.20 (1.92-2.51) for tongue, 2.60 (2.28-2.97) for buccal, 2.68 (2.20-3.28) for floor of mouth, 2.96 (2.52-3.47) for hard palate, 6.04 (5.17-7.05) for gingiva, and 10.83 (9.20-12.74) for oropharynx. The estimated hazard ratios (95% CI) for oral cancer death increased from 1.48 (1.31-1.67) in buccal, 1.61 (1.43-1.82) in tongue, 1.68 (1.41-1.99) in floor of mouth, 1.79 (1.57-2.05) in gingiva, 1.97 (1.71-2.26) in hard palate, and 2.15 (1.89-2.45) in oropharynx.
CONCLUSION: Different anatomic sites had variations in advanced stage of and death from oral cancer and need vigilant surveillance.
Предметные рубрики MeSH
AdultAgedAlcoholismCause of DeathCheekCohort StudiesConfidence IntervalsDisease-Free SurvivalEarly Detection of CancerFemaleGingivaHumansMaleMiddle AgedMouth FloorMouth NeoplasmsNeoplasm InvasivenessNeoplasm StagingOdds RatioOropharynxPalate, HardProspective StudiesRisk AssessmentSmokingSurvival AnalysisTaiwanYoung Adult