[What is new in pediatric rheumatological diseases?].

Juvenile idiopathic arthritis (JIA) and systemic lupus erythematosus (SLE) are complex pediatric rheumatologic diseases with a significant genetic component. These conditions include various subtypes, each of which presents unique diagnostic and therapeutic challenges. Recent advances in biotherapy and genetics have revolutionized the management of these diseases, allowing for more targeted and effective treatments. This article explores the different aspects of JIA and SLE, as well as pediatric systemic vasculitis and certain immune deficiencies associated with dysimmunity, and highlights recent progress in the understanding and treatment of these diseases.