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DOI 10.1097/mpg.0000000000002205

Медицинская библиотека · Journal of pediatric gastroenterology and nutrition · 2019

Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children: A Joint Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

Davidovics Zev H, Michail Sonia, Nicholson Maribeth R, Kociolek Larry K, Pai Nikhil, Hansen Richard, Schwerd Tobias, Maspons Aldo, Shamir Raanan, Szajewska Hania, Thapar Nikhil, de Meij Tim, Mosca Alexis, Vandenplas Yvan, Kahn Stacy A, Kellermayer Richard, FMT Special Interest Group of the North American Society of Pediatric Gastroenterology Hepatology, Nutrition, the European Society for Pediatric Gastroenterology Hepatology, Nutrition

СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАConsensus StatementПеревод в очереди

Аннотация

Fecal microbiota transplantation (FMT) is becoming part of the treatment algorithms against recurrent Clostridium difficile infection (rCDI) both in adult and pediatric gastroenterology practice. With our increasing recognition of the critical role the microbiome plays in human health and disease, FMT is also being considered as a potential therapy for other disorders, including inflammatory bowel disease (Crohn disease, ulcerative colitis), graft versus host disease, neuropsychiatric diseases, and metabolic syndrome. Controlled trials with FMT for rCDI have not been performed in children, and numerous clinical and regulatory considerations have to be considered when using this untraditional therapy. This report is intended to provide guidance for FMT in the treatment of rCDI in pediatric patients.

Для цитирования: Davidovics Zev H, Michail Sonia, Nicholson Maribeth R, Kociolek Larry K, Pai Nikhil, Hansen Richard, Schwerd Tobias, Maspons Aldo, Shamir Raanan, Szajewska Hania, Thapar Nikhil, de Meij Tim, Mosca Alexis, Vandenplas Yvan, Kahn Stacy A, Kellermayer Richard, FMT Special Interest Group of the North American Society of Pediatric Gastroenterology Hepatology, Nutrition, the European Society for Pediatric Gastroenterology Hepatology, Nutrition. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children: A Joint Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.. Journal of pediatric gastroenterology and nutrition. 2019. DOI: 10.1097/mpg.0000000000002205.

Предметные рубрики MeSH

ChildClostridioides difficileEnterocolitis, PseudomembranousEuropeFecal Microbiota TransplantationGastroenterologyHumansNorth AmericaPediatricsSocieties, Medical
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