The role of skin and subcutaneous tissues in Dupuytren's contracture: an electron microscopic observation.

OBJECTIVE

To determine the relationship between the overlying tissues and recurrence of Dupuytren's contracture.

METHODS

Forty-three patients (68 hands) who accepted surgical treatment were divided into two groups according to treatment methods: partial fasciectomy or dermofasciectomy and full-thickness skin graft. Diseased palmar fascia, subcutaneous tissues and skin obtained during surgery were then assessed by electron microscopy.

RESULTS

All patients were followed up. None of the hands which accepted dermofasciectomy and full-thickness skin grafting recurred, while 46.4% of the hands which accepted partial fasciectomy recurred. Under electron microscopic observation, myofibroblasts were found in the skin and subcutaneous tissues.

CONCLUSION

The overlying tissues play an important role in Dupuytren's contracture, which may be a reason for recurrence of this condition after surgical treatment.