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Войти в исследования Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2025
Auditory Characteristics in Children With Enlarged Vestibular Aqueduct.
СтатьяНазвание и аннотация: Перевод в очереди
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Patel Punam, Parkes William, Pritchett Cedric, Stewart Matthew, Choudhari Arabinda, Nikam Rahul, Hossain Jobayer, O'Reilly Robert, Morlet Thierry
Аннотация
OBJECTIVE: Enlarged vestibular aqueduct (EVA) is the most common radiographic finding in children diagnosed with congenital sensorineural hearing loss (SNHL). Many institutions use the Cincinnati criteria for diagnosis: width ≥2.0 mm at the operculum and/or ≥1.0 mm at the midpoint. Our goals are to expand our understanding of EVA by examining the audiometric and auditory brainstem response (ABR) characteristics of a large population of children with EVA and hearing loss.
STUDY DESIGN: Retrospective chart review.
SETTING: Tertiary-care children's hospital.
PATIENTS: All children diagnosed with EVA from 2006 to 2016.
INTERVENTIONS: Diagnostic.
MAIN OUTCOME MEASURES: Vestibular aqueduct measurements were taken at the operculum.
RESULTS: One hundred six patients were included (63 females; 60 bilateral EVA). The age of hearing loss diagnosis was significantly younger in patients with bilateral EVA compared with unilateral (0.0 [0-3] yr versus 5.0 [0.9-7.0] yr, p = 0.001). The most common pattern seen on ABR was SNHL-like (57%), followed by large wave I pattern (28.6%), followed by auditory neuropathy spectrum disorder (14.3%). Patients with bilateral EVA were more likely to have progressive hearing loss compared with patients with unilateral EVA ( p = 0.001). There was no correlation between EVA size and hearing stability or between EVA size and pure-tone average at the time of diagnosis.
CONCLUSION: There is a wide range of clinical manifestations of EVA, though we found no significant correlation between size and progressiveness or severity. The clinical significance of a large wave I tracing on ABR is not fully understood and warrants further research.
STUDY DESIGN: Retrospective chart review.
SETTING: Tertiary-care children's hospital.
PATIENTS: All children diagnosed with EVA from 2006 to 2016.
INTERVENTIONS: Diagnostic.
MAIN OUTCOME MEASURES: Vestibular aqueduct measurements were taken at the operculum.
RESULTS: One hundred six patients were included (63 females; 60 bilateral EVA). The age of hearing loss diagnosis was significantly younger in patients with bilateral EVA compared with unilateral (0.0 [0-3] yr versus 5.0 [0.9-7.0] yr, p = 0.001). The most common pattern seen on ABR was SNHL-like (57%), followed by large wave I pattern (28.6%), followed by auditory neuropathy spectrum disorder (14.3%). Patients with bilateral EVA were more likely to have progressive hearing loss compared with patients with unilateral EVA ( p = 0.001). There was no correlation between EVA size and hearing stability or between EVA size and pure-tone average at the time of diagnosis.
CONCLUSION: There is a wide range of clinical manifestations of EVA, though we found no significant correlation between size and progressiveness or severity. The clinical significance of a large wave I tracing on ABR is not fully understood and warrants further research.