[Serum levels of glycosaminoglycans, hydroxyproline, and fibronectin in patients with spinal osteochondrosis].

The content of the major components of the extracellular matrix was studied in 60 patients with spinal osteochondrosis over time during complex rehabilitative therapy including radon-containing mineral baths (before, 7-9 and 14-15 days after treatment). The complex rehabilitative treatment using radon baths in patients with spinal osteochondrosis was shown to result in a reduction in the serum level of glycosaminoglycans (GAG) and total oxyproline by the end of a course of therapy, which suggests the lower rate of destructive processes in the extracellular matrix. The determination of GAG concentrations and oxyproline forms in patients with asteochondrosis may be used to evaluate the efficiency of the treatment performed.