The Lancet. Global health · 2025
Causes of death in rural southeast Asia by electronic verbal autopsy: a population-based observational study.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Htun Nan Shwe Nwe, Phommasone Koukeo, Perrone Carlo, Phyo Aung Pyae, Sen Aninda, Vanna Moul, Tripura Rupam, Kabir Nawrin, Islam Md Akramul, Wirachonphaophong Jindaporn, Panyadee Patcharaporn, Chandna Arjun, Boonyoung Supachai, Lek Dysoley, Pongvongsa Tiengkham, Mayxay Mayfong, Kamadod Rajeev, Day Nicholas P J, Morris Shaun K, Ashley Elizabeth A, Jha Prabhat, Lee Sue J, Lubell Yoel, Peto Thomas J
Аннотация
BACKGROUND: In low-income and middle-income countries in southeast Asia, most deaths occur outside of the health-care system without a medically certified cause of death. We did a verbal autopsy study to determine the underlying causes of death in rural areas of the region and to estimate premature mortality using years of life lost (YLLs).
METHODS: In this population-based observational study, we conducted electronic verbal autopsy surveys for reported deaths in 510 villages in Bangladesh, Cambodia, Laos, Myanmar, and Thailand from 2021 to 2024. With the WHO 2016 verbal autopsy questionnaire, trained fieldworkers conducted interviews, and local physicians independently assigned causes of death by ICD-10 codes. Causes of death were ranked based on cause-specific mortality fractions (CSMFs), and YLLs calculated using corresponding national life expectancy.
FINDINGS: Over 90% of reported deaths had a verbal autopsy administered. Among 3413 deaths, 2052 (60%) were male and 1361 (40%) were female, and 3245 (95%) were older than 12 years. Across sites, 64-86% of deaths occurred at home. Non-communicable diseases were the leading causes of death, ranging from 54% in Laos to 70% in Cambodia, with cardiovascular, cerebrovascular, cancer, and digestive conditions being the most common. Maternal, nutritional, and communicable diseases, mainly respiratory infections, diarrhoea, and tuberculosis, accounted for 11-26% of deaths across the sites. Accidents and injuries comprised 7-13% and ranked among the top five causes. Major gaps in death documentation persist across all countries, whereas disease-specific causes of death varied between sites. Non-communicable diseases accounted for the majority of YLLs, representing between 56% and 65% across the five countries.
INTERPRETATION: This multicountry study highlighted the significant burden of non-communicable diseases in rural southeast Asia, alongside persistent communicable diseases, emphasising the need for better mortality data and health-care access to reduce this dual burden.
FUNDING: Wellcome Trust.
TRANSLATIONS: For the Myanmar, Karen, Bangla, Thai, Lao and Khmer translations of the abstract see Supplementary Materials section.
METHODS: In this population-based observational study, we conducted electronic verbal autopsy surveys for reported deaths in 510 villages in Bangladesh, Cambodia, Laos, Myanmar, and Thailand from 2021 to 2024. With the WHO 2016 verbal autopsy questionnaire, trained fieldworkers conducted interviews, and local physicians independently assigned causes of death by ICD-10 codes. Causes of death were ranked based on cause-specific mortality fractions (CSMFs), and YLLs calculated using corresponding national life expectancy.
FINDINGS: Over 90% of reported deaths had a verbal autopsy administered. Among 3413 deaths, 2052 (60%) were male and 1361 (40%) were female, and 3245 (95%) were older than 12 years. Across sites, 64-86% of deaths occurred at home. Non-communicable diseases were the leading causes of death, ranging from 54% in Laos to 70% in Cambodia, with cardiovascular, cerebrovascular, cancer, and digestive conditions being the most common. Maternal, nutritional, and communicable diseases, mainly respiratory infections, diarrhoea, and tuberculosis, accounted for 11-26% of deaths across the sites. Accidents and injuries comprised 7-13% and ranked among the top five causes. Major gaps in death documentation persist across all countries, whereas disease-specific causes of death varied between sites. Non-communicable diseases accounted for the majority of YLLs, representing between 56% and 65% across the five countries.
INTERPRETATION: This multicountry study highlighted the significant burden of non-communicable diseases in rural southeast Asia, alongside persistent communicable diseases, emphasising the need for better mortality data and health-care access to reduce this dual burden.
FUNDING: Wellcome Trust.
TRANSLATIONS: For the Myanmar, Karen, Bangla, Thai, Lao and Khmer translations of the abstract see Supplementary Materials section.