[Condylar adaptation triggered by SGTB orthopedic therapy-Biological mechanism and clinical significance].

Endochondral ossification constitutes biological and phenotypic foundation for condylar growth. Adaptive response of condylar cartilage to mandibular advancement, on the other hand, facilities condylar remodeling generated by SGTB （sagittal-guided twin block）orthopedic therapy. This enables SGTB to correct increased overjet and overbite by eliminating jaws discrepancy. It is also an encouraging advance that SGTB therapy is used to intervene temporo-mandibular joint disorders (TMD) by regenerating the degraded condylar cartilage.