Clinical nutrition ESPEN · 2026
Evidence on protein intake on lean body mass and function in community-dwelling adults aged 50 years and over living with multiple long-term conditions: Systematic review.
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Ahmed Saima, MacKenzie Aylish, Eost-Telling Charlotte, French Chloe, Christie Rachel A, Karami Ahmadreza, Todd Chris, Vardy Emma, Burden Sorrel, Money Annemarie
Аннотация
BACKGROUND: Older adults are at higher risk of developing multiple long-term conditions (MLTCs) in later life and diet can play an important role in the development/management of these conditions. Healthy eating policies can improve nutrition in people with MLTCs. However, specialised diets may lead to restrictive eating patterns and lower protein intake.
OBJECTIVES: The current evidence around protein intake and MLTCs is limited. This review aims to examine the available evidence on protein intake on body composition and function in older adults with MLTCs.
METHODS: A systematic review was conducted to assess the impact of protein intake on muscle mass, body mass index, muscle strength and muscle quality in community-dwelling older adults aged 50+ years living with MLTCs (PROSPERO:CRD42024528580).
RESULTS: Seven studies were included in this review (median age 71, range 64-85+ years). Sample sizes ranged from 28 to 932 participants, comprising of community-dwelling adults with chronic kidney disease, sarcopenia, cancer, and obesity. Only two studies had protein intake as their intervention of interest. None of the studies analysed the impact of protein intake on body composition and function in relation to MLTCs.
CONCLUSION: Evidence examining the impact of protein intake in adults with MLTCs was limited. Protein intake was reported as a patient characteristic for many studies, with inadequate follow-up assessments. Comparability of findings was challenging due to the range of outcome measures used. Future studies need to focus on protein intake as the primary intervention and incorporate long-term post-intervention follow-up periods with adequately powered study samples.
OBJECTIVES: The current evidence around protein intake and MLTCs is limited. This review aims to examine the available evidence on protein intake on body composition and function in older adults with MLTCs.
METHODS: A systematic review was conducted to assess the impact of protein intake on muscle mass, body mass index, muscle strength and muscle quality in community-dwelling older adults aged 50+ years living with MLTCs (PROSPERO:CRD42024528580).
RESULTS: Seven studies were included in this review (median age 71, range 64-85+ years). Sample sizes ranged from 28 to 932 participants, comprising of community-dwelling adults with chronic kidney disease, sarcopenia, cancer, and obesity. Only two studies had protein intake as their intervention of interest. None of the studies analysed the impact of protein intake on body composition and function in relation to MLTCs.
CONCLUSION: Evidence examining the impact of protein intake in adults with MLTCs was limited. Protein intake was reported as a patient characteristic for many studies, with inadequate follow-up assessments. Comparability of findings was challenging due to the range of outcome measures used. Future studies need to focus on protein intake as the primary intervention and incorporate long-term post-intervention follow-up periods with adequately powered study samples.