Ocular immunology and inflammation · 2015
Foveal Serous Retinal Detachment in Juvenile Idiopathic Arthritis-associated Uveitis.
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Liang Feng, Terrada Celine, Ducos de Lahitte Ghislaine, Quartier Pierre, Lehoang Phuc, Thorne Jennifer E, Bodaghi Bahram
Аннотация
PURPOSE: In juvenile idiopathic arthritis (JIA)-associated uveitis complicated by foveal serous retinal detachment (FSRD), we documented the relationship between best corrected visual acuity (BCVA), level of anterior chamber flare and OCT features.
METHODS: Nine children (15 eyes) with FSRD were identified among 38 children with JIA-associated maculopathy. Outcome measures included BCVA, ocular inflammatory activity quantified by laser flare photometry and the macular profile analyzed by OCT.
RESULTS: The diagnosis of FSRD led to intensification of the treatment using subtenon's injection of triamcinolone or systemic immunomodulatory therapy. The improvement of BCVA at presentation (0.46 logMAR) was significant at 36 months follow-up (0.15 logMAR). The resolution of FSRD along with visual improvement (p = 0.0032) correlated with improvement in anterior chamber flare (p = 0.01).
CONCLUSION: FSRD is a complication of chronic JIA-associated uveitis that responds well to intensification of immunomodulation. Visual improvement is correlated with FSRD resolution and with flare photometry values.
METHODS: Nine children (15 eyes) with FSRD were identified among 38 children with JIA-associated maculopathy. Outcome measures included BCVA, ocular inflammatory activity quantified by laser flare photometry and the macular profile analyzed by OCT.
RESULTS: The diagnosis of FSRD led to intensification of the treatment using subtenon's injection of triamcinolone or systemic immunomodulatory therapy. The improvement of BCVA at presentation (0.46 logMAR) was significant at 36 months follow-up (0.15 logMAR). The resolution of FSRD along with visual improvement (p = 0.0032) correlated with improvement in anterior chamber flare (p = 0.01).
CONCLUSION: FSRD is a complication of chronic JIA-associated uveitis that responds well to intensification of immunomodulation. Visual improvement is correlated with FSRD resolution and with flare photometry values.
Предметные рубрики MeSH
AdolescentAdultAnterior ChamberAnti-Inflammatory Agents, Non-SteroidalArthritis, JuvenileChildChild, PreschoolFemaleFollow-Up StudiesFovea CentralisGlucocorticoidsHumansImmunosuppressive AgentsMalePhotometryRetinal DetachmentSubretinal FluidTomography, Optical CoherenceUveitis, AnteriorVisual Acuity