Clinico-immunological profile of juvenile rheumatoid arthritis at Chandigarh.

OBJECTIVE

To study the clinical and immunological profile of children with juvenile rheumatoid arthritis (JRA).

DESIGN

Retrospective hospital based study.

SETTING

Tertiary level center of North India.

SUBJECTS: 74 patients attending the Pediatric Rheumatology and Immunology Clinic over last 5 years.

RESULTS

The patients were aged between 9 months to 12 years with male female ratio of 1.8:1. Eleven (14.9%) patients had systemic onset JRA, 28 (37.8%) had polyarticular onset type and 35(47.3%) had pauciarticular onset type JRA. Uveitis was present only in one patient and rheumatoid nodules were present in 4(5.4%) patients. Rheumatoid factor was positive in 2(2.7%) and antinuclear antibody was present in one patient only. HLA-B27 was positive in 4 children. Two patients developed amyloidosis.

CONCLUSION

The clinico-immunological profile of JRA at Chandigarh appears to be some what different from that reported from other centers in India.