[Dynamics of hepatobiliary system involvement in occupational COLD formation].

Study of 462 patients with occupational pulmonary diseases revealed that hepatobiliary diseases are among concomitants of occupational COLD. Inflammatory changes in gallbladder and bile ducts with bile dyskinesia are first manifestations of such diseases developing early at chronic nonobstructive bronchitis stage. Shortly, hepatosteatosis adds to these disorders. Final stage of the pathologic process in some patients is bile stones or liver cirrhosis.