The Journal of rheumatology · 2019
Risk of Diabetes Mellitus in Patients with Juvenile Idiopathic Arthritis.
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Lee Hemin, Jin Yinzhu, Liu Jun, Cohen Ezra M, Chen Sarah K, Kim Seoyoung C
Аннотация
OBJECTIVE: To examine the risk of type 1 diabetes (T1D) associated with juvenile idiopathic arthritis (JIA).
METHODS: Using the IBM MarketScan database, we compared JIA patients with asthma patients and healthy individuals for the risk of incident T1D.
RESULTS: We included patients with 15,210 JIA, 76,050 patients with asthma, and 76,050 healthy individuals matched 1:5 on age, sex, and index date. After adjustment for confounders, the multivariable HR of T1D associated with JIA was 1.48 (95% CI 0.86-2.56) versus asthma and 1.81 (95% CI 1.03-3.17) versus healthy individuals.
CONCLUSION: JIA appears to be associated with an increased risk of T1D compared to patients with asthma and healthy children.
METHODS: Using the IBM MarketScan database, we compared JIA patients with asthma patients and healthy individuals for the risk of incident T1D.
RESULTS: We included patients with 15,210 JIA, 76,050 patients with asthma, and 76,050 healthy individuals matched 1:5 on age, sex, and index date. After adjustment for confounders, the multivariable HR of T1D associated with JIA was 1.48 (95% CI 0.86-2.56) versus asthma and 1.81 (95% CI 1.03-3.17) versus healthy individuals.
CONCLUSION: JIA appears to be associated with an increased risk of T1D compared to patients with asthma and healthy children.