Every member of the kingdom Animalia is a potential vector of human pathogens.

Zoonotic diseases are a subset of infectious diseases, which account for enormous morbidity and mortality. Pathologies like malaria, rabies, Lyme disease, leptospirosis, avian flu etc. are microbe- and parasite-caused ailments, where the etiological agents are introduced into or on the human body via ticks, mosquitoes, birds, rodents, bats, and deer, among other members of kingdom Animalia. While some of the zoonotic diseases are well-investigated and caution taken against, a lot many are yet to be recognized. This ignorance costs health, and lives, especially in developing countries. To promote awareness regarding the risks of immunogenicity and pathogen dissemination by hitherto unknown non-plant organisms, the members of kingdom Animalia, this letter has been compiled. The vector exploitation mechanisms of the pathogens, and in silico evidences of conserved protein domains across the potential pathogen reservoirs have been mentioned to underline the importance of this topic.